| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anastrozole perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anastrozole_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.208472 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.183737 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.180448 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.153336 |
| AHNAK | AHNAK nucleoprotein | 0.12133 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.101206 |
| TMSB4X | thymosin beta 4, X-linked | 0.0867252 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0848624 |
| CALR | calreticulin | 0.0828446 |
| TPM3 | tropomyosin 3 | 0.0814378 |
| CENPF | centromere protein F, 350/400kDa | 0.0798681 |
| DSPP | dentin sialophosphoprotein | 0.0758262 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0726563 |
| ASPH | aspartate beta-hydroxylase | 0.0670744 |
| HDAC9 | histone deacetylase 9 | 0.0667887 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0665307 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0663172 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0661154 |
| FLNA | filamin A, alpha | 0.0659179 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0639196 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.063893 |
| MSN | moesin | 0.0608494 |
| PRSS23 | protease, serine, 23 | 0.0603278 |
| DST | dystonin | 0.0597109 |
| PLEC | plectin | 0.0574197 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0564385 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0564241 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0557428 |
| FSTL1 | follistatin-like 1 | 0.053697 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0530001 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0514516 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0504896 |
| RPS2 | ribosomal protein S2 | 0.0497355 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0492488 |
| SET | SET nuclear proto-oncogene | 0.047385 |
| ENO1 | enolase 1, (alpha) | 0.0448405 |
| APP | amyloid beta (A4) precursor protein | 0.0437861 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0423455 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.042165 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0417452 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0415503 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0414881 |
| PKM | pyruvate kinase, muscle | 0.041308 |
| RPS3 | ribosomal protein S3 | 0.041033 |
| B2M | beta-2-microglobulin | 0.0403579 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0402742 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.040148 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0392787 |
| MT2A | metallothionein 2A | 0.0392339 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0386288 |
| RPL37A | ribosomal protein L37a | 0.0370904 |
| RPL23 | ribosomal protein L23 | 0.0365349 |
| RPS12 | ribosomal protein S12 | 0.036492 |
| SON | SON DNA binding protein | 0.036194 |
| ANXA1 | annexin A1 | 0.0359226 |
| RPL26 | ribosomal protein L26 | 0.035808 |
| CAVIN1 | caveolae associated protein 1 | 0.0357295 |
| TPI1 | triosephosphate isomerase 1 | 0.0352323 |
| EZR | ezrin | 0.0351403 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0348655 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0346786 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0344395 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0343447 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0339977 |
| SQSTM1 | sequestosome 1 | 0.0338236 |
| RND3 | Rho family GTPase 3 | 0.03224 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0318799 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0318421 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0315297 |
| RPL35 | ribosomal protein L35 | 0.0313713 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0313692 |
| SEPTIN7 | septin 7 | 0.0308333 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0307906 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.030729 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0303741 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0299823 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.029851 |
| RRBP1 | ribosome binding protein 1 | 0.0295532 |
| CANX | calnexin | 0.0290516 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0286677 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0286295 |
| RPS6 | ribosomal protein S6 | 0.0282239 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0282069 |
| FAT1 | FAT atypical cadherin 1 | 0.0276268 |
| EGFR | epidermal growth factor receptor | 0.0274886 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0273541 |
| SEPTIN9 | septin 9 | 0.0272708 |
| GOLGB1 | golgin B1 | 0.0265994 |
| RACK1 | receptor for activated C kinase 1 | 0.0265244 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0263228 |
| HSPA8 | heat shock 70kDa protein 8 | 0.025916 |
| MKI67 | marker of proliferation Ki-67 | 0.0258727 |
| HMGB2 | high mobility group box 2 | 0.0258168 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0256495 |
| RPS8 | ribosomal protein S8 | 0.025548 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0254167 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0253267 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0252779 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0250842 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0249303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195504 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.184346 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.130951 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.12228 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.101194 |
