| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Amsacrine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Amsacrine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.118014 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0927194 |
| FAM13A | family with sequence similarity 13, member A | 0.0630325 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0619836 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0609408 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.060762 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0581266 |
| STC2 | stanniocalcin 2 | 0.0575346 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0493964 |
| MYOF | myoferlin | 0.0490606 |
| FLNA | filamin A, alpha | 0.0481463 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0481041 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0463735 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0461413 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0451806 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0447213 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0435514 |
| PLIN2 | perilipin 2 | 0.0433817 |
| RNF145 | ring finger protein 145 | 0.0426533 |
| VEGFA | vascular endothelial growth factor A | 0.041876 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0407819 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0405692 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0403863 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0401004 |
| FLNB | filamin B, beta | 0.0376306 |
| AHNAK | AHNAK nucleoprotein | 0.0365823 |
| SFTPA2 | surfactant protein A2 | 0.0362517 |
| PLEC | plectin | 0.0356558 |
| INTS6 | integrator complex subunit 6 | 0.0351162 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0340414 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0337857 |
| PTK2 | protein tyrosine kinase 2 | 0.0329193 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0327119 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0323411 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0320248 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0304313 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0302416 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0302033 |
| RYBP | RING1 and YY1 binding protein | 0.029821 |
| FMNL2 | formin-like 2 | 0.0294811 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0292215 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268828 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0267526 |
| LMNA | lamin A/C | 0.0264296 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0258933 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0256355 |
| FOSL1 | FOS-like antigen 1 | 0.0255784 |
| RASAL2 | RAS protein activator like 2 | 0.0253795 |
| CTBP2 | C-terminal binding protein 2 | 0.0252636 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0250702 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0249234 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0246633 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0242311 |
| SIRT1 | sirtuin 1 | 0.0233902 |
| EZR | ezrin | 0.0231969 |
| YAP1 | Yes-associated protein 1 | 0.0231123 |
| ANXA5 | annexin A5 | 0.0230852 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0230361 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0228156 |
| RIOK3 | RIO kinase 3 | 0.0226099 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0222198 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0220887 |
| LOXL2 | lysyl oxidase-like 2 | 0.0220641 |
| INSIG2 | insulin induced gene 2 | 0.0218224 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0217308 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0214075 |
| MCL1 | myeloid cell leukemia 1 | 0.0212376 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0211628 |
| HELZ | helicase with zinc finger | 0.0210683 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0209909 |
| DSTN | destrin (actin depolymerizing factor) | 0.0209052 |
| IDS | iduronate 2-sulfatase | 0.0205574 |
| FERMT2 | fermitin family member 2 | 0.0205215 |
| PER1 | period circadian clock 1 | 0.0204919 |
| CD109 | CD109 molecule | 0.0199552 |
| LYST | lysosomal trafficking regulator | 0.0197677 |
| XPO1 | exportin 1 | 0.0194593 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0190787 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0190426 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0189736 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.018776 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0187149 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0184674 |
| ENO1 | enolase 1, (alpha) | 0.0184005 |
| TPM3 | tropomyosin 3 | 0.0183175 |
| CADM1 | cell adhesion molecule 1 | 0.0183117 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0182502 |
| MYO1B | myosin IB | 0.0180237 |
| IRS2 | insulin receptor substrate 2 | 0.0179982 |
| AEBP2 | AE binding protein 2 | 0.0178523 |
| ANXA2 | annexin A2 | 0.0178292 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.017746 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.017733 |
| FAM193B | family with sequence similarity 193, member B | 0.0175521 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0174303 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0173768 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0170897 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0169311 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0168672 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0168305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.378812 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.307831 |
