| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.146929 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.109921 |
| PLEC | plectin | 0.0923702 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0883829 |
| LAMC2 | laminin, gamma 2 | 0.0840977 |
| LAMA4 | laminin, alpha 4 | 0.0792936 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0783246 |
| EZR | ezrin | 0.0701992 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0672911 |
| ACTN4 | actinin, alpha 4 | 0.0647884 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0643653 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0631934 |
| VCL | vinculin | 0.0629881 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0619656 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0618467 |
| RASAL2 | RAS protein activator like 2 | 0.0614176 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0608626 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0601018 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0597765 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0587568 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0584666 |
| DSPP | dentin sialophosphoprotein | 0.0582221 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0557493 |
| SLC38A2 | solute carrier family 38, member 2 | 0.054343 |
| MYOF | myoferlin | 0.0524155 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0483451 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0480904 |
| CORO1C | coronin, actin binding protein, 1C | 0.0477398 |
| EGFR | epidermal growth factor receptor | 0.0472204 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0470068 |
| INTS6 | integrator complex subunit 6 | 0.0456953 |
| HDAC9 | histone deacetylase 9 | 0.0454198 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0446522 |
| CAB39 | calcium binding protein 39 | 0.0445058 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0440426 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0436971 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0435426 |
| BCL2L1 | BCL2-like 1 | 0.0433259 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0430787 |
| RCOR1 | REST corepressor 1 | 0.0426918 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0424519 |
| ERBIN | erbb2 interacting protein | 0.0418031 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0417599 |
| NDRG1 | N-myc downstream regulated 1 | 0.0415189 |
| HMGA2 | high mobility group AT-hook 2 | 0.0414371 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0414325 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0406381 |
| SEPTIN9 | septin 9 | 0.0403073 |
| MSN | moesin | 0.0396205 |
| SMAD3 | SMAD family member 3 | 0.0395463 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0395159 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0393479 |
| AHNAK | AHNAK nucleoprotein | 0.0393082 |
| ANXA11 | annexin A11 | 0.0387061 |
| ITGA6 | integrin, alpha 6 | 0.038381 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0381561 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0379421 |
| FBXO11 | F-box protein 11 | 0.0379071 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0354826 |
| EFNA5 | ephrin-A5 | 0.0353385 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0353348 |
| TJP1 | tight junction protein 1 | 0.03456 |
| TMEM164 | transmembrane protein 164 | 0.0344313 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.034357 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0341639 |
| MED13L | mediator complex subunit 13-like | 0.0340059 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0332629 |
| WWC1 | WW and C2 domain containing 1 | 0.0326142 |
| TGFA | transforming growth factor, alpha | 0.0326072 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0325219 |
| TGM2 | transglutaminase 2 | 0.0319648 |
| GSK3B | glycogen synthase kinase 3 beta | 0.030977 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0307082 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0306435 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0304904 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0297015 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0293066 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0288462 |
| SGMS2 | sphingomyelin synthase 2 | 0.0285864 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0278077 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0275142 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0273671 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0271302 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.026564 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0265099 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0264521 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0262862 |
| KRT8 | keratin 8, type II | 0.0258841 |
| NABP1 | nucleic acid binding protein 1 | 0.0257977 |
| DIAPH1 | diaphanous-related formin 1 | 0.0257459 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0254311 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0252875 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0252237 |
| HOMER1 | homer scaffolding protein 1 | 0.0251483 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0249939 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0248388 |
| CREBBP | CREB binding protein | 0.0247838 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0247482 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0246204 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0245974 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.147985 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.137793 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.129853 |
| TXNRD1 | thioredoxin reductase 1 | -0.126132 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.120167 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.11989 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.112785 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0876703 |
| LAMB3 | laminin, beta 3 | -0.0859645 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0852173 |
| B2M | beta-2-microglobulin | -0.0713771 |
| FTL | ferritin, light polypeptide | -0.0688819 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0676927 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0646531 |
| TPM4 | tropomyosin 4 | -0.0641117 |
| VIM | vimentin | -0.0641052 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0622448 |
| PGK1 | phosphoglycerate kinase 1 | -0.0569685 |
| RPL35A | ribosomal protein L35a | -0.0535508 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0519907 |
| GOLGA4 | golgin A4 | -0.0505518 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0499493 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0495646 |
| HMGA1 | high mobility group AT-hook 1 | -0.0493055 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0469127 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0462216 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0451572 |
| GNAS | GNAS complex locus | -0.0444767 |
| CLMP | CXADR-like membrane protein | -0.0443795 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0437341 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.043176 |
| FAM107B | family with sequence similarity 107, member B | -0.0423628 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0421244 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0410928 |
| TMSB10 | thymosin beta 10 | -0.0406067 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0405084 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0400734 |
| KLK10 | kallikrein-related peptidase 10 | -0.039687 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0394768 |
| MTDH | metadherin | -0.0393022 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0388659 |
| TRRAP | transformation/transcription domain-associated protein | -0.038361 |
| MXD1 | MAX dimerization protein 1 | -0.0382436 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0377106 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0371817 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0352235 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0350241 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0348631 |
| UPP1 | uridine phosphorylase 1 | -0.034733 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0338968 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0338706 |
| CALU | calumenin | -0.0338509 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0328666 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0323872 |
| SRP54 | signal recognition particle 54kDa | -0.0321365 |
| RPS8 | ribosomal protein S8 | -0.0312929 |
| CD164 | CD164 molecule, sialomucin | -0.0312736 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0306325 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0306176 |
| TAOK3 | TAO kinase 3 | -0.0302724 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0298091 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.029491 |
| LMO7 | LIM domain 7 | -0.0291315 |
| RPLP1 | ribosomal protein, large, P1 | -0.0291051 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0284829 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0284808 |
| IKBIP | IKBKB interacting protein | -0.0280576 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0279261 |
| RPL34 | ribosomal protein L34 | -0.0276905 |
| S100A11 | S100 calcium binding protein A11 | -0.0276704 |
| THOC2 | THO complex 2 | -0.0276694 |
| THBD | thrombomodulin | -0.0275631 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.027331 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0267276 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0265491 |
| SEPTIN7 | septin 7 | -0.0263085 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0262685 |
| TMEM165 | transmembrane protein 165 | -0.0262524 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0261031 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0260835 |
| CLINT1 | clathrin interactor 1 | -0.026081 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0260481 |
| PTMA | prothymosin, alpha | -0.0259859 |
| NOP58 | NOP58 ribonucleoprotein | -0.0256399 |
| S100A6 | S100 calcium binding protein A6 | -0.0255827 |
| KIF5B | kinesin family member 5B | -0.0255243 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0253417 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0253125 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0252331 |
| SLMAP | sarcolemma associated protein | -0.0251513 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0250594 |
| CANX | calnexin | -0.0250443 |
| RBM25 | RNA binding motif protein 25 | -0.0249017 |
| RPL31 | ribosomal protein L31 | -0.0248748 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0248337 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.024728 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0247256 |
| CEP350 | centrosomal protein 350kDa | -0.0247009 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0246273 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0244348 |
