| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Amsacrine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Amsacrine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.203367 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.109564 |
| INTS6 | integrator complex subunit 6 | 0.0995418 |
| LYZ | lysozyme | 0.0875503 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0802442 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0797418 |
| PKM | pyruvate kinase, muscle | 0.0683033 |
| PLSCR2 | phospholipid scramblase 2 | 0.061939 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0569655 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0551381 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0547961 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0541011 |
| FAT1 | FAT atypical cadherin 1 | 0.0529676 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0527674 |
| ITGA6 | integrin, alpha 6 | 0.0522242 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0497072 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.048378 |
| B2M | beta-2-microglobulin | 0.0459492 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0455014 |
| SEPTIN9 | septin 9 | 0.0450327 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0449374 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0445916 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0441739 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0430073 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0423803 |
| PRKCA | protein kinase C, alpha | 0.0419192 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0417746 |
| TMC5 | transmembrane channel-like 5 | 0.0404565 |
| RUNX1 | runt-related transcription factor 1 | 0.0400654 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0391652 |
| VEGFA | vascular endothelial growth factor A | 0.0376533 |
| EPHB2 | EPH receptor B2 | 0.0373493 |
| ANXA2 | annexin A2 | 0.037021 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0363962 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0354022 |
| RNF43 | ring finger protein 43 | 0.0348573 |
| TRERF1 | transcriptional regulating factor 1 | 0.0339122 |
| ABHD2 | abhydrolase domain containing 2 | 0.0336864 |
| EZR | ezrin | 0.033228 |
| ANXA4 | annexin A4 | 0.0327435 |
| MSI2 | musashi RNA-binding protein 2 | 0.0326789 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0325462 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0322389 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0321676 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0318197 |
| ENO1 | enolase 1, (alpha) | 0.0315036 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.03106 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0310026 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0297881 |
| TXNIP | thioredoxin interacting protein | 0.0297144 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0291498 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0290845 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0290813 |
| MCL1 | myeloid cell leukemia 1 | 0.0289034 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.028697 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0279158 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.027039 |
| IL20RA | interleukin 20 receptor, alpha | 0.026733 |
| HLA-A | major histocompatibility complex, class I, A | 0.0265719 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0265668 |
| PDZD8 | PDZ domain containing 8 | 0.0263994 |
| TTC39B | tetratricopeptide repeat domain 39B | 0.0263075 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0262625 |
| EGR1 | early growth response 1 | 0.0253543 |
| TMEM45B | transmembrane protein 45B | 0.0250724 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0241913 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0241615 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0239777 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0234046 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0229169 |
| ZNRF3 | zinc and ring finger 3 | 0.0229056 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0227053 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0225125 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0224478 |
| KRT18 | keratin 18, type I | 0.0221621 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0220522 |
| SFTPA2 | surfactant protein A2 | 0.0219484 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0218 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0217781 |
| BRD2 | bromodomain containing 2 | 0.0217604 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0217462 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.021732 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0216677 |
| CMIP | c-Maf inducing protein | 0.0214768 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.0214405 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0213303 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0212495 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0212265 |
| APP | amyloid beta (A4) precursor protein | 0.0209542 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0208414 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0208293 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0207887 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0207359 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.020687 |
| DST | dystonin | 0.0205711 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0205568 |
| NRDC | nardilysin convertase | 0.0205377 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0202338 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0199673 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0199023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.122242 |
| MACC1 | metastasis associated in colon cancer 1 | -0.120589 |
| MYO1E | myosin IE | -0.0874183 |
| VCL | vinculin | -0.0828142 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.079578 |
| SP100 | SP100 nuclear antigen | -0.0772485 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0739044 |
| SPATA13 | spermatogenesis associated 13 | -0.0652883 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0588796 |
| NCKAP5 | NCK-associated protein 5 | -0.0544533 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0521067 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.051802 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0507362 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0503618 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0499927 |
| ERBIN | erbb2 interacting protein | -0.0495439 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.049322 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0488951 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0481118 |
| PLSCR1 | phospholipid scramblase 1 | -0.047338 |
| TJP1 | tight junction protein 1 | -0.0472906 |
| KLF6 | Kruppel-like factor 6 | -0.0459165 |
| RIGI | RNA sensor RIG-I | -0.0443489 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0434213 |
| ETV6 | ets variant 6 | -0.0429093 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0424486 |
| DIAPH3 | diaphanous-related formin 3 | -0.0423372 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0411496 |
| ZNF292 | zinc finger protein 292 | -0.0409316 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0407554 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0406236 |
| MUC20 | mucin 20, cell surface associated | -0.0405038 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0403737 |
| AREG | amphiregulin | -0.0400585 |
| TMEM62 | transmembrane protein 62 | -0.0400055 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0398745 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0395059 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0385005 |
| MKI67 | marker of proliferation Ki-67 | -0.0375805 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0375705 |
| FMN1 | formin 1 | -0.0375012 |
| BRCA2 | breast cancer 2, early onset | -0.0372801 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0368639 |
| H1-0 | H1.0 linker histone | -0.0360085 |
| RBM39 | RNA binding motif protein 39 | -0.0359615 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0354718 |
| JUN | jun proto-oncogene | -0.035242 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0348964 |
| STK24 | serine/threonine kinase 24 | -0.0348156 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0346517 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0343132 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0328056 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0322573 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0316008 |
| CENPF | centromere protein F, 350/400kDa | -0.0307037 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0303387 |
| XAF1 | XIAP associated factor 1 | -0.0294894 |
| MECOM | MDS1 and EVI1 complex locus | -0.0293822 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0292505 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0290926 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0289205 |
| NF1 | neurofibromin 1 | -0.0284928 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0283041 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0282538 |
| MX2 | MX dynamin-like GTPase 2 | -0.0277932 |
| FNIP1 | folliculin interacting protein 1 | -0.0277286 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0277271 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0271281 |
| XDH | xanthine dehydrogenase | -0.0269568 |
| RAD51B | RAD51 paralog B | -0.0269402 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0267383 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0266092 |
| PTMA | prothymosin, alpha | -0.0257347 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0256248 |
| USP54 | ubiquitin specific peptidase 54 | -0.0254821 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0254208 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0252342 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0252265 |
| LMAN1 | lectin, mannose-binding, 1 | -0.025027 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0248423 |
| KIF13B | kinesin family member 13B | -0.0248395 |
| APOL6 | apolipoprotein L, 6 | -0.0246363 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0243852 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0235287 |
| OCLN | occludin | -0.0234438 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0234204 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0232503 |
| RBBP6 | retinoblastoma binding protein 6 | -0.022777 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0226254 |
| YTHDC1 | YTH domain containing 1 | -0.0225883 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0221595 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0221359 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0221184 |
| THOC2 | THO complex 2 | -0.0216582 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0215195 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0214611 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0211775 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0209558 |
| FOXO3 | forkhead box O3 | -0.020927 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0206133 |