| ITGA1 | integrin, alpha 1 | -0.122737 |
| FN1 | fibronectin 1 | -0.0980774 |
| NRG1 | neuregulin 1 | -0.097652 |
| OSMR | oncostatin M receptor | -0.0969741 |
| GLIS3 | GLIS family zinc finger 3 | -0.0942331 |
| TMEM156 | transmembrane protein 156 | -0.0814229 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0798445 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.075616 |
| SQSTM1 | sequestosome 1 | -0.0739195 |
| SYT1 | synaptotagmin I | -0.0681308 |
| ETV1 | ets variant 1 | -0.0632672 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0606949 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0603409 |
| NRP1 | neuropilin 1 | -0.0588878 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0547499 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0542645 |
| ASPH | aspartate beta-hydroxylase | -0.0539892 |
| VCL | vinculin | -0.0527491 |
| ETV6 | ets variant 6 | -0.0522031 |
| KLHL5 | kelch-like family member 5 | -0.0512291 |
| FOXP1 | forkhead box P1 | -0.0479014 |
| PELO | pelota homolog (Drosophila) | -0.0470189 |
| TMSB10 | thymosin beta 10 | -0.0460633 |
| EFNA5 | ephrin-A5 | -0.0450326 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0444818 |
| SMOX | spermine oxidase | -0.0444169 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0435178 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0433372 |
| CENPF | centromere protein F, 350/400kDa | -0.0428179 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0415696 |
| RUNX2 | runt-related transcription factor 2 | -0.0404485 |
| MKI67 | marker of proliferation Ki-67 | -0.0397288 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0391821 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0390416 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0389881 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.038522 |
| SSH1 | slingshot protein phosphatase 1 | -0.0385021 |
| HLA-B | major histocompatibility complex, class I, B | -0.0377053 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0374524 |
| TOP1 | topoisomerase (DNA) I | -0.0373037 |
| CD44 | CD44 molecule (Indian blood group) | -0.0371583 |
| TPR | translocated promoter region, nuclear basket protein | -0.0366182 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0360069 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.035363 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0347977 |
| FNBP1 | formin binding protein 1 | -0.0340386 |
| FAF2 | Fas associated factor family member 2 | -0.033674 |
| NTN4 | netrin 4 | -0.0332257 |
| VMP1 | vacuole membrane protein 1 | -0.0329837 |
| CAB39 | calcium binding protein 39 | -0.0324832 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0324374 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0320958 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0316115 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0314595 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0306001 |
| AOPEP | aminopeptidase O (putative) | -0.030575 |
| RRBP1 | ribosome binding protein 1 | -0.0299813 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0296587 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0296064 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0291072 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0281422 |
| ITGB5 | integrin, beta 5 | -0.0280612 |
| ETNK1 | ethanolamine kinase 1 | -0.0279033 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0278594 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0275391 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0274693 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0274308 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0269968 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0267127 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.026684 |
| EREG | epiregulin | -0.0266084 |
| HPCAL1 | hippocalcin-like 1 | -0.0264811 |
| ADD3 | adducin 3 (gamma) | -0.0263083 |
| CCDC91 | coiled-coil domain containing 91 | -0.0262648 |
| TPM4 | tropomyosin 4 | -0.0262311 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0260705 |
| RAB31 | RAB31, member RAS oncogene family | -0.0256863 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0256032 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0253128 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0253076 |
| CDCP1 | CUB domain containing protein 1 | -0.0250227 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0249229 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0248038 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0244637 |
| EGR1 | early growth response 1 | -0.0241604 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0241296 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0240831 |
| TMEM131 | transmembrane protein 131 | -0.0237154 |
| S100A6 | S100 calcium binding protein A6 | -0.0236986 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0236915 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0232187 |
| TMSB4X | thymosin beta 4, X-linked | -0.0229826 |
| SYNJ2 | synaptojanin 2 | -0.0229184 |
| FMN1 | formin 1 | -0.0227086 |
| RTN4 | reticulon 4 | -0.0226609 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0226591 |
| SMIM14 | small integral membrane protein 14 | -0.0226344 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0223969 |
