| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anastrozole perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anastrozole_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0996786 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0980419 |
| PKM | pyruvate kinase, muscle | 0.0729129 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0723796 |
| HDAC9 | histone deacetylase 9 | 0.0719125 |
| MKI67 | marker of proliferation Ki-67 | 0.0711162 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0654643 |
| RPL3 | ribosomal protein L3 | 0.0608341 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0545508 |
| CENPF | centromere protein F, 350/400kDa | 0.0529645 |
| ANXA1 | annexin A1 | 0.050812 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0492282 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0442105 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0434435 |
| GLI3 | GLI family zinc finger 3 | 0.042582 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0403185 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0398722 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0392688 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0382833 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0382521 |
| ANLN | anillin, actin binding protein | 0.0375803 |
| NAV2 | neuron navigator 2 | 0.0375048 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0369786 |
| BRD2 | bromodomain containing 2 | 0.0365673 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0365295 |
| PDGFC | platelet derived growth factor C | 0.0349332 |
| TPX2 | TPX2, microtubule-associated | 0.0342583 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0342312 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0337707 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0335198 |
| INTS6 | integrator complex subunit 6 | 0.0327352 |
| FER1L6 | fer-1-like family member 6 | 0.0323168 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0313099 |
| DIAPH3 | diaphanous-related formin 3 | 0.0310744 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0304734 |
| AMOTL2 | angiomotin like 2 | 0.0292193 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0287155 |
| RRM2 | ribonucleotide reductase M2 | 0.0282523 |
| ZNF608 | zinc finger protein 608 | 0.0279698 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0276641 |
| MYO5C | myosin VC | 0.0272715 |
| RPS2 | ribosomal protein S2 | 0.0266074 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0265821 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0261389 |
| H1-4 | H1.4 linker histone, cluster member | 0.0258867 |
| EGFR | epidermal growth factor receptor | 0.025139 |
| TPM3 | tropomyosin 3 | 0.0250873 |
| SEPTIN9 | septin 9 | 0.0247579 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.024543 |
| FOXP1 | forkhead box P1 | 0.0244934 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0242935 |
| DST | dystonin | 0.0236769 |
| SGMS2 | sphingomyelin synthase 2 | 0.0234373 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0233503 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0226957 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0226873 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0220508 |
| CCDC88A | coiled-coil domain containing 88A | 0.0219532 |
| JUN | jun proto-oncogene | 0.0218902 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.021206 |
| KIF11 | kinesin family member 11 | 0.0210742 |
| BMP10 | bone morphogenetic protein 10 | 0.0207907 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.020676 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0206674 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0204534 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0203082 |
| IRS1 | insulin receptor substrate 1 | 0.020264 |
| PRSS23 | protease, serine, 23 | 0.0201749 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0201513 |
| CENPE | centromere protein E, 312kDa | 0.0201502 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0197504 |
| TPI1 | triosephosphate isomerase 1 | 0.0196763 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0195437 |
| MLIP | muscular LMNA-interacting protein | 0.0193624 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0192512 |
| EZR | ezrin | 0.019173 |
| TPM4 | tropomyosin 4 | 0.0189943 |
| MACROD2 | MACRO domain containing 2 | 0.01895 |
| SON | SON DNA binding protein | 0.0187493 |
| PCBP2 | poly(rC) binding protein 2 | 0.0187188 |
| HDGF | hepatoma-derived growth factor | 0.0186982 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0186141 |
| KIF4A | kinesin family member 4A | 0.0185326 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0184673 |
| MCL1 | myeloid cell leukemia 1 | 0.0184024 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0182766 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0182668 |
| FN1 | fibronectin 1 | 0.0182522 |
| AEBP2 | AE binding protein 2 | 0.018164 |
| RSPRY1 | ring finger and SPRY domain containing 1 | 0.0181418 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0181031 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0180711 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0178824 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0178043 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0176068 |
| RPS12 | ribosomal protein S12 | 0.0175828 |
| PDE7B | phosphodiesterase 7B | 0.0174356 |
