Anemia Gene Set

Dataset DISEASES Curated Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A reduction in the number of circulating erythrocytes or in the quantity of hemoglobin. (Experimental Factor Ontology, EFO_0004272)
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Genes

94 genes involed in the disease Anemia from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.

Symbol Name Standardized Value
AMN amnion associated transmembrane protein 5.0
RPS15 ribosomal protein S15 5.0
ALAS2 5'-aminolevulinate synthase 2 5.0
RPL31 ribosomal protein L31 5.0
FANCM Fanconi anemia, complementation group M 5.0
RPS27A ribosomal protein S27a 5.0
ATRX alpha thalassemia/mental retardation syndrome X-linked 5.0
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 5.0
HFE hemochromatosis 5.0
CUBN cubilin (intrinsic factor-cobalamin receptor) 5.0
RPL36 ribosomal protein L36 5.0
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 5.0
RPS15A ribosomal protein S15a 4.0
PALB2 partner and localizer of BRCA2 4.0
ATP11C ATPase, class VI, type 11C 4.0
HEATR3 HEAT repeat containing 3 4.0
ADA adenosine deaminase 4.0
BPGM 2,3-bisphosphoglycerate mutase 4.0
SEC23B Sec23 homolog B (S. cerevisiae) 4.0
EPB41 erythrocyte membrane protein band 4.1 4.0
G6PD glucose-6-phosphate dehydrogenase 4.0
RPL35 ribosomal protein L35 4.0
GPI glucose-6-phosphate isomerase 4.0
UBE2T ubiquitin-conjugating enzyme E2T 4.0
FANCD2 Fanconi anemia, complementation group D2 4.0
HBA1 hemoglobin, alpha 1 4.0
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 4.0
EPB42 erythrocyte membrane protein band 4.2 4.0
RACGAP1 Rac GTPase activating protein 1 4.0
GCLC glutamate-cysteine ligase, catalytic subunit 4.0
GSS glutathione synthetase 4.0
GSR glutathione reductase 4.0
GATA1 GATA binding protein 1 (globin transcription factor 1) 4.0
RPS7 ribosomal protein S7 4.0
RPL27 ribosomal protein L27 4.0
RPL26 ribosomal protein L26 4.0
ACSL4 acyl-CoA synthetase long-chain family member 4 4.0
LPIN2 lipin 2 4.0
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 4.0
RFWD3 ring finger and WD repeat domain 3 4.0
FANCF Fanconi anemia, complementation group F 4.0
HBA2 hemoglobin, alpha 2 4.0
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 4.0
SLX4 SLX4 structure-specific endonuclease subunit 4.0
RPS10 ribosomal protein S10 4.0
RPS17 ribosomal protein S17 4.0
RPS19 ribosomal protein S19 4.0
RPL15 ribosomal protein L15 4.0
RPL11 ribosomal protein L11 4.0
RPL18 ribosomal protein L18 4.0
ALDOA aldolase A, fructose-bisphosphate 4.0
BRIP1 BRCA1 interacting protein C-terminal helicase 1 4.0
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 4.0
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 4.0
HK1 hexokinase 1 4.0
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 4.0
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 4.0
RPS26 ribosomal protein S26 4.0
RPS27 ribosomal protein S27 4.0
RPS24 ribosomal protein S24 4.0
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 4.0
TPI1 triosephosphate isomerase 1 4.0
FANCI Fanconi anemia, complementation group I 4.0
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 4.0
SPTA1 spectrin, alpha, erythrocytic 1 4.0
FANCG Fanconi anemia, complementation group G 4.0
FANCE Fanconi anemia, complementation group E 4.0
FANCC Fanconi anemia, complementation group C 4.0
FANCB Fanconi anemia, complementation group B 4.0
FANCA Fanconi anemia, complementation group A 4.0
FANCL Fanconi anemia, complementation group L 4.0
RPS28 ribosomal protein S28 4.0
RPS29 ribosomal protein S29 4.0
ERCC4 excision repair cross-complementation group 4 4.0
CPOX coproporphyrinogen oxidase 4.0
PIEZO1 piezo-type mechanosensitive ion channel component 1 4.0
ANK1 ankyrin 1, erythrocytic 4.0
RAD51 RAD51 recombinase 4.0
SPTB spectrin, beta, erythrocytic 4.0
HBB hemoglobin, beta 4.0
BRCA1 breast cancer 1, early onset 4.0
BRCA2 breast cancer 2, early onset 4.0
CDAN1 codanin 1 4.0
RPL35A ribosomal protein L35a 4.0
SLC19A1 solute carrier family 19 (folate transporter), member 1 4.0
PGK1 phosphoglycerate kinase 1 4.0
CD59 CD59 molecule, complement regulatory protein 4.0
RPL5 ribosomal protein L5 4.0
KLF1 Kruppel-like factor 1 (erythroid) 4.0
RAD51C RAD51 paralog C 4.0
PKLR pyruvate kinase, liver and RBC 4.0
AK1 adenylate kinase 1 4.0
RHAG Rh-associated glycoprotein 4.0
KIF23 kinesin family member 23 4.0