Androgen Independent Prostate Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1654637
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Genes

177 genes associated with the disease Androgen Independent Prostate Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACP3 acid phosphatase 3
AGO2 argonaute RISC catalytic component 2
AIRE autoimmune regulator
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALOX5 arachidonate 5-lipoxygenase
AQP9 aquaporin 9
AR androgen receptor
AREG amphiregulin
ARHGAP24 Rho GTPase activating protein 24
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
BCL2 B-cell CLL/lymphoma 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BRCA2 breast cancer 2, early onset
CALCA calcitonin-related polypeptide alpha
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCK cholecystokinin
CCN1 cellular communication network factor 1
CCND1 cyclin D1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFLAR CASP8 and FADD-like apoptosis regulator
CIB1 calcium and integrin binding 1 (calmyrin)
CLK2 CDC-like kinase 2
COL18A1 collagen, type XVIII, alpha 1
COX2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDR1 discoidin domain receptor tyrosine kinase 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ENO1 enolase 1, (alpha)
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
EREG epiregulin
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV1 ets variant 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2RL3 coagulation factor II (thrombin) receptor-like 3
FFAR1 free fatty acid receptor 1
FFAR4 free fatty acid receptor 4
FGF8 fibroblast growth factor 8 (androgen-induced)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
GHRH growth hormone releasing hormone
GLI2 GLI family zinc finger 2
GOLGB1 golgin B1
GPER1 G protein-coupled estrogen receptor 1
GRP gastrin-releasing peptide
GSTP1 glutathione S-transferase pi 1
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK1 homeodomain interacting protein kinase 1
HOXC8 homeobox C8
HPD 4-hydroxyphenylpyruvate dioxygenase
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI44 interferon-induced protein 44
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IL15 interleukin 15
IL17RA interleukin 17 receptor A
IL17RC interleukin 17 receptor C
IL4 interleukin 4
IL6 interleukin 6
ITK IL2-inducible T-cell kinase
IVNS1ABP influenza virus NS1A binding protein
JTB jumping translocation breakpoint
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KDR kinase insert domain receptor
KLK3 kallikrein-related peptidase 3
KMT2A lysine (K)-specific methyltransferase 2A
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LIN28B lin-28 homolog B (C. elegans)
LONP1 lon peptidase 1, mitochondrial
LOXL2 lysyl oxidase-like 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MBD2 methyl-CpG binding domain protein 2
MCL1 myeloid cell leukemia 1
MEF2C myocyte enhancer factor 2C
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MME membrane metallo-endopeptidase
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MOSPD3 motile sperm domain containing 3
MRPL58 mitochondrial ribosomal protein L58
MUC1 mucin 1, cell surface associated
NCOA4 nuclear receptor coactivator 4
NEU3 sialidase 3 (membrane sialidase)
NPEPPS aminopeptidase puromycin sensitive
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PAWR PRKC, apoptosis, WT1, regulator
PAX2 paired box 2
PBX1 pre-B-cell leukemia homeobox 1
PDZD2 PDZ domain containing 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G10 phospholipase A2, group X
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAG1 pleiomorphic adenoma gene 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PPARG peroxisome proliferator-activated receptor gamma
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRDM16 PR domain containing 16
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PROS1 protein S (alpha)
PRRT2 proline-rich transmembrane protein 2
PSAT1 phosphoserine aminotransferase 1
PTEN phosphatase and tensin homolog
PTGR1 prostaglandin reductase 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPA protein phosphatase 2 phosphatase activator
RET ret proto-oncogene
RGS2 regulator of G-protein signaling 2
RIOX1 ribosomal oxygenase 1
RUNX2 runt-related transcription factor 2
SFRP4 secreted frizzled-related protein 4
SGSM3 small G protein signaling modulator 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC12A9 solute carrier family 12, member 9
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SOX2 SRY (sex determining region Y)-box 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STEAP4 STEAP family member 4
SUB1 SUB1 homolog (S. cerevisiae)
TFPI2 tissue factor pathway inhibitor 2
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNK2 tyrosine kinase, non-receptor, 2
TP53 tumor protein p53
TP73 tumor protein p73
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TWIST1 twist family bHLH transcription factor 1
USF2 upstream transcription factor 2, c-fos interacting
VCP valosin containing protein
VIM vimentin
VIP vasoactive intestinal peptide
VSX1 visual system homeobox 1
WDR77 WD repeat domain 77
WISP3 WNT1 inducible signaling pathway protein 3
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YAP1 Yes-associated protein 1