| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0646846 |
| CLTC | clathrin, heavy chain (Hc) | 0.0383501 |
| CEP250 | centrosomal protein 250kDa | 0.0308327 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0240879 |
| CDK12 | cyclin-dependent kinase 12 | 0.0232141 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0210424 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0201019 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0192389 |
| PLEC | plectin | 0.0191002 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0189906 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0189583 |
| VEGFA | vascular endothelial growth factor A | 0.0188834 |
| DIAPH1 | diaphanous-related formin 1 | 0.0178436 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0173337 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0171651 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0171432 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0170465 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0169829 |
| APP | amyloid beta (A4) precursor protein | 0.016787 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0167794 |
| SET | SET nuclear proto-oncogene | 0.0167616 |
| NTN4 | netrin 4 | 0.0157078 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0156103 |
| TMSB4X | thymosin beta 4, X-linked | 0.0154881 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0153229 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0152162 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.0147797 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0145123 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0144967 |
| MAP7 | microtubule-associated protein 7 | 0.0138922 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0136825 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0136334 |
| DSPP | dentin sialophosphoprotein | 0.0135601 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0132887 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.01296 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.0129403 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0129156 |
| SMYD3 | SET and MYND domain containing 3 | 0.0125279 |
| RPL3 | ribosomal protein L3 | 0.0124538 |
| LRRC59 | leucine rich repeat containing 59 | 0.0123598 |
| VCP | valosin containing protein | 0.0122991 |
| TPM3 | tropomyosin 3 | 0.0119975 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0119484 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0114844 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0111393 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | 0.0109959 |
| KLC1 | kinesin light chain 1 | 0.0108902 |
| KRT8 | keratin 8, type II | 0.0108715 |
| OSMR | oncostatin M receptor | 0.0107615 |
| KRT18 | keratin 18, type I | 0.0106375 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0105352 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0105133 |
| SEPTIN9 | septin 9 | 0.0103976 |
| EFNA5 | ephrin-A5 | 0.0103088 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0102887 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0102186 |
| HMGB2 | high mobility group box 2 | 0.0101805 |
| FAM219A | family with sequence similarity 219, member A | 0.0100053 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.00998684 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00996683 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.00996544 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.00994122 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.00991148 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00987619 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.00987133 |
| RAD21 | RAD21 homolog (S. pombe) | 0.00984389 |
| ADAR | adenosine deaminase, RNA-specific | 0.00979598 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00977691 |
| PRRC2C | proline-rich coiled-coil 2C | 0.00971679 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00966078 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.00952309 |
| MYOF | myoferlin | 0.00946648 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00945863 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00943996 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00940279 |
| LOC112694756 | uncharaterized LOC112694756 | 0.00937878 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00937132 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.00933466 |
| INSR | insulin receptor | 0.00932537 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00909839 |
| MYO5B | myosin VB | 0.00909291 |
| MMP24OS | MMP24 opposite strand | 0.00907125 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00898934 |
| PNN | pinin, desmosome associated protein | 0.00886185 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.00880891 |
| PMM2 | phosphomannomutase 2 | 0.00878389 |
| NABP1 | nucleic acid binding protein 1 | 0.0087712 |
| H1-0 | H1.0 linker histone | 0.00876603 |
| ENAH | enabled homolog (Drosophila) | 0.00872561 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.00872087 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.00869083 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0086583 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.00865117 |
| CEP95 | centrosomal protein 95kDa | 0.00856971 |
| ACTN1 | actinin, alpha 1 | 0.0085241 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00827572 |
| PLSCR1 | phospholipid scramblase 1 | 0.00822062 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.00819645 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.00816817 |