| NDRG1 | N-myc downstream regulated 1 | -0.0938093 |
| COL1A2 | collagen, type I, alpha 2 | -0.0844616 |
| LOX | lysyl oxidase | -0.076671 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0759791 |
| FBN1 | fibrillin 1 | -0.0741516 |
| LOXL2 | lysyl oxidase-like 2 | -0.0678701 |
| VIM | vimentin | -0.0654348 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0643027 |
| CD99 | CD99 molecule | -0.0626578 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0599651 |
| AUTS2 | autism susceptibility candidate 2 | -0.0589289 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0557833 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0556338 |
| SUCNR1 | succinate receptor 1 | -0.0552358 |
| PLAT | plasminogen activator, tissue | -0.0522096 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0517711 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0508012 |
| NAV1 | neuron navigator 1 | -0.0496251 |
| UBC | ubiquitin C | -0.0478225 |
| S100A6 | S100 calcium binding protein A6 | -0.047584 |
| PODXL | podocalyxin-like | -0.046944 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.04542 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0445754 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0442678 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0430792 |
| SBF2 | SET binding factor 2 | -0.0416955 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0404144 |
| MSI2 | musashi RNA-binding protein 2 | -0.0401903 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0400919 |
| GPC6 | glypican 6 | -0.0399098 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0398208 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0396688 |
| MEIS2 | Meis homeobox 2 | -0.0396006 |
| HLA-B | major histocompatibility complex, class I, B | -0.0381802 |
| RTN4 | reticulon 4 | -0.0379536 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0377856 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0377296 |
| TAGLN2 | transgelin 2 | -0.0364196 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0361159 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0360722 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0356334 |
| HLA-C | major histocompatibility complex, class I, C | -0.0352279 |
| S100A10 | S100 calcium binding protein A10 | -0.0344085 |
| USP34 | ubiquitin specific peptidase 34 | -0.0328022 |
| MYADM | myeloid-associated differentiation marker | -0.0322906 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0322741 |
| MX2 | MX dynamin-like GTPase 2 | -0.031761 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0314046 |
| MAP4 | microtubule-associated protein 4 | -0.0312678 |
| ANXA2 | annexin A2 | -0.0311139 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0308129 |
| SP3 | Sp3 transcription factor | -0.0305004 |
| COL5A2 | collagen, type V, alpha 2 | -0.0304229 |
| POTEF | POTE ankyrin domain family, member F | -0.029888 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0293895 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0293423 |
| RAB1A | RAB1A, member RAS oncogene family | -0.028607 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0285614 |
| SETD5 | SET domain containing 5 | -0.0283201 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0278457 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0275992 |
| ATP13A3 | ATPase type 13A3 | -0.0272168 |
| COL3A1 | collagen, type III, alpha 1 | -0.027046 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0269802 |
| BSG | basigin (Ok blood group) | -0.0268513 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0267349 |
| PXDN | peroxidasin | -0.026706 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0262857 |
| FTL | ferritin, light polypeptide | -0.0262001 |
| CTSB | cathepsin B | -0.0257262 |
| FN1 | fibronectin 1 | -0.0253584 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.025199 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.025194 |
| KRT81 | keratin 81, type II | -0.0249519 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0249116 |
| HELZ | helicase with zinc finger | -0.024907 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0248478 |
| HIP1 | huntingtin interacting protein 1 | -0.0248069 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0247976 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0246783 |
| RUNX1 | runt-related transcription factor 1 | -0.0246637 |
| PFN1 | profilin 1 | -0.0244952 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0243187 |
| CUX1 | cut-like homeobox 1 | -0.023882 |
| PRKD3 | protein kinase D3 | -0.0236924 |
| TAPBP | TAP binding protein (tapasin) | -0.0236906 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0235806 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0235575 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0228441 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0227825 |
| TMEM165 | transmembrane protein 165 | -0.0227738 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0225032 |
| COL1A1 | collagen, type I, alpha 1 | -0.02243 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0222483 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0222117 |
