| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.172884 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.171042 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.157522 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.123631 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.120078 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.100478 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0958818 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0920024 |
| PLEC | plectin | 0.0765557 |
| LMNA | lamin A/C | 0.0742184 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0741785 |
| MT2A | metallothionein 2A | 0.072519 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0695928 |
| HDAC9 | histone deacetylase 9 | 0.0691362 |
| APP | amyloid beta (A4) precursor protein | 0.0681887 |
| CALR | calreticulin | 0.0678757 |
| AHNAK | AHNAK nucleoprotein | 0.0657113 |
| DST | dystonin | 0.059826 |
| PTMA | prothymosin, alpha | 0.0590822 |
| PLAT | plasminogen activator, tissue | 0.0579437 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0560371 |
| SQSTM1 | sequestosome 1 | 0.0553472 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0550862 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0526628 |
| CD44 | CD44 molecule (Indian blood group) | 0.0519524 |
| SEPTIN9 | septin 9 | 0.051406 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0506361 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0496627 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0491545 |
| TMSB4X | thymosin beta 4, X-linked | 0.0485369 |
| SFTPA2 | surfactant protein A2 | 0.0478858 |
| NAV2 | neuron navigator 2 | 0.0473291 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0472476 |
| TLE4 | transducin-like enhancer of split 4 | 0.0461769 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0445411 |
| OGA | O-GlcNAcase | 0.0440796 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0437724 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0428148 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0423945 |
| COL3A1 | collagen, type III, alpha 1 | 0.0423602 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0419911 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0419684 |
| HLA-B | major histocompatibility complex, class I, B | 0.0415455 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0410735 |
| LOXL2 | lysyl oxidase-like 2 | 0.0407162 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0405376 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0401359 |
| RRBP1 | ribosome binding protein 1 | 0.0397324 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0394139 |
| HDLBP | high density lipoprotein binding protein | 0.0388915 |
| FSTL1 | follistatin-like 1 | 0.0386472 |
| FLNA | filamin A, alpha | 0.0382091 |
| CAVIN1 | caveolae associated protein 1 | 0.0381928 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0375644 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.037225 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0362757 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0361779 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0361707 |
| PRSS23 | protease, serine, 23 | 0.0356301 |
| MSN | moesin | 0.0346945 |
| PRELID2 | PRELI domain containing 2 | 0.0343352 |
| VCL | vinculin | 0.0340669 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0336176 |
| JMJD1C | jumonji domain containing 1C | 0.0326657 |
| CANX | calnexin | 0.0318133 |
| MT1X | metallothionein 1X | 0.0314949 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0310337 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0308121 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0300213 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0299376 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0296787 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0293354 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0288776 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0285607 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0284135 |
| FMNL2 | formin-like 2 | 0.0283178 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0277864 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0275459 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0272698 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0269625 |
| FNIP1 | folliculin interacting protein 1 | 0.0269422 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0266946 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0265911 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0262213 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0261216 |
| RASAL2 | RAS protein activator like 2 | 0.0258701 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0256739 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0256234 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0255661 |
| MB21D2 | Mab-21 domain containing 2 | 0.0255154 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0254958 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0252898 |
| ACTN1 | actinin, alpha 1 | 0.0252784 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0252308 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0249565 |
| GLIS3 | GLIS family zinc finger 3 | 0.0247828 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0243625 |
| FBN1 | fibrillin 1 | 0.0243161 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0242838 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0242651 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.336447 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.203314 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0849902 |
| FN1 | fibronectin 1 | -0.0825869 |
| POTEF | POTE ankyrin domain family, member F | -0.0824203 |
| PODXL | podocalyxin-like | -0.0821611 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0778948 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0772394 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0650558 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0573425 |
| SUCNR1 | succinate receptor 1 | -0.056947 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0568571 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0551372 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0475809 |
| DCLK2 | doublecortin-like kinase 2 | -0.0468728 |
| MYADM | myeloid-associated differentiation marker | -0.0458747 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.044815 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0432512 |
| COL5A1 | collagen, type V, alpha 1 | -0.0411847 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0401489 |
| NAV1 | neuron navigator 1 | -0.0395996 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0386792 |
| RUNX1 | runt-related transcription factor 1 | -0.038328 |
| FOSL1 | FOS-like antigen 1 | -0.037044 |
| TPM4 | tropomyosin 4 | -0.0365951 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0347952 |
| CDH13 | cadherin 13 | -0.034784 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.033867 |
| TPM1 | tropomyosin 1 (alpha) | -0.0336792 |
| EGFR | epidermal growth factor receptor | -0.0307113 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0305647 |
| PKM | pyruvate kinase, muscle | -0.0291408 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0290289 |
| LOX | lysyl oxidase | -0.0283884 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0283598 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0280246 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0273483 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0271763 |
| TAGLN2 | transgelin 2 | -0.0268588 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0268422 |
| ANXA2 | annexin A2 | -0.0267218 |
| PLXNA2 | plexin A2 | -0.0264876 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0262341 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0253336 |
| THBS2 | thrombospondin 2 | -0.0244436 |
| MSI2 | musashi RNA-binding protein 2 | -0.0241267 |
| SP3 | Sp3 transcription factor | -0.0240293 |
| CCND1 | cyclin D1 | -0.0238861 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0237304 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0233761 |
| DEPP1 | DEPP autophagy regulator 1 | -0.022802 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0227831 |
| MAP1B | microtubule-associated protein 1B | -0.0227001 |
| LRRC17 | leucine rich repeat containing 17 | -0.0221881 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0215387 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.021005 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0209614 |
| CENPF | centromere protein F, 350/400kDa | -0.0202065 |
| MYOF | myoferlin | -0.0199376 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0196141 |
| L1CAM | L1 cell adhesion molecule | -0.0191939 |
| TNS3 | tensin 3 | -0.0191497 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0185714 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0179745 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0177047 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0165072 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0161035 |
| KRT81 | keratin 81, type II | -0.0157526 |
| TAPBP | TAP binding protein (tapasin) | -0.0154554 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0152279 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0150971 |
| PXDN | peroxidasin | -0.0145765 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0145493 |
| INSIG2 | insulin induced gene 2 | -0.0145079 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.014461 |
| LAMA5 | laminin, alpha 5 | -0.0142383 |
| PFN1 | profilin 1 | -0.0141208 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0139812 |
| LDHA | lactate dehydrogenase A | -0.0139201 |
| LNPK | lunapark, ER junction formation factor | -0.0139195 |
| SYTL3 | synaptotagmin-like 3 | -0.013285 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.013239 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0131615 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0130738 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0130053 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0129615 |
| TOX | thymocyte selection-associated high mobility group box | -0.012879 |
| CCN2 | cellular communication network factor 2 | -0.012871 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | -0.0126435 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0125155 |
| TSPAN9 | tetraspanin 9 | -0.0123877 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0122349 |
| NOTCH2 | notch 2 | -0.0122085 |
| DSTN | destrin (actin depolymerizing factor) | -0.0121667 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.01175 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0114928 |
| ZNF292 | zinc finger protein 292 | -0.011362 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0112527 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0111837 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0111454 |
