| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anastrozole perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anastrozole_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.173422 |
| FMN1 | formin 1 | 0.165459 |
| TLE4 | transducin-like enhancer of split 4 | 0.141626 |
| LSAMP | limbic system-associated membrane protein | 0.112138 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0879629 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0845681 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0815603 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0805702 |
| RNF213 | ring finger protein 213 | 0.0782034 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0742251 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0736948 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.071998 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0710392 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0688947 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0685574 |
| DST | dystonin | 0.0659393 |
| KLHL13 | kelch-like family member 13 | 0.0655329 |
| GLCCI1 | glucocorticoid induced 1 | 0.0645687 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0622855 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0619835 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0618979 |
| ACTG1 | actin gamma 1 | 0.0611221 |
| BPTF | bromodomain PHD finger transcription factor | 0.0602738 |
| PLPP1 | phospholipid phosphatase 1 | 0.0600842 |
| SYT1 | synaptotagmin I | 0.0544915 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0520971 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0517916 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.051619 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0504591 |
| THBS1 | thrombospondin 1 | 0.0504456 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0496758 |
| FAM107B | family with sequence similarity 107, member B | 0.0494281 |
| SIK2 | salt-inducible kinase 2 | 0.0484615 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0466742 |
| RIGI | RNA sensor RIG-I | 0.0464917 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0461051 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0446661 |
| MEIS2 | Meis homeobox 2 | 0.0439552 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0423292 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0420295 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0417656 |
| EGR1 | early growth response 1 | 0.0416663 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0414141 |
| SP100 | SP100 nuclear antigen | 0.0411265 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0407527 |
| ITGA1 | integrin, alpha 1 | 0.0406247 |
| IGF2 | insulin-like growth factor 2 | 0.039796 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0394748 |
| COL3A1 | collagen, type III, alpha 1 | 0.0386689 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0386573 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0385244 |
| TPM1 | tropomyosin 1 (alpha) | 0.0378773 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0368801 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0365894 |
| AHNAK | AHNAK nucleoprotein | 0.0358761 |
| SMYD3 | SET and MYND domain containing 3 | 0.0355862 |
| VMP1 | vacuole membrane protein 1 | 0.035201 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0349403 |
| RPS2 | ribosomal protein S2 | 0.0347165 |
| RPS6 | ribosomal protein S6 | 0.0345426 |
| STK38L | serine/threonine kinase 38 like | 0.0342936 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0342137 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0341275 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0339044 |
| MRTFA | myocardin related transcription factor A | 0.0336137 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0331625 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.032784 |
| CRH | corticotropin releasing hormone | 0.0321278 |
| TENM4 | teneurin transmembrane protein 4 | 0.032014 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0319821 |
| FERMT2 | fermitin family member 2 | 0.0319026 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0317525 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0316639 |
| PRKCA | protein kinase C, alpha | 0.0314518 |
| PDE10A | phosphodiesterase 10A | 0.0314449 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0312165 |
| HOMER1 | homer scaffolding protein 1 | 0.0311917 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0310823 |
| PLAT | plasminogen activator, tissue | 0.031024 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0306432 |
| B2M | beta-2-microglobulin | 0.0305117 |
| MED13 | mediator complex subunit 13 | 0.0302188 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0299681 |
| SEPTIN9 | septin 9 | 0.029727 |
| TPM4 | tropomyosin 4 | 0.0295255 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0294068 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0291309 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0288704 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0286847 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0285329 |
| DGKH | diacylglycerol kinase, eta | 0.028171 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0279558 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0278462 |
| ENAH | enabled homolog (Drosophila) | 0.0277709 |
| VIM | vimentin | 0.027704 |
| NRP1 | neuropilin 1 | 0.0274709 |
| RPL23 | ribosomal protein L23 | 0.0274241 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0273725 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0271608 |
