Amyloidosis Gene Set

Dataset DISEASES Curated Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An acquired metabolic disease that involves abnormal deposited of amyloid proteins in organs and/or tissues. (Human Disease Ontology, DOID_9120)
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Genes

70 genes involed in the disease Amyloidosis from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ACTA2 actin, alpha 2, smooth muscle, aorta 4.0
ACTG1 actin gamma 1 4.0
CLU clusterin 4.0
AZGP1 alpha-2-glycoprotein 1, zinc-binding 4.0
APOA2 apolipoprotein A-II 4.0
APOA4 apolipoprotein A-IV 4.0
TGFBI transforming growth factor, beta-induced, 68kDa 4.0
INS insulin 4.0
HBZ hemoglobin, zeta 4.0
HBB hemoglobin, beta 4.0
FN1 fibronectin 1 4.0
DBN1 drebrin 1 4.0
LGALS7 lectin, galactoside-binding, soluble, 7 4.0
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 4.0
OSMR oncostatin M receptor 4.0
SDC3 syndecan 3 4.0
TREM2 triggering receptor expressed on myeloid cells 2 4.0
ALB albumin 4.0
APCS amyloid P component, serum 4.0
TTR transthyretin 4.0
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 4.0
LAMA1 laminin, alpha 1 4.0
CST3 cystatin C 4.0
C3 complement component 3 4.0
C9 complement component 9 4.0
SAA1 serum amyloid A1 4.0
SAA2 serum amyloid A2 4.0
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 4.0
GSN gelsolin 4.0
LECT2 leukocyte cell-derived chemotaxin 2 4.0
A2M alpha-2-macroglobulin 4.0
TACSTD2 tumor-associated calcium signal transducer 2 4.0
IL31RA interleukin 31 receptor A 4.0
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 4.0
SDC2 syndecan 2 4.0
SDC1 syndecan 1 4.0
APP amyloid beta (A4) precursor protein 4.0
B2M beta-2-microglobulin 4.0
ITM2B integral membrane protein 2B 4.0
HSPG2 heparan sulfate proteoglycan 2 4.0
MEFV Mediterranean fever 4.0
APOC3 apolipoprotein C-III 4.0
APOC2 apolipoprotein C-II 4.0
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 4.0
LACRT lacritin 4.0
FGA fibrinogen alpha chain 4.0
LYZ lysozyme 4.0
DCD dermcidin 4.0
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 4.0
GPC1 glypican 1 4.0
ADAM10 ADAM metallopeptidase domain 10 4.0
TM2D3 TM2 domain containing 3 4.0
MFGE8 milk fat globule-EGF factor 8 protein 4.0
SEMG1 semenogelin I 4.0
PPP5C protein phosphatase 5, catalytic subunit 4.0
APOA1 apolipoprotein A-I 4.0
PSEN1 presenilin 1 4.0
PSEN2 presenilin 2 4.0
NLRP3 NLR family, pyrin domain containing 3 4.0
GPNMB glycoprotein (transmembrane) nmb 4.0
ACTB actin, beta 4.0
AGRN agrin 4.0
PRNP prion protein 4.0
KRT14 keratin 14, type I 4.0
APOE apolipoprotein E 4.0
ODAM odontogenic, ameloblast asssociated 4.0
KRT5 keratin 5, type II 4.0
KRT1 keratin 1, type II 4.0
NPPA natriuretic peptide A 4.0
UNC5C unc-5 homolog C (C. elegans) 4.0