| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KYNU | kynureninase | 0.125981 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.12477 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.117332 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0997925 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0947588 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0947249 |
| VCL | vinculin | 0.0904596 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0867582 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0851677 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0826416 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0821721 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0783118 |
| TMSB10 | thymosin beta 10 | 0.0777698 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0726866 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0711599 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0703675 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0672183 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0668711 |
| USP47 | ubiquitin specific peptidase 47 | 0.066465 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0655139 |
| ACTG1 | actin gamma 1 | 0.0641488 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0639476 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0637108 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0633404 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0612174 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.061072 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0604977 |
| MT1X | metallothionein 1X | 0.0585911 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0574317 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0567623 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0539523 |
| PLEC | plectin | 0.0527326 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0523552 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0508803 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.049718 |
| SP100 | SP100 nuclear antigen | 0.0480532 |
| BMP6 | bone morphogenetic protein 6 | 0.0474226 |
| MYO10 | myosin X | 0.0441283 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0436537 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0436368 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0427853 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.042774 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0424458 |
| STC1 | stanniocalcin 1 | 0.0416248 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0411898 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0407912 |
| FRMD6 | FERM domain containing 6 | 0.0407145 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0404249 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0403458 |
| FLNA | filamin A, alpha | 0.0399067 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0391361 |
| MT2A | metallothionein 2A | 0.0390281 |
| LMO7 | LIM domain 7 | 0.0390239 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.038808 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0384883 |
| WWC1 | WW and C2 domain containing 1 | 0.0382831 |
| EGFR | epidermal growth factor receptor | 0.0380905 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.037993 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0376327 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0375238 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0371072 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0363603 |
| OSMR | oncostatin M receptor | 0.0362727 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0360953 |
| BCL2L1 | BCL2-like 1 | 0.0360094 |
| AADAC | arylacetamide deacetylase | 0.0357673 |
| INTS6 | integrator complex subunit 6 | 0.0350133 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0347919 |
| LAMC2 | laminin, gamma 2 | 0.0347132 |
| ASPH | aspartate beta-hydroxylase | 0.0342527 |
| CTBP2 | C-terminal binding protein 2 | 0.0342149 |
| RSPO3 | R-spondin 3 | 0.0333422 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0332748 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0329947 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0325242 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0324464 |
| NABP1 | nucleic acid binding protein 1 | 0.0322943 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0316526 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0305532 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0301235 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0298731 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0297843 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0293643 |
| RPL23 | ribosomal protein L23 | 0.0291249 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0291228 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0280765 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0280646 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0275513 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0274024 |
| ETNK1 | ethanolamine kinase 1 | 0.027388 |
| CD44 | CD44 molecule (Indian blood group) | 0.027295 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.027157 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0270059 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0267151 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0266329 |
| WWOX | WW domain containing oxidoreductase | 0.0264062 |
| FAT1 | FAT atypical cadherin 1 | 0.0263324 |
| MSN | moesin | 0.0262237 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0262215 |
| KLF6 | Kruppel-like factor 6 | 0.0261435 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.195109 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.179165 |
| NDRG1 | N-myc downstream regulated 1 | -0.147848 |
| CA12 | carbonic anhydrase XII | -0.12312 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0929588 |
| ANXA4 | annexin A4 | -0.0590023 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0580157 |
| RIN2 | Ras and Rab interactor 2 | -0.057698 |
| FAM13A | family with sequence similarity 13, member A | -0.0554553 |
| RAI14 | retinoic acid induced 14 | -0.0528383 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0520975 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0500869 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0495597 |
| FLNB | filamin B, beta | -0.0494997 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0485595 |
| USP3 | ubiquitin specific peptidase 3 | -0.0462929 |
| FA2H | fatty acid 2-hydroxylase | -0.0462474 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0462448 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0431899 |
| GOLGA4 | golgin A4 | -0.0430131 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0426018 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0422193 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0405977 |
| PGK1 | phosphoglycerate kinase 1 | -0.0404134 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0402692 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.040097 |
| RNF213 | ring finger protein 213 | -0.0395175 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0394955 |
| HIP1 | huntingtin interacting protein 1 | -0.0394722 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0380765 |
| SBF2 | SET binding factor 2 | -0.0378775 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0368908 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0358525 |
| AOPEP | aminopeptidase O (putative) | -0.0356501 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0330711 |
| COL5A2 | collagen, type V, alpha 2 | -0.0328976 |
| ZNF292 | zinc finger protein 292 | -0.0323827 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0318513 |
| PTMA | prothymosin, alpha | -0.031793 |
| EHBP1 | EH domain binding protein 1 | -0.030944 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0303711 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0303117 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0301425 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0301377 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0291284 |
| PYGL | phosphorylase, glycogen, liver | -0.0288869 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.02854 |
| TNS3 | tensin 3 | -0.028173 |
| ANGPTL4 | angiopoietin-like 4 | -0.0278659 |
| ADM | adrenomedullin | -0.0276038 |
| FTL | ferritin, light polypeptide | -0.0273495 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0268983 |
| HELZ | helicase with zinc finger | -0.0268692 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0267681 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0267422 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0263607 |
| DAPK1 | death-associated protein kinase 1 | -0.026344 |
| SRP54 | signal recognition particle 54kDa | -0.0262155 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0260868 |
| SEC24A | SEC24 family member A | -0.0260373 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0260124 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0259039 |
| FNBP4 | formin binding protein 4 | -0.0255584 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0252113 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0244963 |
| TCIM | transcriptional and immune response regulator | -0.024423 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0244211 |
| NGLY1 | N-glycanase 1 | -0.0244127 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0239594 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0238472 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0234602 |
| PFKP | phosphofructokinase, platelet | -0.0232509 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0230369 |
| WDR45B | WD repeat domain 45B | -0.0229877 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0229843 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0228138 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0225102 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0224081 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0223689 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | -0.0222286 |
| DENND4C | DENN/MADD domain containing 4C | -0.0222076 |
| MYO1E | myosin IE | -0.0222038 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0221087 |
| RGS17 | regulator of G-protein signaling 17 | -0.0220084 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0219761 |
| RNF24 | ring finger protein 24 | -0.0218453 |
| CD109 | CD109 molecule | -0.0218084 |
| CD99 | CD99 molecule | -0.0217733 |
| TGM2 | transglutaminase 2 | -0.0216534 |
| LAMA5 | laminin, alpha 5 | -0.0216149 |
| ANO6 | anoctamin 6 | -0.0216047 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0216015 |
| CDCP1 | CUB domain containing protein 1 | -0.0215763 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0212393 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0212034 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.021044 |
| LDHA | lactate dehydrogenase A | -0.021036 |
| KIF16B | kinesin family member 16B | -0.0208935 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0208567 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0205511 |
