| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anastrozole perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anastrozole_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.351611 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.176372 |
| EXT1 | exostosin glycosyltransferase 1 | 0.149628 |
| SMAD3 | SMAD family member 3 | 0.133424 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.129352 |
| INTS6 | integrator complex subunit 6 | 0.117316 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.11351 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.111291 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.111253 |
| EFNB2 | ephrin-B2 | 0.0861954 |
| DSPP | dentin sialophosphoprotein | 0.0782383 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.075497 |
| RNF213 | ring finger protein 213 | 0.0690955 |
| MYO1E | myosin IE | 0.068848 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0687569 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0685616 |
| AREG | amphiregulin | 0.0674594 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0655012 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0647736 |
| PKM | pyruvate kinase, muscle | 0.0632674 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0608017 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.059472 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0592813 |
| MAP7 | microtubule-associated protein 7 | 0.0592 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0528354 |
| DST | dystonin | 0.0525718 |
| KYNU | kynureninase | 0.0515506 |
| FAT1 | FAT atypical cadherin 1 | 0.0503815 |
| ASPH | aspartate beta-hydroxylase | 0.0498035 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0498001 |
| HKDC1 | hexokinase domain containing 1 | 0.0492211 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0465318 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0455296 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0437605 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0436275 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0417496 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.041082 |
| SEPTIN9 | septin 9 | 0.0407056 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0404674 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0397108 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.039357 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0391644 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0389863 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.03761 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0371237 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0365106 |
| EREG | epiregulin | 0.0360883 |
| EZR | ezrin | 0.0357864 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0342346 |
| ANXA2 | annexin A2 | 0.0339947 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0339523 |
| GOLGB1 | golgin B1 | 0.0339039 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0337489 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0333652 |
| LAMB3 | laminin, beta 3 | 0.0332221 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0331232 |
| PDZD8 | PDZ domain containing 8 | 0.033025 |
| FNIP2 | folliculin interacting protein 2 | 0.0327242 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0324995 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0324583 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.032339 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0322421 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0318533 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0316348 |
| USP53 | ubiquitin specific peptidase 53 | 0.0315156 |
| MYO5B | myosin VB | 0.0314164 |
| IFNGR1 | interferon gamma receptor 1 | 0.0306727 |
| CTBP2 | C-terminal binding protein 2 | 0.0303035 |
| SLK | STE20-like kinase | 0.0300874 |
| ABHD2 | abhydrolase domain containing 2 | 0.0299114 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0297805 |
| TOX3 | TOX high mobility group box family member 3 | 0.0290922 |
| TOP1 | topoisomerase (DNA) I | 0.0289724 |
| SQSTM1 | sequestosome 1 | 0.0287864 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0284768 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0278691 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.027766 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0275889 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0275233 |
| HYOU1 | hypoxia up-regulated 1 | 0.0274481 |
| VCL | vinculin | 0.0271915 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.027148 |
| SET | SET nuclear proto-oncogene | 0.0271077 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0270918 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0270289 |
| CALR | calreticulin | 0.0267275 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0266425 |
| RRBP1 | ribosome binding protein 1 | 0.0264217 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.026245 |
| TXNRD1 | thioredoxin reductase 1 | 0.0260507 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0257874 |
| TJP1 | tight junction protein 1 | 0.025724 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0256976 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0256518 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0252831 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0247664 |
| APP | amyloid beta (A4) precursor protein | 0.024557 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0241014 |
| HOMER1 | homer scaffolding protein 1 | 0.0240592 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.023942 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.132016 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.12338 |
| LYZ | lysozyme | -0.104401 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.102676 |
| HLA-B | major histocompatibility complex, class I, B | -0.0904695 |
| PTMA | prothymosin, alpha | -0.0859062 |
| NDRG1 | N-myc downstream regulated 1 | -0.0838128 |
| TXNIP | thioredoxin interacting protein | -0.0643677 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0617571 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0595251 |
| NPSR1 | neuropeptide S receptor 1 | -0.0578699 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0573547 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0533627 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0512273 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0510491 |
| XAF1 | XIAP associated factor 1 | -0.0509165 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0490393 |
| HLA-C | major histocompatibility complex, class I, C | -0.045908 |
| H1-0 | H1.0 linker histone | -0.0426588 |
| TMSB10 | thymosin beta 10 | -0.0393182 |
| CTSD | cathepsin D | -0.0393051 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0385432 |
| HLA-E | major histocompatibility complex, class I, E | -0.0380402 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0368961 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0366578 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0363314 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0360741 |
| UBC | ubiquitin C | -0.0357631 |
| SSH2 | slingshot protein phosphatase 2 | -0.0350366 |
| S100A6 | S100 calcium binding protein A6 | -0.033853 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0334182 |
| PMP22 | peripheral myelin protein 22 | -0.0330598 |
| RPS24 | ribosomal protein S24 | -0.0330156 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0323331 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0321431 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0320404 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0318175 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0317916 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.031294 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0310768 |
| PERP | PERP, TP53 apoptosis effector | -0.030984 |
| PTEN | phosphatase and tensin homolog | -0.0303255 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0300222 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0295063 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0287324 |
| RPS6 | ribosomal protein S6 | -0.0286281 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0285125 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0284769 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0282985 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0279793 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0278088 |
| HMGB1 | high mobility group box 1 | -0.0274677 |
| NCKAP5 | NCK-associated protein 5 | -0.0271684 |
| RNF149 | ring finger protein 149 | -0.0271617 |
| RPL35A | ribosomal protein L35a | -0.0270464 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0270205 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0269329 |
| PLSCR1 | phospholipid scramblase 1 | -0.0264097 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0256161 |
| RPLP1 | ribosomal protein, large, P1 | -0.025317 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0253082 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0252532 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0250509 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0250488 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0246091 |
| ANXA4 | annexin A4 | -0.0245611 |
| SBF2 | SET binding factor 2 | -0.0244851 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0244822 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0244544 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0244354 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0243261 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0241572 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0241173 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0240743 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0240721 |
| GNAS | GNAS complex locus | -0.0239599 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0238638 |
| VDAC1 | voltage-dependent anion channel 1 | -0.02359 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0235546 |
| MX2 | MX dynamin-like GTPase 2 | -0.0235071 |
| WDR45B | WD repeat domain 45B | -0.0234504 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0232536 |
| EGR1 | early growth response 1 | -0.0230999 |
| CSTB | cystatin B (stefin B) | -0.0230991 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0230028 |
| NF1 | neurofibromin 1 | -0.0225347 |
| TBC1D22A | TBC1 domain family, member 22A | -0.022505 |
| DIAPH3 | diaphanous-related formin 3 | -0.0223157 |
| RBM39 | RNA binding motif protein 39 | -0.0222852 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0218117 |
| EPCAM | epithelial cell adhesion molecule | -0.0217756 |
| FOXP1 | forkhead box P1 | -0.0215983 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0215907 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0214294 |
| TMEM87A | transmembrane protein 87A | -0.0213967 |
| ZNF395 | zinc finger protein 395 | -0.0213739 |
| ZNF292 | zinc finger protein 292 | -0.0212663 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0212618 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0212058 |
| CCDC146 | coiled-coil domain containing 146 | -0.0211541 |