| ACTN1 | actinin, alpha 1 | 0.0270745 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.0416125 |
| DTNA | dystrobrevin, alpha | -0.031402 |
| HELZ | helicase with zinc finger | -0.028371 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0272747 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0266081 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0262991 |
| COPA | coatomer protein complex, subunit alpha | -0.0262595 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0252809 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0246156 |
| GOLGA4 | golgin A4 | -0.0244143 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0243044 |
| USP3 | ubiquitin specific peptidase 3 | -0.023496 |
| GDF15 | growth differentiation factor 15 | -0.0232218 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0229319 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0219101 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0218758 |
| NRG1 | neuregulin 1 | -0.0216848 |
| CDH13 | cadherin 13 | -0.0213555 |
| SRP54 | signal recognition particle 54kDa | -0.0211262 |
| PTK2 | protein tyrosine kinase 2 | -0.020955 |
| HMGA1 | high mobility group AT-hook 1 | -0.0208463 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0208346 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0206741 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0205941 |
| USP34 | ubiquitin specific peptidase 34 | -0.0198909 |
| CADM1 | cell adhesion molecule 1 | -0.0197843 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0192078 |
| RTN4 | reticulon 4 | -0.0191974 |
| FAM13A | family with sequence similarity 13, member A | -0.01898 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0188715 |
| SUCO | SUN domain containing ossification factor | -0.01882 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0183941 |
| QKI | QKI, KH domain containing, RNA binding | -0.0180359 |
| EFNA5 | ephrin-A5 | -0.0176543 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0174849 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0174653 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0174508 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0172039 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0170448 |
| CDC27 | cell division cycle 27 | -0.0170432 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0168796 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0168109 |
| WDR45B | WD repeat domain 45B | -0.0167815 |
| NBAS | neuroblastoma amplified sequence | -0.0167798 |
| DIAPH3 | diaphanous-related formin 3 | -0.0165897 |
| PDE8A | phosphodiesterase 8A | -0.0165468 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0164181 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0161916 |
| BBX | bobby sox homolog (Drosophila) | -0.0161806 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0161407 |
| SEC24A | SEC24 family member A | -0.0161392 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0161032 |
| MEF2A | myocyte enhancer factor 2A | -0.0158369 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0156694 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0150597 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0149674 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0149057 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0148283 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0148076 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0145751 |
| SETD5 | SET domain containing 5 | -0.0145065 |
| CTBP2 | C-terminal binding protein 2 | -0.0144859 |
| MTSS2 | MTSS I-BAR domain containing 2 | -0.0144612 |
| LRRC7 | leucine rich repeat containing 7 | -0.0144379 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0142461 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0142443 |
| NUP58 | nucleoporin 58 | -0.0139834 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0139494 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0139474 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0138716 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0138501 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0137135 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0137115 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0136842 |
| ARF4 | ADP-ribosylation factor 4 | -0.0136512 |
| DYM | dymeclin | -0.0135794 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0133854 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0133575 |
| WRN | Werner syndrome, RecQ helicase-like | -0.0133566 |
| DHFR | dihydrofolate reductase | -0.0133288 |
| RNF24 | ring finger protein 24 | -0.0132595 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0132348 |
| ZNF148 | zinc finger protein 148 | -0.0130314 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0129537 |
| SPAG9 | sperm associated antigen 9 | -0.0129425 |
| GPC5 | glypican 5 | -0.0129058 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0128965 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0128961 |
| MORF4L2 | mortality factor 4 like 2 | -0.0128409 |
| XPO1 | exportin 1 | -0.0127693 |
| SRPK2 | SRSF protein kinase 2 | -0.0127663 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0127501 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0127273 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0126888 |
| SMAP1 | small ArfGAP 1 | -0.0125832 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0125072 |
| RNF150 | ring finger protein 150 | -0.0123218 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0122979 |
| USP15 | ubiquitin specific peptidase 15 | -0.0122978 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0121969 |