| ZSWIM4 | zinc finger, SWIM-type containing 4 | 0.00815424 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.110675 |
| RPL19 | ribosomal protein L19 | -0.0574897 |
| PTMA | prothymosin, alpha | -0.0551673 |
| RPL35A | ribosomal protein L35a | -0.0435409 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0388923 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0372312 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0319221 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0291399 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0283002 |
| RUNX1 | runt-related transcription factor 1 | -0.0276465 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0263636 |
| VMP1 | vacuole membrane protein 1 | -0.0257782 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.025059 |
| NDRG1 | N-myc downstream regulated 1 | -0.0238437 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0222103 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0212265 |
| RPS29 | ribosomal protein S29 | -0.0207709 |
| RPL31 | ribosomal protein L31 | -0.0195792 |
| RPL37A | ribosomal protein L37a | -0.0192999 |
| MT2A | metallothionein 2A | -0.0190139 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0189063 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0186429 |
| RPLP1 | ribosomal protein, large, P1 | -0.0184857 |
| TMEM123 | transmembrane protein 123 | -0.0181187 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0179177 |
| TMSB10 | thymosin beta 10 | -0.0177335 |
| SHROOM3 | shroom family member 3 | -0.0176709 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0176562 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0175485 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0172705 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0172522 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0167581 |
| RPS8 | ribosomal protein S8 | -0.0160583 |
| FTL | ferritin, light polypeptide | -0.0153722 |
| CCND1 | cyclin D1 | -0.0150834 |
| RPS6 | ribosomal protein S6 | -0.0148527 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0148128 |
| POTEF | POTE ankyrin domain family, member F | -0.0147809 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0147776 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0146871 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0146494 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0143196 |
| RPS13 | ribosomal protein S13 | -0.0139462 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0138573 |
| RPS20 | ribosomal protein S20 | -0.0136057 |
| GNAS | GNAS complex locus | -0.0134945 |
| RPL34 | ribosomal protein L34 | -0.0132463 |
| RPS15 | ribosomal protein S15 | -0.0132183 |
| GRB10 | growth factor receptor-bound protein 10 | -0.013195 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0128085 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.012774 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0127557 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0127234 |
| RPS16 | ribosomal protein S16 | -0.012557 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0124563 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0123632 |
| RPS3 | ribosomal protein S3 | -0.0123428 |
| RPS19 | ribosomal protein S19 | -0.0123349 |
| RPLP2 | ribosomal protein, large, P2 | -0.0123345 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0121749 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0121264 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | -0.0119969 |
| ANXA2 | annexin A2 | -0.0118592 |
| RPS24 | ribosomal protein S24 | -0.0118408 |
| AGR2 | anterior gradient 2 | -0.0116043 |
| RPL12 | ribosomal protein L12 | -0.0112894 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0112662 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0111188 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.011028 |
| FASN | fatty acid synthase | -0.0109617 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0108736 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0108207 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0107825 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0107404 |
| RPS14 | ribosomal protein S14 | -0.0107246 |
| RPS10 | ribosomal protein S10 | -0.0107186 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0104909 |
| RPS23 | ribosomal protein S23 | -0.0103425 |
| ACTG1 | actin gamma 1 | -0.0103036 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0102357 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.010186 |
| RPL36 | ribosomal protein L36 | -0.0101515 |
| RTN3 | reticulon 3 | -0.0101275 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -0.00995164 |
| TOP1 | topoisomerase (DNA) I | -0.00994766 |
| NEBL | nebulette | -0.00987821 |
| SMIM14 | small integral membrane protein 14 | -0.00986717 |
| FDPS | farnesyl diphosphate synthase | -0.00977583 |
| RPS25 | ribosomal protein S25 | -0.00970843 |
| GRHL1 | grainyhead-like 1 (Drosophila) | -0.00969487 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.00967934 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00967302 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00958523 |
| RPL7 | ribosomal protein L7 | -0.00956132 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00954495 |
| DENND1A | DENN/MADD domain containing 1A | -0.00937106 |
| RPL9 | ribosomal protein L9 | -0.00933036 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00932812 |
| CD9 | CD9 molecule | -0.0093184 |
| MIEN1 | migration and invasion enhancer 1 | -0.00931288 |
