| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Amsacrine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Amsacrine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.102429 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0708893 |
| SMAD3 | SMAD family member 3 | 0.0707141 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0647957 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0613016 |
| TGM2 | transglutaminase 2 | 0.0595803 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0581674 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0571316 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0549025 |
| EFNA5 | ephrin-A5 | 0.0488363 |
| FAM20C | family with sequence similarity 20, member C | 0.0411652 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0400564 |
| EGFR | epidermal growth factor receptor | 0.0387652 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0381954 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0374467 |
| NAV2 | neuron navigator 2 | 0.034369 |
| ATXN1 | ataxin 1 | 0.0331396 |
| INTS6 | integrator complex subunit 6 | 0.032804 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0313689 |
| PLEC | plectin | 0.0308091 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0306552 |
| SEPTIN9 | septin 9 | 0.0306516 |
| VEGFA | vascular endothelial growth factor A | 0.0299922 |
| HMGA2 | high mobility group AT-hook 2 | 0.027835 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0261373 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0257788 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0256003 |
| IFI44L | interferon-induced protein 44-like | 0.0245909 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0238271 |
| MYO10 | myosin X | 0.0226506 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0224192 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0218514 |
| HDAC4 | histone deacetylase 4 | 0.0218505 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0217877 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0216802 |
| ECE1 | endothelin converting enzyme 1 | 0.0212963 |
| ZNF638 | zinc finger protein 638 | 0.0212575 |
| KSR1 | kinase suppressor of ras 1 | 0.021154 |
| DOCK5 | dedicator of cytokinesis 5 | 0.021027 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0206947 |
| RUNX1 | runt-related transcription factor 1 | 0.0206502 |
| CEP250 | centrosomal protein 250kDa | 0.0205768 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0202925 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0202006 |
| RAD51B | RAD51 paralog B | 0.0201869 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0201305 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.019964 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0196569 |
| MX1 | MX dynamin-like GTPase 1 | 0.0191546 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0189582 |
| MCL1 | myeloid cell leukemia 1 | 0.0187801 |
| KYNU | kynureninase | 0.0184706 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.01845 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0180233 |
| NABP1 | nucleic acid binding protein 1 | 0.0179041 |
| STK38L | serine/threonine kinase 38 like | 0.0173033 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0172739 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0171323 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0170252 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0168573 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0167853 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0164968 |
| NRG1 | neuregulin 1 | 0.0164457 |
| CAPRIN2 | caprin family member 2 | 0.016286 |
| RNF213 | ring finger protein 213 | 0.0162111 |
| FLNA | filamin A, alpha | 0.0161964 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0160916 |
| PTK2 | protein tyrosine kinase 2 | 0.0160069 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0159057 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0157832 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0157065 |
| FAM219A | family with sequence similarity 219, member A | 0.0156939 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0154734 |
| NOTCH2 | notch 2 | 0.0154516 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0152138 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0151851 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0150276 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0149797 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0149187 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0148922 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0147402 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0146586 |
| GPHN | gephyrin | 0.0146034 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0146019 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0144949 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.014243 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0141576 |
| KIAA1217 | KIAA1217 | 0.0141202 |
| RARB | retinoic acid receptor, beta | 0.0141006 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0140959 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0140289 |
| HEATR5A | HEAT repeat containing 5A | 0.0140256 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0140218 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0139912 |
| DOCK4 | dedicator of cytokinesis 4 | 0.013877 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0138624 |
| PRKCE | protein kinase C, epsilon | 0.013779 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0137616 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0137503 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0136505 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.269864 |
| VIM | vimentin | -0.254902 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.221605 |
| FTL | ferritin, light polypeptide | -0.114904 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.112168 |
| PTMA | prothymosin, alpha | -0.101557 |
| S100A6 | S100 calcium binding protein A6 | -0.0866341 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0859035 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0837725 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.082777 |
| GOLGA4 | golgin A4 | -0.079649 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0778207 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0725691 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0715819 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0691205 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0686249 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0678418 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0662566 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0657693 |
| LOX | lysyl oxidase | -0.0642313 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.064159 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0608157 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0606884 |
| FN1 | fibronectin 1 | -0.0606853 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0603862 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0586202 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0582089 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0556604 |
| CD44 | CD44 molecule (Indian blood group) | -0.0555707 |
| B2M | beta-2-microglobulin | -0.0545325 |
| RPLP1 | ribosomal protein, large, P1 | -0.0540261 |
| RPL35A | ribosomal protein L35a | -0.0536838 |
| RPS19 | ribosomal protein S19 | -0.0520832 |
| STC1 | stanniocalcin 1 | -0.0517082 |
| MT2A | metallothionein 2A | -0.0516535 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0508155 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0502834 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0490878 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0490399 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0484437 |
| IER3 | immediate early response 3 | -0.0484159 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0471214 |
| RBM39 | RNA binding motif protein 39 | -0.0469036 |
| RPS21 | ribosomal protein S21 | -0.0466231 |
| ENO1 | enolase 1, (alpha) | -0.0461542 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0453015 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0436933 |
| S100A10 | S100 calcium binding protein A10 | -0.0436552 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0427959 |
| RPL34 | ribosomal protein L34 | -0.0417256 |
| NDRG1 | N-myc downstream regulated 1 | -0.0410409 |
| USP34 | ubiquitin specific peptidase 34 | -0.0405425 |
| MEF2A | myocyte enhancer factor 2A | -0.039493 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0391413 |
| GPC6 | glypican 6 | -0.0387807 |
| RIOK3 | RIO kinase 3 | -0.0381691 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0380912 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0376644 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0375683 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0375112 |
| EGR1 | early growth response 1 | -0.037252 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0371511 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0369596 |
| RPLP2 | ribosomal protein, large, P2 | -0.0361197 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0361162 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0360937 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0360867 |
| TMSB4X | thymosin beta 4, X-linked | -0.0360134 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0359833 |
| OSMR | oncostatin M receptor | -0.035924 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0351226 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0348446 |
| RPL32 | ribosomal protein L32 | -0.0346362 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.03366 |
| PGK1 | phosphoglycerate kinase 1 | -0.0335107 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0334286 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0331886 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0328678 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0327749 |
| RPS24 | ribosomal protein S24 | -0.0327667 |
| SNX9 | sorting nexin 9 | -0.0327171 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0325709 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0324946 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0324676 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0320762 |
| RPS8 | ribosomal protein S8 | -0.031738 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0317076 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0314069 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.031324 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0308796 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0308242 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0306635 |
| RPL36 | ribosomal protein L36 | -0.0305725 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0304821 |
| SLC38A1 | solute carrier family 38, member 1 | -0.030096 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0297703 |
| OXSR1 | oxidative stress responsive 1 | -0.0297414 |
| RPS6 | ribosomal protein S6 | -0.0293028 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0292577 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0292312 |
