| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.185256 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.140587 |
| JMJD1C | jumonji domain containing 1C | 0.109939 |
| RAB7A | RAB7A, member RAS oncogene family | 0.105433 |
| ADIPOR2 | adiponectin receptor 2 | 0.0884464 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0868438 |
| VIM | vimentin | 0.0864782 |
| HMGA2 | high mobility group AT-hook 2 | 0.08405 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0803186 |
| RRM2 | ribonucleotide reductase M2 | 0.0776179 |
| INTS6 | integrator complex subunit 6 | 0.0725184 |
| TMSB10 | thymosin beta 10 | 0.0697337 |
| YAP1 | Yes-associated protein 1 | 0.0694192 |
| TPI1 | triosephosphate isomerase 1 | 0.0691159 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0686395 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.06845 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0621646 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0617531 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0600721 |
| YBX3 | Y box binding protein 3 | 0.0567323 |
| ACTG1 | actin gamma 1 | 0.0562628 |
| RPS27A | ribosomal protein S27a | 0.0547463 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.054538 |
| DENND5A | DENN/MADD domain containing 5A | 0.0539342 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0522193 |
| RPS12 | ribosomal protein S12 | 0.0520489 |
| PTMA | prothymosin, alpha | 0.0517171 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0484691 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0484327 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0477776 |
| SPAG9 | sperm associated antigen 9 | 0.0464322 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0463907 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0450416 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.043981 |
| RCOR1 | REST corepressor 1 | 0.0429243 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0428254 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0427405 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0427301 |
| ASPH | aspartate beta-hydroxylase | 0.0427098 |
| UBC | ubiquitin C | 0.0411996 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0396183 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0393543 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0389674 |
| RPL3 | ribosomal protein L3 | 0.0385291 |
| CALR | calreticulin | 0.0385014 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0382039 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0372507 |
| CLTC | clathrin, heavy chain (Hc) | 0.0371527 |
| TPM3 | tropomyosin 3 | 0.0370052 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.035955 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0357693 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0357656 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0357278 |
| BRD2 | bromodomain containing 2 | 0.0355377 |
| NF1 | neurofibromin 1 | 0.0354686 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0353419 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0351417 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0348324 |
| LRRC23 | leucine rich repeat containing 23 | 0.0343152 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0342186 |
| GSK3B | glycogen synthase kinase 3 beta | 0.033876 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0338749 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0336965 |
| SETX | senataxin | 0.0336378 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0333399 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0331346 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0330182 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0328887 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0327238 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0327018 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0326983 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0325511 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0320262 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0319824 |
| RPS8 | ribosomal protein S8 | 0.0319699 |
| MTAP | methylthioadenosine phosphorylase | 0.03169 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0316119 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0315087 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0312649 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0311545 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0310897 |
| SIK3 | SIK family kinase 3 | 0.0310748 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0309216 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0303571 |
| CREBBP | CREB binding protein | 0.0301815 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0301418 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0301193 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0298193 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0298059 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0295694 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0294318 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0293892 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0292032 |
| RAB10 | RAB10, member RAS oncogene family | 0.0291114 |
| H3-3B | H3.3 histone B | 0.0290947 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0290904 |
| JUN | jun proto-oncogene | 0.0290856 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0290776 |
| EDARADD | EDAR-associated death domain | 0.0285704 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0285094 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.15629 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.138708 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0943154 |
| MMP12 | matrix metallopeptidase 12 | -0.056202 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0551611 |
| SYT1 | synaptotagmin I | -0.053171 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0488884 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.048764 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0382913 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0379874 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0354775 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0351305 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0350792 |
| BCHE | butyrylcholinesterase | -0.0344072 |
| TMEM123 | transmembrane protein 123 | -0.0338319 |
| RPL35A | ribosomal protein L35a | -0.0328797 |
| EDN1 | endothelin 1 | -0.0323428 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0317801 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0311722 |
| OXR1 | oxidation resistance 1 | -0.0303494 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0295765 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0286991 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0285727 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0279722 |
| CCN2 | cellular communication network factor 2 | -0.0279247 |
| YEATS2 | YEATS domain containing 2 | -0.0278302 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0278064 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0268222 |
| POTEF | POTE ankyrin domain family, member F | -0.026624 |
| ZNF292 | zinc finger protein 292 | -0.0263131 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0260038 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0257857 |
| TSPAN5 | tetraspanin 5 | -0.0256718 |
| EPHA6 | EPH receptor A6 | -0.024874 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0238919 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.023684 |
| HMGA1 | high mobility group AT-hook 1 | -0.0236469 |
| TXNRD1 | thioredoxin reductase 1 | -0.0219536 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0216253 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0215328 |
| CDK6 | cyclin-dependent kinase 6 | -0.0212998 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0206418 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0205171 |
| NHSL1 | NHS-like 1 | -0.0204577 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0203987 |
| CLDN1 | claudin 1 | -0.0203385 |
| MAP1B | microtubule-associated protein 1B | -0.0203207 |
| NRG1 | neuregulin 1 | -0.0202029 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0200426 |
| XPO1 | exportin 1 | -0.0199329 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0196859 |
| WDR45B | WD repeat domain 45B | -0.0195539 |
| LDHB | lactate dehydrogenase B | -0.0190929 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0185401 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0184001 |
| TPD52 | tumor protein D52 | -0.0182449 |
| RPL36 | ribosomal protein L36 | -0.0181714 |
| VRK2 | vaccinia related kinase 2 | -0.0181485 |
| GASK1B | golgi associated kinase 1B | -0.0179771 |
| PGK1 | phosphoglycerate kinase 1 | -0.0178423 |
| NEK7 | NIMA-related kinase 7 | -0.0177222 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.0176764 |
| SEPTIN7 | septin 7 | -0.0176748 |
| AHNAK | AHNAK nucleoprotein | -0.0174845 |
| DTNA | dystrobrevin, alpha | -0.0173535 |
| EGFR | epidermal growth factor receptor | -0.0172984 |
| FAM117B | family with sequence similarity 117, member B | -0.0172798 |
| ZFP64 | ZFP64 zinc finger protein | -0.0171974 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0171912 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0171337 |
| RPL32 | ribosomal protein L32 | -0.0170969 |
| NEBL | nebulette | -0.0170472 |
| NKTR | natural killer cell triggering receptor | -0.0170129 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0169751 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0167367 |
| RPS26 | ribosomal protein S26 | -0.0167285 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0166335 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0165809 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0165498 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0164477 |
| THUMPD2 | THUMP domain containing 2 | -0.0163562 |
| CCDC14 | coiled-coil domain containing 14 | -0.0163182 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0163136 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0163131 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.016182 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0160602 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0159885 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0156751 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0156738 |
| FSTL5 | follistatin-like 5 | -0.0156238 |
| BBX | bobby sox homolog (Drosophila) | -0.0155772 |
| CDCA2 | cell division cycle associated 2 | -0.0155105 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0155007 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0154868 |
| WWC1 | WW and C2 domain containing 1 | -0.0154673 |
| MPG | N-methylpurine-DNA glycosylase | -0.0152682 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0152513 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0152478 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0150342 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0149814 |
