| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Amsacrine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Amsacrine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.138152 |
| H1-0 | H1.0 linker histone | 0.0948223 |
| LMO7 | LIM domain 7 | 0.0864846 |
| FAT1 | FAT atypical cadherin 1 | 0.0588033 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0573089 |
| DSPP | dentin sialophosphoprotein | 0.0523434 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0501843 |
| EZR | ezrin | 0.0462169 |
| RPL35A | ribosomal protein L35a | 0.0461462 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0456452 |
| DSG2 | desmoglein 2 | 0.0398352 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0394054 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0365432 |
| NDRG1 | N-myc downstream regulated 1 | 0.0352377 |
| MYO1E | myosin IE | 0.0350196 |
| TXNIP | thioredoxin interacting protein | 0.0346054 |
| KRT18 | keratin 18, type I | 0.0336763 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0330883 |
| LOC112694756 | uncharaterized LOC112694756 | 0.032091 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0319166 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0307886 |
| RNF145 | ring finger protein 145 | 0.0305391 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.030494 |
| ANXA1 | annexin A1 | 0.0302892 |
| RIGI | RNA sensor RIG-I | 0.0302679 |
| CENPF | centromere protein F, 350/400kDa | 0.030245 |
| RLF | rearranged L-myc fusion | 0.0298983 |
| PLEC | plectin | 0.0298965 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0296898 |
| EREG | epiregulin | 0.0295839 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0292588 |
| TNS4 | tensin 4 | 0.0287759 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0287195 |
| FAM13A | family with sequence similarity 13, member A | 0.0276916 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0273159 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0272189 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0270665 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0262415 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0259973 |
| CD44 | CD44 molecule (Indian blood group) | 0.0258057 |
| VEGFA | vascular endothelial growth factor A | 0.0248491 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0248241 |
| FNBP1L | formin binding protein 1-like | 0.0244126 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0243459 |
| SNX9 | sorting nexin 9 | 0.0236189 |
| HMGA1 | high mobility group AT-hook 1 | 0.0229304 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0217931 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0213359 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0212332 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0205711 |
| WDR45B | WD repeat domain 45B | 0.0204163 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0203501 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0201964 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0200525 |
| CD109 | CD109 molecule | 0.0199698 |
| SMAD2 | SMAD family member 2 | 0.019915 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.019865 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0196377 |
| EMP1 | epithelial membrane protein 1 | 0.0195032 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0194577 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0194304 |
| TMEM123 | transmembrane protein 123 | 0.0191735 |
| CD2AP | CD2-associated protein | 0.0189188 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0188038 |
| FBXO11 | F-box protein 11 | 0.0184895 |
| FN1 | fibronectin 1 | 0.01845 |
| TLK1 | tousled-like kinase 1 | 0.0183997 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0181885 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0181473 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0180019 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0178212 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0177999 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.017761 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0177569 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0176731 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0175399 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0175304 |
| USP3 | ubiquitin specific peptidase 3 | 0.0174986 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0172715 |
| PGK1 | phosphoglycerate kinase 1 | 0.017266 |
| DNM2 | dynamin 2 | 0.0172164 |
| ABHD2 | abhydrolase domain containing 2 | 0.0169463 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0167459 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0167134 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0166741 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0166295 |
| SEPTIN7 | septin 7 | 0.0165425 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0163945 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0163826 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0163206 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0161311 |
| GDF15 | growth differentiation factor 15 | 0.0160364 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0159936 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0159607 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.0158991 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0158772 |
| MXI1 | MAX interactor 1, dimerization protein | 0.015877 |
| TPI1 | triosephosphate isomerase 1 | 0.0157958 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0157339 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0156612 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.176381 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.122958 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.116365 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.106809 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.106772 |
| RPS27A | ribosomal protein S27a | -0.0957766 |
| RPS12 | ribosomal protein S12 | -0.0920165 |
| TMSB10 | thymosin beta 10 | -0.0876655 |
| UBC | ubiquitin C | -0.0860186 |
| VCL | vinculin | -0.0835796 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0774787 |
| FHIT | fragile histidine triad | -0.0746752 |
| CALR | calreticulin | -0.0728614 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.07281 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0703136 |
| AHNAK | AHNAK nucleoprotein | -0.0661607 |
| PCBP2 | poly(rC) binding protein 2 | -0.0659596 |
| ACTN4 | actinin, alpha 4 | -0.0646805 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0628827 |
| S100A6 | S100 calcium binding protein A6 | -0.0619398 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0618349 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0601088 |
| RPL26 | ribosomal protein L26 | -0.0583612 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0578656 |
| SMYD3 | SET and MYND domain containing 3 | -0.0556658 |
| FLNB | filamin B, beta | -0.0552198 |
| PTEN | phosphatase and tensin homolog | -0.0537591 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0529037 |
| RPS3 | ribosomal protein S3 | -0.0526511 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0521248 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0518045 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0514637 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0513565 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0506155 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0485891 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0474933 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.04685 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0461821 |
| RPL23 | ribosomal protein L23 | -0.045638 |
| CANX | calnexin | -0.0454222 |
| GPHN | gephyrin | -0.0450559 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0449374 |
| RPS8 | ribosomal protein S8 | -0.0448618 |
| DIAPH2 | diaphanous-related formin 2 | -0.044535 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0438296 |
| VMP1 | vacuole membrane protein 1 | -0.043518 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0435098 |
| ASPH | aspartate beta-hydroxylase | -0.0433598 |
| EXOC4 | exocyst complex component 4 | -0.0423261 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0420674 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0420482 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0419849 |
| PRELID2 | PRELI domain containing 2 | -0.0419079 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0410927 |
| ENO1 | enolase 1, (alpha) | -0.0403095 |
| ATXN1 | ataxin 1 | -0.0402665 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0401492 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0392677 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0389645 |
| RAD51B | RAD51 paralog B | -0.0386592 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0385204 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0384427 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0382978 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0378106 |
| RPS6 | ribosomal protein S6 | -0.0373551 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0371337 |
| DENND1A | DENN/MADD domain containing 1A | -0.0370309 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0365439 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0363279 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.036205 |
| SBF2 | SET binding factor 2 | -0.0361306 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0357338 |
| RPL9 | ribosomal protein L9 | -0.0356719 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0355232 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0355199 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0353281 |
| LAMA4 | laminin, alpha 4 | -0.0352877 |
| NEBL | nebulette | -0.0348676 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.034685 |
| RPLP2 | ribosomal protein, large, P2 | -0.034609 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0344949 |
| GOLGA4 | golgin A4 | -0.0340304 |
| PKM | pyruvate kinase, muscle | -0.0336963 |
| MYO1D | myosin ID | -0.0334475 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0333633 |
| FRMD5 | FERM domain containing 5 | -0.0333555 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0327519 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0325729 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0325414 |
| RIN2 | Ras and Rab interactor 2 | -0.0320187 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0314193 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0312855 |
| RPS2 | ribosomal protein S2 | -0.0309399 |
| MAP4 | microtubule-associated protein 4 | -0.0308228 |
| PDLIM5 | PDZ and LIM domain 5 | -0.030701 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0305452 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0302425 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0299919 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0299548 |
| RPS19 | ribosomal protein S19 | -0.0298952 |
