| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anastrozole perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anastrozole_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MACF1 | microtubule-actin crosslinking factor 1 | 0.163713 |
| CD44 | CD44 molecule (Indian blood group) | 0.127068 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.111971 |
| SLC38A2 | solute carrier family 38, member 2 | 0.106796 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0956354 |
| DST | dystonin | 0.0945948 |
| PKM | pyruvate kinase, muscle | 0.094444 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0932452 |
| SVIL | supervillin | 0.0900757 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0899676 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0891585 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0841046 |
| ANGPTL4 | angiopoietin-like 4 | 0.0839486 |
| RIGI | RNA sensor RIG-I | 0.0833711 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0822049 |
| AHNAK | AHNAK nucleoprotein | 0.0819771 |
| LDHA | lactate dehydrogenase A | 0.0795518 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0779596 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0760914 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0758812 |
| SMAD3 | SMAD family member 3 | 0.0707659 |
| ASPH | aspartate beta-hydroxylase | 0.0704428 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0678557 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.067504 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0659478 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0600796 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0574748 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0571063 |
| PRSS23 | protease, serine, 23 | 0.05698 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0563238 |
| TXNRD1 | thioredoxin reductase 1 | 0.0555315 |
| MSN | moesin | 0.0476199 |
| JMJD1C | jumonji domain containing 1C | 0.0475526 |
| TPI1 | triosephosphate isomerase 1 | 0.046413 |
| SQSTM1 | sequestosome 1 | 0.0455813 |
| LMO7 | LIM domain 7 | 0.0455091 |
| SET | SET nuclear proto-oncogene | 0.0454004 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0449259 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0447611 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.044658 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0439645 |
| GOLGB1 | golgin B1 | 0.0436604 |
| ANO6 | anoctamin 6 | 0.0433586 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0431817 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0419841 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0417891 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.041527 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0410914 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0410642 |
| ENO1 | enolase 1, (alpha) | 0.0407358 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0405817 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0405488 |
| PLEC | plectin | 0.0400425 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0398198 |
| ANXA1 | annexin A1 | 0.0393218 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0387572 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0381682 |
| ATXN1 | ataxin 1 | 0.0381321 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0378483 |
| ATM | ATM serine/threonine kinase | 0.0376003 |
| TPM3 | tropomyosin 3 | 0.0373575 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0372602 |
| TES | testin LIM domain protein | 0.0370201 |
| JUN | jun proto-oncogene | 0.0364977 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0363615 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0358819 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.035774 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0355548 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0353463 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0352791 |
| FMNL2 | formin-like 2 | 0.0351665 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0350903 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0350518 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0349778 |
| SDC4 | syndecan 4 | 0.0348456 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0346212 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0343511 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0340756 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0338456 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0332508 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0329217 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0326932 |
| RNF145 | ring finger protein 145 | 0.0324808 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0323958 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0322871 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0320077 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0317804 |
| EXOC4 | exocyst complex component 4 | 0.0314845 |
| PYGL | phosphorylase, glycogen, liver | 0.0314404 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0306212 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0301232 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0298974 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0298409 |
| TUT7 | terminal uridylyl transferase 7 | 0.0294504 |
| MAP1B | microtubule-associated protein 1B | 0.029134 |
| FLNB | filamin B, beta | 0.0291155 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0290284 |
| EGFR | epidermal growth factor receptor | 0.0288995 |
| SIK2 | salt-inducible kinase 2 | 0.0287625 |
| IPO7 | importin 7 | 0.0286828 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0793876 |
| GNAS | GNAS complex locus | -0.0643763 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.055902 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0552683 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0548302 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0475005 |
| RPLP1 | ribosomal protein, large, P1 | -0.0471713 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0455637 |
| HMGA2 | high mobility group AT-hook 2 | -0.0440633 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0423975 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0418525 |
| NDRG1 | N-myc downstream regulated 1 | -0.0415718 |
| SCFD1 | sec1 family domain containing 1 | -0.041199 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0391211 |
| RAB7A | RAB7A, member RAS oncogene family | -0.038905 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0377558 |
| SNX14 | sorting nexin 14 | -0.0367721 |
| EGR1 | early growth response 1 | -0.0366761 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0349593 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0349302 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0347046 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0342854 |
| VCL | vinculin | -0.0337601 |
| RPL31 | ribosomal protein L31 | -0.0335502 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0333443 |
| RPL27A | ribosomal protein L27a | -0.0313416 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0313294 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0305882 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.030127 |
| RPL35A | ribosomal protein L35a | -0.0301029 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0300553 |
| RPS23 | ribosomal protein S23 | -0.0299418 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0295968 |
| IER3 | immediate early response 3 | -0.029298 |
| DNER | delta/notch-like EGF repeat containing | -0.029255 |
| NPAT | nuclear protein, ataxia-telangiectasia locus | -0.0291486 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0290857 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0286437 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0284651 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0273576 |
| RPL15 | ribosomal protein L15 | -0.0272571 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0271328 |
| GPC6 | glypican 6 | -0.0269605 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0269394 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0267772 |
| POTEF | POTE ankyrin domain family, member F | -0.0266765 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0261656 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0260338 |
| IGF2 | insulin-like growth factor 2 | -0.0260055 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0260036 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0259853 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0259689 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0259665 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0257127 |
| ZNF721 | zinc finger protein 721 | -0.0255229 |
| FAM13B | family with sequence similarity 13, member B | -0.0254453 |
| RPS15 | ribosomal protein S15 | -0.0250183 |
| FOXO3 | forkhead box O3 | -0.02496 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.024848 |
| MED17 | mediator complex subunit 17 | -0.0248408 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0245945 |
| RPL37A | ribosomal protein L37a | -0.0245412 |
| RPL5 | ribosomal protein L5 | -0.0244199 |
| RPL37 | ribosomal protein L37 | -0.0243193 |
| RPL30 | ribosomal protein L30 | -0.0241721 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0239877 |
| SRP54 | signal recognition particle 54kDa | -0.023929 |
| TMSB10 | thymosin beta 10 | -0.0239053 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0238772 |
| RPL36 | ribosomal protein L36 | -0.0238496 |
| YAP1 | Yes-associated protein 1 | -0.0236557 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0235514 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0235445 |
| RPL36AL | ribosomal protein L36a-like | -0.0234357 |
| PCNX4 | pecanex 4 | -0.0234026 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0233636 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0233468 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0232731 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0232618 |
| RBM27 | RNA binding motif protein 27 | -0.0231911 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0230106 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.022985 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | -0.0229808 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0229543 |
| RAB6A | RAB6A, member RAS oncogene family | -0.022925 |
| LAMA5 | laminin, alpha 5 | -0.0228453 |
| NKTR | natural killer cell triggering receptor | -0.022366 |
| PTK2 | protein tyrosine kinase 2 | -0.0222315 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0221016 |
| SNX3 | sorting nexin 3 | -0.02193 |
| SAFB2 | scaffold attachment factor B2 | -0.0218412 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0218109 |
| XPO1 | exportin 1 | -0.0216976 |
| UBP1 | upstream binding protein 1 (LBP-1a) | -0.0215833 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0214284 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0214116 |
| FN1 | fibronectin 1 | -0.0213552 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0212223 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | -0.0212059 |
| FGGY | FGGY carbohydrate kinase domain containing | -0.0211983 |
