| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.210814 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.154084 |
| EXT1 | exostosin glycosyltransferase 1 | 0.128225 |
| PLEC | plectin | 0.10313 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0872987 |
| TMSB10 | thymosin beta 10 | 0.0867842 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0815763 |
| CTBP2 | C-terminal binding protein 2 | 0.0802877 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0772301 |
| NAV2 | neuron navigator 2 | 0.067969 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.065505 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0618642 |
| AHNAK | AHNAK nucleoprotein | 0.0596331 |
| RNF213 | ring finger protein 213 | 0.059348 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0578613 |
| FUS | FUS RNA binding protein | 0.0574171 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0560486 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0523525 |
| APOL1 | apolipoprotein L, 1 | 0.0519771 |
| SFTPA2 | surfactant protein A2 | 0.0518262 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.050369 |
| SEPTIN9 | septin 9 | 0.0485708 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0485021 |
| NDRG1 | N-myc downstream regulated 1 | 0.0484913 |
| FMNL2 | formin-like 2 | 0.0475867 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.047425 |
| LMNA | lamin A/C | 0.0463221 |
| APP | amyloid beta (A4) precursor protein | 0.0449481 |
| TLE4 | transducin-like enhancer of split 4 | 0.0446565 |
| HLA-B | major histocompatibility complex, class I, B | 0.0441442 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0437018 |
| CALR | calreticulin | 0.0435486 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0422433 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0418777 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0414991 |
| KYNU | kynureninase | 0.0409223 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0404932 |
| INTS6 | integrator complex subunit 6 | 0.0399607 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0388501 |
| SMAD3 | SMAD family member 3 | 0.0386653 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.037694 |
| ANKRD11 | ankyrin repeat domain 11 | 0.037666 |
| RRBP1 | ribosome binding protein 1 | 0.0375747 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0364712 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0358944 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0353153 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0350915 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0343064 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0337393 |
| PRKCA | protein kinase C, alpha | 0.033524 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0326873 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0320281 |
| LOXL2 | lysyl oxidase-like 2 | 0.0318593 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0317998 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0316853 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0314937 |
| RPL19 | ribosomal protein L19 | 0.0310322 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.030342 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0302645 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0301343 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.030108 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0296339 |
| JAK1 | Janus kinase 1 | 0.0289996 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0288803 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0287347 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0284137 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0280733 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0279123 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0278404 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.027456 |
| MSN | moesin | 0.0274267 |
| B2M | beta-2-microglobulin | 0.02737 |
| SQSTM1 | sequestosome 1 | 0.0271975 |
| FTL | ferritin, light polypeptide | 0.026703 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0266454 |
| RPL3 | ribosomal protein L3 | 0.0264959 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0261577 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.026152 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0261229 |
| RPLP2 | ribosomal protein, large, P2 | 0.0261039 |
| RPS4X | ribosomal protein S4, X-linked | 0.0257842 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0257173 |
| SP100 | SP100 nuclear antigen | 0.0255974 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0254317 |
| UBC | ubiquitin C | 0.0253128 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0253052 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0252891 |
| MCL1 | myeloid cell leukemia 1 | 0.0252095 |
| VCP | valosin containing protein | 0.0251507 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0251465 |
| TPM3 | tropomyosin 3 | 0.0248754 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0247498 |
| MT2A | metallothionein 2A | 0.0247455 |
| RPS21 | ribosomal protein S21 | 0.0247181 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0246854 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0246606 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0239483 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0239337 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0238104 |
| TOP1 | topoisomerase (DNA) I | 0.0237853 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.2995 |
| FRMD4A | FERM domain containing 4A | -0.203049 |
| GPC6 | glypican 6 | -0.145376 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.125821 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.11351 |
| POTEF | POTE ankyrin domain family, member F | -0.108201 |
| RAI14 | retinoic acid induced 14 | -0.0989894 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0972235 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0877725 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0793233 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0713088 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.065113 |
| RTN4 | reticulon 4 | -0.057964 |
| NRP2 | neuropilin 2 | -0.0543199 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0516572 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0493108 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0477485 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0415335 |
| PLK2 | polo-like kinase 2 | -0.0409742 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0379425 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0363241 |
| TGFB2 | transforming growth factor, beta 2 | -0.0348971 |
| MYADM | myeloid-associated differentiation marker | -0.0347885 |
| TNS3 | tensin 3 | -0.0342119 |
| FN1 | fibronectin 1 | -0.033966 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0338764 |
| TPM4 | tropomyosin 4 | -0.0327574 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0327379 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0312705 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0310401 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0304078 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0294367 |
| GDF15 | growth differentiation factor 15 | -0.02912 |
| RND3 | Rho family GTPase 3 | -0.0287606 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0279136 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0274344 |
| LIMA1 | LIM domain and actin binding 1 | -0.0271541 |
| NRP1 | neuropilin 1 | -0.0270333 |
| MAP1B | microtubule-associated protein 1B | -0.0269554 |
| CP | ceruloplasmin (ferroxidase) | -0.0266008 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0265695 |
| GLIS3 | GLIS family zinc finger 3 | -0.0260093 |
| PTH2R | parathyroid hormone 2 receptor | -0.0248113 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0246118 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.024465 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0242242 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0239654 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0232716 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0228984 |
| ATXN10 | ataxin 10 | -0.0225906 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0222897 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0221536 |
| ETV6 | ets variant 6 | -0.022082 |
| WDR43 | WD repeat domain 43 | -0.0211747 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0210498 |
| EHBP1 | EH domain binding protein 1 | -0.021006 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0208402 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0207611 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0205001 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.0203369 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0203218 |
| PFN1 | profilin 1 | -0.0199356 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.01964 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0196152 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0194882 |
| TGM2 | transglutaminase 2 | -0.0192497 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0192246 |
| PALLD | palladin, cytoskeletal associated protein | -0.019063 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0190265 |
| SCFD2 | sec1 family domain containing 2 | -0.01894 |
| NUCB2 | nucleobindin 2 | -0.0187559 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | -0.0187123 |
| OXR1 | oxidation resistance 1 | -0.0186425 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0186006 |
| EGR1 | early growth response 1 | -0.0185619 |
| GOLGA4 | golgin A4 | -0.0185351 |
| STOM | stomatin | -0.0184487 |
| UBXN4 | UBX domain protein 4 | -0.0184361 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0184343 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0182675 |
| DIAPH2 | diaphanous-related formin 2 | -0.0181982 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0181488 |
| PLS3 | plastin 3 | -0.0179881 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 | -0.0179795 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0179129 |
| VIRMA | vir like m6A methyltransferase associated | -0.0178206 |
| PLIN2 | perilipin 2 | -0.0178097 |
| SRP54 | signal recognition particle 54kDa | -0.0177707 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0177543 |
| TSPAN13 | tetraspanin 13 | -0.0175767 |
| FNBP4 | formin binding protein 4 | -0.0174155 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0173408 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0173386 |
| NOTCH2 | notch 2 | -0.0173357 |
| TPM1 | tropomyosin 1 (alpha) | -0.0173214 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0172567 |
| TMEM41B | transmembrane protein 41B | -0.0172497 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0171901 |
| HMGA1 | high mobility group AT-hook 1 | -0.0171465 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0171272 |
