| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anastrozole perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anastrozole_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.197641 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.148529 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.132735 |
| LMO7 | LIM domain 7 | 0.126914 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.124314 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.122429 |
| DSPP | dentin sialophosphoprotein | 0.11555 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.113261 |
| HYOU1 | hypoxia up-regulated 1 | 0.104502 |
| EZR | ezrin | 0.0930019 |
| PLEC | plectin | 0.0804117 |
| TMSB4X | thymosin beta 4, X-linked | 0.0764958 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0755636 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0747888 |
| ANXA1 | annexin A1 | 0.0683096 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0680973 |
| KRT18 | keratin 18, type I | 0.0652537 |
| GDA | guanine deaminase | 0.0647888 |
| RPS12 | ribosomal protein S12 | 0.0633256 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0629595 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0625603 |
| MYOF | myoferlin | 0.0616713 |
| SEPTIN9 | septin 9 | 0.0607939 |
| ASPH | aspartate beta-hydroxylase | 0.0603784 |
| RPS3 | ribosomal protein S3 | 0.0602155 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0576426 |
| SET | SET nuclear proto-oncogene | 0.0560657 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0558787 |
| RPS2 | ribosomal protein S2 | 0.0555874 |
| TXNRD1 | thioredoxin reductase 1 | 0.0555686 |
| FAT1 | FAT atypical cadherin 1 | 0.0531423 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0525102 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0487377 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.047859 |
| CALR | calreticulin | 0.0475283 |
| GOLGB1 | golgin B1 | 0.047504 |
| AREG | amphiregulin | 0.0469863 |
| B2M | beta-2-microglobulin | 0.0466712 |
| KRT8 | keratin 8, type II | 0.0448645 |
| TPM3 | tropomyosin 3 | 0.0437697 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.042057 |
| TES | testin LIM domain protein | 0.0415702 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0413481 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0403662 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0398532 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0396761 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0386702 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0381883 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0375729 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0372645 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0366303 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0352981 |
| RPL3 | ribosomal protein L3 | 0.0351484 |
| PKM | pyruvate kinase, muscle | 0.0351479 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0350896 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0350809 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.034492 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0344637 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0343553 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0340714 |
| SMAD3 | SMAD family member 3 | 0.0334116 |
| RPL37A | ribosomal protein L37a | 0.0333101 |
| BRD2 | bromodomain containing 2 | 0.0332424 |
| TPI1 | triosephosphate isomerase 1 | 0.033125 |
| ITGA6 | integrin, alpha 6 | 0.0329967 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0328645 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0323996 |
| CPNE1 | copine I | 0.0323688 |
| TMF1 | TATA element modulatory factor 1 | 0.0306691 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0305614 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0299168 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0297896 |
| CLTC | clathrin, heavy chain (Hc) | 0.0297855 |
| DST | dystonin | 0.0296251 |
| CDK6 | cyclin-dependent kinase 6 | 0.0296239 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0296054 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0295321 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0294881 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.029488 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0294596 |
| LRRC59 | leucine rich repeat containing 59 | 0.0293935 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0292775 |
| RPL26 | ribosomal protein L26 | 0.0291508 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0288429 |
| RPS8 | ribosomal protein S8 | 0.0280706 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0272923 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0268713 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0265649 |
| RPS27A | ribosomal protein S27a | 0.0264113 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0262223 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0259743 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0259469 |
| AHNAK | AHNAK nucleoprotein | 0.0253214 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0252313 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0251367 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0250263 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0249611 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0247909 |
| RPL35 | ribosomal protein L35 | 0.0247904 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.024543 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.264346 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.159222 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.146289 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0979821 |
| NDRG1 | N-myc downstream regulated 1 | -0.083743 |
| POTEF | POTE ankyrin domain family, member F | -0.0707604 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0676839 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0659515 |
| TMSB10 | thymosin beta 10 | -0.06388 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0632739 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0585597 |
| RPS25 | ribosomal protein S25 | -0.0580002 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0574797 |
| S100A10 | S100 calcium binding protein A10 | -0.0536255 |
| WDR45B | WD repeat domain 45B | -0.0523945 |
| S100A6 | S100 calcium binding protein A6 | -0.0458381 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.045204 |
| HMGA1 | high mobility group AT-hook 1 | -0.0448659 |
| RPS24 | ribosomal protein S24 | -0.0409948 |
| CLDN7 | claudin 7 | -0.0384397 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0382955 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0375682 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0373036 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0366367 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0355111 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0343058 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0327829 |
| AUTS2 | autism susceptibility candidate 2 | -0.0327626 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0324542 |
| RPL35A | ribosomal protein L35a | -0.0323602 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.032203 |
| INSIG1 | insulin induced gene 1 | -0.0321698 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0321607 |
| PRKCA | protein kinase C, alpha | -0.031803 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0310465 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0309452 |
| HLA-A | major histocompatibility complex, class I, A | -0.0309122 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0306312 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0304638 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0290973 |
| SSH2 | slingshot protein phosphatase 2 | -0.0285689 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0281227 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0279869 |
| RPLP1 | ribosomal protein, large, P1 | -0.0276055 |
| GNAS | GNAS complex locus | -0.0274267 |
| FLNB | filamin B, beta | -0.0272916 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0272274 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0271255 |
| DEK | DEK proto-oncogene | -0.0270653 |
| FASN | fatty acid synthase | -0.0270403 |
| ANLN | anillin, actin binding protein | -0.0268174 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0268013 |
| RHEB | Ras homolog enriched in brain | -0.0266466 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0265206 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0261829 |
| KRT7 | keratin 7, type II | -0.0258955 |
| CCND1 | cyclin D1 | -0.0258509 |
| GPX2 | glutathione peroxidase 2 | -0.0256831 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0256263 |
| PGK1 | phosphoglycerate kinase 1 | -0.0256143 |
| NF1 | neurofibromin 1 | -0.025613 |
| IRF1 | interferon regulatory factor 1 | -0.0254558 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0252496 |
| CD46 | CD46 molecule, complement regulatory protein | -0.025055 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0244083 |
| S100A9 | S100 calcium binding protein A9 | -0.024225 |
| PHF14 | PHD finger protein 14 | -0.0239385 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.023696 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0236728 |
| HMGB1 | high mobility group box 1 | -0.0233871 |
| FDPS | farnesyl diphosphate synthase | -0.0232896 |
| ANXA2 | annexin A2 | -0.0232128 |
| TFF2 | trefoil factor 2 | -0.0230558 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.022949 |
| HLA-B | major histocompatibility complex, class I, B | -0.0228095 |
| MECOM | MDS1 and EVI1 complex locus | -0.0228068 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0227595 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0227119 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0226916 |
| DIAPH2 | diaphanous-related formin 2 | -0.0224615 |
| RAD51B | RAD51 paralog B | -0.0221095 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0218488 |
| CCNL1 | cyclin L1 | -0.0216857 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0215005 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0212098 |
| DENND1A | DENN/MADD domain containing 1A | -0.020975 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0206967 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0206737 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0206123 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0203868 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0203745 |
| DIAPH3 | diaphanous-related formin 3 | -0.0203672 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0203533 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0203416 |
| ZNF609 | zinc finger protein 609 | -0.0203249 |
| RPL28 | ribosomal protein L28 | -0.0201406 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0201076 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0200916 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.020067 |
| LAMA5 | laminin, alpha 5 | -0.0200366 |
