| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.173036 |
| APOL1 | apolipoprotein L, 1 | 0.158432 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.145529 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.124293 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.114803 |
| ASPH | aspartate beta-hydroxylase | 0.112026 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.10904 |
| LAMC2 | laminin, gamma 2 | 0.101892 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.101483 |
| APP | amyloid beta (A4) precursor protein | 0.0770264 |
| TMSB4X | thymosin beta 4, X-linked | 0.0725086 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0722802 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0633929 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0629781 |
| LAMA4 | laminin, alpha 4 | 0.0619992 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0614823 |
| CD2AP | CD2-associated protein | 0.0614572 |
| TMSB10 | thymosin beta 10 | 0.0610396 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0605451 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0591617 |
| EGR1 | early growth response 1 | 0.0588542 |
| KRT19 | keratin 19, type I | 0.0581674 |
| NRG3 | neuregulin 3 | 0.0576665 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0573148 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0571626 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0571548 |
| BICC1 | BicC family RNA binding protein 1 | 0.0565793 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0563027 |
| BCL2L1 | BCL2-like 1 | 0.0545233 |
| B2M | beta-2-microglobulin | 0.0544525 |
| H1-0 | H1.0 linker histone | 0.054035 |
| MYO1E | myosin IE | 0.0527289 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0525894 |
| DST | dystonin | 0.0525826 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0514942 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.051352 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0510011 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0509759 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0507484 |
| PHF3 | PHD finger protein 3 | 0.0506682 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0496973 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0496631 |
| FAM3C | family with sequence similarity 3, member C | 0.0495965 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0469876 |
| SGMS2 | sphingomyelin synthase 2 | 0.0468039 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.046663 |
| PLEC | plectin | 0.0465875 |
| EFNA5 | ephrin-A5 | 0.0457195 |
| RNF213 | ring finger protein 213 | 0.0445869 |
| SP100 | SP100 nuclear antigen | 0.0444886 |
| VCL | vinculin | 0.0442843 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0441392 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0441146 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0434195 |
| LMO7 | LIM domain 7 | 0.043281 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0427553 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0423835 |
| NABP1 | nucleic acid binding protein 1 | 0.041382 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0413223 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0409785 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0401128 |
| RPL19 | ribosomal protein L19 | 0.0400379 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0399505 |
| TJP1 | tight junction protein 1 | 0.0392065 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0390426 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0388594 |
| NTN4 | netrin 4 | 0.0380897 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0380817 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0377456 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0375998 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0375044 |
| EHBP1 | EH domain binding protein 1 | 0.0374668 |
| RAB10 | RAB10, member RAS oncogene family | 0.0369878 |
| SVIL | supervillin | 0.0365123 |
| HDAC9 | histone deacetylase 9 | 0.0364125 |
| RASAL2 | RAS protein activator like 2 | 0.0358894 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.035838 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0358253 |
| SFTPA2 | surfactant protein A2 | 0.035156 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0348696 |
| SMYD3 | SET and MYND domain containing 3 | 0.0346513 |
| JAK1 | Janus kinase 1 | 0.0346471 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0345909 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0344732 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0340377 |
| MT1X | metallothionein 1X | 0.0339513 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0336776 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0332887 |
| CFB | complement factor B | 0.0331539 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0330196 |
| IL6ST | interleukin 6 signal transducer | 0.0321747 |
| BPTF | bromodomain PHD finger transcription factor | 0.03177 |
| OSMR | oncostatin M receptor | 0.0316012 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0315681 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0311186 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0307578 |
| TXNIP | thioredoxin interacting protein | 0.0307568 |
| AREG | amphiregulin | 0.0307303 |
| PRELID2 | PRELI domain containing 2 | 0.0306867 |
| ACTN1 | actinin, alpha 1 | 0.0306148 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.206123 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.187577 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0762734 |
| FAM13A | family with sequence similarity 13, member A | -0.0713991 |
| NDRG1 | N-myc downstream regulated 1 | -0.0679547 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0678477 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.063858 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0601638 |
| DTNA | dystrobrevin, alpha | -0.0593038 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0587753 |
| POTEF | POTE ankyrin domain family, member F | -0.0554022 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0505715 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0488653 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0488097 |
| TPM4 | tropomyosin 4 | -0.046107 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0443674 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0439955 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0420118 |
| HMGA1 | high mobility group AT-hook 1 | -0.0415765 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0398315 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0379493 |
| WDR45B | WD repeat domain 45B | -0.0377172 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0375569 |
| SRP54 | signal recognition particle 54kDa | -0.0360753 |
| MEF2A | myocyte enhancer factor 2A | -0.0345085 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0322873 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0321249 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0318421 |
| CCNY | cyclin Y | -0.0312185 |
| RREB1 | ras responsive element binding protein 1 | -0.030875 |
| FOSL1 | FOS-like antigen 1 | -0.0307542 |
| JUP | junction plakoglobin | -0.0298417 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.029834 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0258634 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0248032 |
| ACTG1 | actin gamma 1 | -0.0239677 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0238611 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0234856 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0231858 |
| SPAG9 | sperm associated antigen 9 | -0.0231054 |
| TMEM165 | transmembrane protein 165 | -0.0228441 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0228328 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0223127 |
| INSIG1 | insulin induced gene 1 | -0.0219635 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0218917 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0214398 |
| CDCP1 | CUB domain containing protein 1 | -0.0213405 |
| RNF149 | ring finger protein 149 | -0.0212981 |
| FDPS | farnesyl diphosphate synthase | -0.0209123 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0203628 |
| HLA-A | major histocompatibility complex, class I, A | -0.0203487 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0203399 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0197409 |
| PKM | pyruvate kinase, muscle | -0.0195272 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0194053 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0193141 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | -0.019194 |
| FAM117B | family with sequence similarity 117, member B | -0.0191303 |
| RBM39 | RNA binding motif protein 39 | -0.0187397 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0186567 |
| PGK1 | phosphoglycerate kinase 1 | -0.0185637 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0182666 |
| RNF24 | ring finger protein 24 | -0.0181659 |
| HELZ | helicase with zinc finger | -0.0180503 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0179836 |
| SNX9 | sorting nexin 9 | -0.0179284 |
| VIM | vimentin | -0.0178922 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0178087 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0177937 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0177863 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0176063 |
| RLF | rearranged L-myc fusion | -0.0174361 |
| S100A11 | S100 calcium binding protein A11 | -0.0174013 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0173895 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.017164 |
| FA2H | fatty acid 2-hydroxylase | -0.0171363 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0171298 |
| RAI1 | retinoic acid induced 1 | -0.016842 |
| NCKAP5 | NCK-associated protein 5 | -0.0167917 |
| RAI14 | retinoic acid induced 14 | -0.0165989 |
| MXD1 | MAX dimerization protein 1 | -0.0165745 |
| RPL35A | ribosomal protein L35a | -0.01655 |
| USP37 | ubiquitin specific peptidase 37 | -0.0163477 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0162365 |
| ITGB4 | integrin, beta 4 | -0.0158984 |
| COPA | coatomer protein complex, subunit alpha | -0.0157811 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0157502 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0157494 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | -0.0156314 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0155995 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0155718 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0155671 |
| MACO1 | macoilin 1 | -0.0155468 |
| RIOK3 | RIO kinase 3 | -0.0154608 |
| IGF2 | insulin-like growth factor 2 | -0.0154527 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0152582 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0152295 |
| MLKL | mixed lineage kinase domain-like | -0.0152292 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0151182 |
| PROSER2 | proline and serine rich 2 | -0.0150237 |