| LMO7 | LIM domain 7 | 0.0173536 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.017197 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0171842 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.26569 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.172023 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.12718 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.123889 |
| GOLGA4 | golgin A4 | -0.102163 |
| S100A6 | S100 calcium binding protein A6 | -0.0848815 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0733774 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0716643 |
| RTN4 | reticulon 4 | -0.069673 |
| FLNB | filamin B, beta | -0.0695476 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0684629 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0657582 |
| RBM39 | RNA binding motif protein 39 | -0.0649195 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0634375 |
| TXNRD1 | thioredoxin reductase 1 | -0.0613149 |
| LDHA | lactate dehydrogenase A | -0.0609965 |
| ZNF292 | zinc finger protein 292 | -0.0605613 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0600799 |
| ANK2 | ankyrin 2, neuronal | -0.0587456 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0554056 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0544126 |
| NF1 | neurofibromin 1 | -0.0538361 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0529477 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.052381 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0522704 |
| NBAS | neuroblastoma amplified sequence | -0.0520894 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0517576 |
| NFIA | nuclear factor I/A | -0.0514953 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0496358 |
| NBEA | neurobeachin | -0.0485905 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0482262 |
| SMYD3 | SET and MYND domain containing 3 | -0.047812 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.046807 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0460357 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0458919 |
| TMEM41B | transmembrane protein 41B | -0.0458658 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0456086 |
| RPL35A | ribosomal protein L35a | -0.0443639 |
| COG5 | component of oligomeric golgi complex 5 | -0.0440232 |
| EVI5 | ecotropic viral integration site 5 | -0.0437789 |
| GNAS | GNAS complex locus | -0.0436246 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0435786 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0435303 |
| RPLP0 | ribosomal protein, large, P0 | -0.043528 |
| HDLBP | high density lipoprotein binding protein | -0.0425238 |
| RPL11 | ribosomal protein L11 | -0.0424918 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0421794 |
| PYGB | phosphorylase, glycogen; brain | -0.0419858 |
| EFNA5 | ephrin-A5 | -0.0417233 |
| TMSB4X | thymosin beta 4, X-linked | -0.0417102 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0413884 |
| TCF12 | transcription factor 12 | -0.0412417 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0412214 |
| PGK1 | phosphoglycerate kinase 1 | -0.0395425 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0393321 |
| USP3 | ubiquitin specific peptidase 3 | -0.0389617 |
| ACTG1 | actin gamma 1 | -0.0386584 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0385278 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0385166 |
| TMEM65 | transmembrane protein 65 | -0.0383202 |
| RPL34 | ribosomal protein L34 | -0.038163 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0374507 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0370479 |
| AHI1 | Abelson helper integration site 1 | -0.0367458 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0363979 |
| RHBDD1 | rhomboid domain containing 1 | -0.0362692 |
| SBF2 | SET binding factor 2 | -0.0362382 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0359893 |
| RPS19 | ribosomal protein S19 | -0.035828 |
| MATR3 | matrin 3 | -0.0356836 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0354884 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0353413 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0352655 |
| TMEM263 | transmembrane protein 263 | -0.0344006 |
| QKI | QKI, KH domain containing, RNA binding | -0.0341054 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0340891 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0337722 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0334671 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0334121 |
| RPL13A | ribosomal protein L13a | -0.0332147 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0329269 |
| CD47 | CD47 molecule | -0.0326757 |
| METTL15 | methyltransferase like 15 | -0.032621 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0324863 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.032372 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0321374 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0315913 |
| MSI2 | musashi RNA-binding protein 2 | -0.0315728 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.031567 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0314996 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0307698 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.03059 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0304024 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0300062 |
| GPHN | gephyrin | -0.0299055 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | -0.0298474 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0298228 |
| TMEM39A | transmembrane protein 39A | -0.0295238 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0293093 |
| S100A4 | S100 calcium binding protein A4 | -0.0291774 |
