| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anastrozole perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anastrozole_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.389001 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.142634 |
| COL6A3 | collagen, type VI, alpha 3 | 0.114422 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.105833 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0986738 |
| HDAC9 | histone deacetylase 9 | 0.0982051 |
| MSN | moesin | 0.0760748 |
| VCAN | versican | 0.0644072 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0633975 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0612386 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0569581 |
| SMAD3 | SMAD family member 3 | 0.0560637 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0549538 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0539678 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.053918 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0519766 |
| RPS2 | ribosomal protein S2 | 0.0506869 |
| THBS1 | thrombospondin 1 | 0.0506808 |
| AHNAK | AHNAK nucleoprotein | 0.0460315 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0452948 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0411657 |
| CD44 | CD44 molecule (Indian blood group) | 0.0408257 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0384056 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0376666 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0373399 |
| RPL3 | ribosomal protein L3 | 0.0365642 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0363148 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0361956 |
| ASPH | aspartate beta-hydroxylase | 0.0360021 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0357583 |
| FLNA | filamin A, alpha | 0.0353468 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0346548 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0337537 |
| VEGFA | vascular endothelial growth factor A | 0.0331548 |
| BICC1 | BicC family RNA binding protein 1 | 0.0330534 |
| SVIL | supervillin | 0.0329872 |
| CEP250 | centrosomal protein 250kDa | 0.0328317 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0322085 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0321761 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0320952 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0319231 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0318498 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0313865 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0312311 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0303615 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0297758 |
| GOLGB1 | golgin B1 | 0.0297388 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0297109 |
| TPM3 | tropomyosin 3 | 0.0291853 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0278435 |
| CUL4B | cullin 4B | 0.0277989 |
| DUSP10 | dual specificity phosphatase 10 | 0.0276185 |
| NAV2 | neuron navigator 2 | 0.0275963 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0272615 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0269617 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.026765 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0266968 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0266656 |
| RUNX1 | runt-related transcription factor 1 | 0.0265282 |
| KYNU | kynureninase | 0.0263779 |
| PKM | pyruvate kinase, muscle | 0.0263674 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0263616 |
| NONO | non-POU domain containing, octamer-binding | 0.0262974 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0258121 |
| TMSB4X | thymosin beta 4, X-linked | 0.0257853 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.02571 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0255771 |
| RND3 | Rho family GTPase 3 | 0.0247876 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0247603 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0246858 |
| APP | amyloid beta (A4) precursor protein | 0.0246158 |
| GLIS3 | GLIS family zinc finger 3 | 0.0246154 |
| SQSTM1 | sequestosome 1 | 0.0244543 |
| AHR | aryl hydrocarbon receptor | 0.0243188 |
| PLEC | plectin | 0.0242743 |
| ATXN1 | ataxin 1 | 0.0242005 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0241852 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0238325 |
| LDHA | lactate dehydrogenase A | 0.023733 |
| STC1 | stanniocalcin 1 | 0.0233225 |
| OPTN | optineurin | 0.0231063 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0229067 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0228884 |
| GPC6 | glypican 6 | 0.02236 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0223591 |
| WWOX | WW domain containing oxidoreductase | 0.0220669 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0220094 |
| ARRDC3 | arrestin domain containing 3 | 0.0219632 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0218059 |
| BRD2 | bromodomain containing 2 | 0.0216713 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0216448 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0215332 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0215051 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0214916 |
| SFTPA2 | surfactant protein A2 | 0.0214742 |
| VCL | vinculin | 0.0211622 |
| TUT7 | terminal uridylyl transferase 7 | 0.0209662 |
| RPS18 | ribosomal protein S18 | 0.0209505 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0208867 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0208342 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.286869 |
| HLA-B | major histocompatibility complex, class I, B | -0.143278 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.13829 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.127393 |
| PTMA | prothymosin, alpha | -0.10275 |
| IER3 | immediate early response 3 | -0.0993944 |
| FTL | ferritin, light polypeptide | -0.0840332 |
| TMSB10 | thymosin beta 10 | -0.0797308 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0794291 |
| RPS24 | ribosomal protein S24 | -0.0749866 |
| NDRG1 | N-myc downstream regulated 1 | -0.0708558 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.067884 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0666719 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0634072 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0631537 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0595109 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0582496 |
| CTSD | cathepsin D | -0.0562484 |
| RPL35A | ribosomal protein L35a | -0.0527547 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0526518 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0522075 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0450895 |
| RPLP2 | ribosomal protein, large, P2 | -0.0450271 |
| RPS23 | ribosomal protein S23 | -0.044479 |
| RPLP1 | ribosomal protein, large, P1 | -0.0440012 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0427145 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0413735 |
| DIAPH2 | diaphanous-related formin 2 | -0.0404207 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0398831 |
| RPL36A | ribosomal protein L36a | -0.0398356 |
| HLA-A | major histocompatibility complex, class I, A | -0.0397939 |
| GNAS | GNAS complex locus | -0.039332 |
| COL1A1 | collagen, type I, alpha 1 | -0.037346 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0364354 |
| RPS13 | ribosomal protein S13 | -0.035386 |
| CADM1 | cell adhesion molecule 1 | -0.0344431 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0339154 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0335159 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0335088 |
| HLA-E | major histocompatibility complex, class I, E | -0.0333867 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0330723 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0327673 |
| CLMP | CXADR-like membrane protein | -0.0324947 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0320441 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0317984 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.031788 |
| TPM4 | tropomyosin 4 | -0.031686 |
| RPS25 | ribosomal protein S25 | -0.031407 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0309988 |
| RPL38 | ribosomal protein L38 | -0.0307392 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0306569 |
| FBXO11 | F-box protein 11 | -0.0301878 |
| MT2A | metallothionein 2A | -0.0299336 |
| RPL27A | ribosomal protein L27a | -0.0291976 |
| RPS21 | ribosomal protein S21 | -0.028879 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0287986 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0287036 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0282009 |
| HMGA1 | high mobility group AT-hook 1 | -0.0280864 |
| RAI14 | retinoic acid induced 14 | -0.0280306 |
| QKI | QKI, KH domain containing, RNA binding | -0.0277506 |
| RPL31 | ribosomal protein L31 | -0.0275645 |
| RPL34 | ribosomal protein L34 | -0.0269996 |
| RPL7A | ribosomal protein L7a | -0.0266801 |
| RPL28 | ribosomal protein L28 | -0.0265971 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0260934 |
| RPL9 | ribosomal protein L9 | -0.0257435 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0257012 |
| S100A9 | S100 calcium binding protein A9 | -0.0255536 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0255293 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0255239 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0254058 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0253344 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0252533 |
| RPS16 | ribosomal protein S16 | -0.0251234 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0246162 |
| RPS29 | ribosomal protein S29 | -0.0242763 |
| WDR45B | WD repeat domain 45B | -0.0242506 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0241919 |
| BNC2 | basonuclin 2 | -0.0241478 |
| THOC2 | THO complex 2 | -0.0241158 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0240334 |
| LOX | lysyl oxidase | -0.0240303 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0238364 |
| PHF21A | PHD finger protein 21A | -0.0238087 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0237543 |
| RPS6 | ribosomal protein S6 | -0.0237377 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0237155 |
| FUS | FUS RNA binding protein | -0.0234034 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.023375 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0232634 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0227193 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0225964 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0225498 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0225136 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.022378 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0222606 |
| RPS8 | ribosomal protein S8 | -0.022231 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0221075 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0221008 |
