| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Amsacrine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Amsacrine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.152022 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0738495 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0732235 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0671396 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0529887 |
| NAV2 | neuron navigator 2 | 0.0500558 |
| SVIL | supervillin | 0.0498972 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0482179 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0477826 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0466769 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0465654 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0462054 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0457676 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0450787 |
| RNF145 | ring finger protein 145 | 0.0449225 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0445455 |
| PKM | pyruvate kinase, muscle | 0.0441429 |
| FMNL2 | formin-like 2 | 0.0436364 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0436004 |
| CUL3 | cullin 3 | 0.0420517 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.041416 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0397234 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0395717 |
| ANXA1 | annexin A1 | 0.0392101 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0382784 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0372518 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0370883 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0370132 |
| SMAD3 | SMAD family member 3 | 0.0362902 |
| SQSTM1 | sequestosome 1 | 0.0352363 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0351311 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0350244 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0343932 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0341056 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0340724 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0327948 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0327285 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0326678 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | 0.0324864 |
| HPCAL1 | hippocalcin-like 1 | 0.0321552 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0321307 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0316813 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.030828 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0305806 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0300581 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0295477 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0294577 |
| POTEF | POTE ankyrin domain family, member F | 0.0294032 |
| LDHB | lactate dehydrogenase B | 0.02895 |
| SETD5 | SET domain containing 5 | 0.0287139 |
| COG6 | component of oligomeric golgi complex 6 | 0.0283788 |
| TES | testin LIM domain protein | 0.028191 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0281494 |
| MSN | moesin | 0.0279514 |
| TRRAP | transformation/transcription domain-associated protein | 0.0278765 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0277166 |
| ERBIN | erbb2 interacting protein | 0.0273141 |
| AEBP2 | AE binding protein 2 | 0.0271316 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0268502 |
| FBXO11 | F-box protein 11 | 0.0266732 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0266406 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.026348 |
| ANXA2 | annexin A2 | 0.026281 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0261978 |
| ITGAV | integrin, alpha V | 0.0261586 |
| AHR | aryl hydrocarbon receptor | 0.0260832 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0260703 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.026021 |
| FLNA | filamin A, alpha | 0.0258159 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0257891 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0256191 |
| RUBCN | rubicon autophagy regulator | 0.0255687 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0254384 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0254267 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0252042 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0251953 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0249356 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0248409 |
| INTS6 | integrator complex subunit 6 | 0.0248114 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0246979 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.02467 |
| MAPK14 | mitogen-activated protein kinase 14 | 0.0245839 |
| JMJD1C | jumonji domain containing 1C | 0.0244728 |
| BRD2 | bromodomain containing 2 | 0.0244102 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0243497 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0242965 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0242142 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0242006 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0241742 |
| ZNF638 | zinc finger protein 638 | 0.0240375 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0239698 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0239207 |
| PREPL | prolyl endopeptidase-like | 0.0238279 |
| HELZ | helicase with zinc finger | 0.0235508 |
| CAPRIN2 | caprin family member 2 | 0.0233344 |
| PLEC | plectin | 0.0232735 |
| ARCN1 | archain 1 | 0.0231781 |
| SLMAP | sarcolemma associated protein | 0.0231303 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0230367 |
| ATXN1 | ataxin 1 | 0.0229906 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0818806 |
| VIM | vimentin | -0.0781643 |
| TMSB10 | thymosin beta 10 | -0.0766869 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0716497 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0712051 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0683935 |
| PTMA | prothymosin, alpha | -0.0670292 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0652689 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0490337 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0482313 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0480616 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0468719 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0465953 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0460231 |
| EGR1 | early growth response 1 | -0.0453693 |
| HDAC9 | histone deacetylase 9 | -0.0448181 |
| SMYD3 | SET and MYND domain containing 3 | -0.0432999 |
| H3-3B | H3.3 histone B | -0.0431678 |
| RAI14 | retinoic acid induced 14 | -0.042618 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0425454 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0422833 |
| EEA1 | early endosome antigen 1 | -0.0413895 |
| HLA-B | major histocompatibility complex, class I, B | -0.0411024 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0405733 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0401131 |
| MT2A | metallothionein 2A | -0.0387179 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0380523 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0378306 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0375321 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0371251 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0364191 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0363195 |
| DTNA | dystrobrevin, alpha | -0.0360816 |
| FNIP1 | folliculin interacting protein 1 | -0.0359667 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0359106 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0350569 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0340606 |
| IGF2 | insulin-like growth factor 2 | -0.0340089 |
| MT1X | metallothionein 1X | -0.0338304 |
| MEMO1 | mediator of cell motility 1 | -0.033698 |
| IER3 | immediate early response 3 | -0.03259 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0317956 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0311786 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0310696 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0310245 |
| RAD51B | RAD51 paralog B | -0.030949 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0306165 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0304635 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0303516 |
| CD44 | CD44 molecule (Indian blood group) | -0.0302998 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0300889 |
| MEF2A | myocyte enhancer factor 2A | -0.0300648 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0298619 |
| ARMH4 | armadillo like helical domain containing 4 | -0.029823 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0296878 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0296346 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0295464 |
| B2M | beta-2-microglobulin | -0.0294617 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0291897 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.029097 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0288133 |
| RPS23 | ribosomal protein S23 | -0.0287512 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0286975 |
| S100A9 | S100 calcium binding protein A9 | -0.0285638 |
| FMN1 | formin 1 | -0.0285017 |
| PGK1 | phosphoglycerate kinase 1 | -0.028458 |
| VCL | vinculin | -0.0280371 |
| RIN2 | Ras and Rab interactor 2 | -0.0274335 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0273702 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0271858 |
| RPL23 | ribosomal protein L23 | -0.0271021 |
| DENND4A | DENN/MADD domain containing 4A | -0.0270747 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0269281 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0268864 |
| OPTN | optineurin | -0.0268199 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0267643 |
| GPC6 | glypican 6 | -0.0267545 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0266728 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0266712 |
| SECISBP2 | SECIS binding protein 2 | -0.0266517 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0266465 |
| SDC4 | syndecan 4 | -0.026505 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0259002 |
| PARD3 | par-3 family cell polarity regulator | -0.0259 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0258795 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0257046 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.02568 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0255785 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0255619 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0254909 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0254716 |
| TRIM56 | tripartite motif containing 56 | -0.0252693 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0249291 |
| ANGPTL4 | angiopoietin-like 4 | -0.024901 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0248627 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0248247 |
| CWC27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae) | -0.0247733 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0247712 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0247565 |
| RPS27A | ribosomal protein S27a | -0.0245796 |
