| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.182586 |
| VCL | vinculin | 0.150168 |
| TLE4 | transducin-like enhancer of split 4 | 0.134855 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.120484 |
| EXT1 | exostosin glycosyltransferase 1 | 0.107836 |
| NRG1 | neuregulin 1 | 0.101971 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0860907 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0829002 |
| RNF213 | ring finger protein 213 | 0.0735444 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0660654 |
| COL3A1 | collagen, type III, alpha 1 | 0.0628314 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0615311 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0583759 |
| RIGI | RNA sensor RIG-I | 0.0582868 |
| PRKCA | protein kinase C, alpha | 0.0563666 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0549277 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0541657 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0531377 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0522802 |
| FAM107B | family with sequence similarity 107, member B | 0.0510955 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0506566 |
| COL1A1 | collagen, type I, alpha 1 | 0.0498815 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0498319 |
| TPM1 | tropomyosin 1 (alpha) | 0.0491194 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0486128 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.048121 |
| SP100 | SP100 nuclear antigen | 0.0463983 |
| ACTN1 | actinin, alpha 1 | 0.0444113 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0441534 |
| TRIB2 | tribbles pseudokinase 2 | 0.0439807 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0439218 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0438246 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0435799 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0433672 |
| DST | dystonin | 0.0432584 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0428896 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.042669 |
| EXOC4 | exocyst complex component 4 | 0.042598 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0415962 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0414717 |
| SEPTIN9 | septin 9 | 0.0409435 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0407584 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0404401 |
| AOPEP | aminopeptidase O (putative) | 0.0398313 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.039705 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0388898 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0378773 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0372127 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0368264 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0366615 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0360001 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0357723 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0357327 |
| NRP1 | neuropilin 1 | 0.0356729 |
| DNM3 | dynamin 3 | 0.0351816 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0347082 |
| ACTG1 | actin gamma 1 | 0.0345305 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0330767 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0330227 |
| RPL23 | ribosomal protein L23 | 0.032897 |
| KLHL13 | kelch-like family member 13 | 0.0325849 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0324376 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0323188 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0320411 |
| THBS1 | thrombospondin 1 | 0.0316069 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.031497 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0310987 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0308442 |
| FRMD4A | FERM domain containing 4A | 0.0306363 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0305669 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0302089 |
| ZNF804A | zinc finger protein 804A | 0.0299235 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0297569 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0297299 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0297015 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0295157 |
| MRTFA | myocardin related transcription factor A | 0.0289949 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0284449 |
| MYO6 | myosin VI | 0.0283882 |
| GLCCI1 | glucocorticoid induced 1 | 0.028313 |
| PLPP1 | phospholipid phosphatase 1 | 0.028209 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.02809 |
| LMNA | lamin A/C | 0.0278321 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0276825 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0276564 |
| BPTF | bromodomain PHD finger transcription factor | 0.0273287 |
| PCBP3 | poly(rC) binding protein 3 | 0.0272298 |
| MX2 | MX dynamin-like GTPase 2 | 0.0270452 |
| KLF6 | Kruppel-like factor 6 | 0.0268092 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0267501 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0267243 |
| CCDC57 | coiled-coil domain containing 57 | 0.0266869 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0266359 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0265731 |
| MALT1 | MALT1 paracaspase | 0.0265041 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0260668 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0259976 |
| VGF | VGF nerve growth factor inducible | 0.0259973 |
| RAD51B | RAD51 paralog B | 0.0259832 |
| TRIM24 | tripartite motif containing 24 | 0.0259799 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.428088 |
| IGF2 | insulin-like growth factor 2 | -0.134609 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0433317 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0401318 |
| PCBP2 | poly(rC) binding protein 2 | -0.0378951 |
| POTEF | POTE ankyrin domain family, member F | -0.0334372 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0331341 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0320034 |
| GOLGA4 | golgin A4 | -0.0279808 |
| CDC27 | cell division cycle 27 | -0.0277614 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0270176 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0254876 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0254053 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0249545 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0245648 |
| NDRG1 | N-myc downstream regulated 1 | -0.0238572 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0232848 |
| LDHB | lactate dehydrogenase B | -0.0226807 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0225644 |
| HELZ | helicase with zinc finger | -0.0225407 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0221855 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0214907 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0212193 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0203793 |
| MMP2 | matrix metallopeptidase 2 | -0.0200877 |
| RNF145 | ring finger protein 145 | -0.0200818 |
| PCDH9 | protocadherin 9 | -0.0200805 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0199883 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0194678 |
| USP3 | ubiquitin specific peptidase 3 | -0.0193974 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0192879 |
| FNBP4 | formin binding protein 4 | -0.018901 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0181071 |
| CCNL1 | cyclin L1 | -0.0180643 |
| PKM | pyruvate kinase, muscle | -0.0179399 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0179266 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0178884 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0178324 |
| HMGA1 | high mobility group AT-hook 1 | -0.0175413 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.017499 |
| PRTG | protogenin | -0.0173918 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0170229 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0169652 |
| SRP54 | signal recognition particle 54kDa | -0.0168341 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.016729 |
| CDK19 | cyclin-dependent kinase 19 | -0.0166703 |
| LRRC58 | leucine rich repeat containing 58 | -0.0166442 |
| FOXO1 | forkhead box O1 | -0.0165219 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0161317 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0160297 |
| SETD5 | SET domain containing 5 | -0.0160167 |
| MEIS2 | Meis homeobox 2 | -0.0158222 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0157559 |
| ANGPT1 | angiopoietin 1 | -0.0157416 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0157403 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0155474 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0155268 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0155181 |
| UBE3A | ubiquitin protein ligase E3A | -0.0154164 |
| NUP58 | nucleoporin 58 | -0.0153684 |
| TCERG1 | transcription elongation regulator 1 | -0.0153598 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.015262 |
| PHIP | pleckstrin homology domain interacting protein | -0.015046 |
| DYM | dymeclin | -0.015044 |
| SCFD2 | sec1 family domain containing 2 | -0.0149612 |
| TMEM165 | transmembrane protein 165 | -0.0148577 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0148252 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0147798 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0146735 |
| NOP58 | NOP58 ribonucleoprotein | -0.0146716 |
| ARRDC3 | arrestin domain containing 3 | -0.0143656 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0143614 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -0.0141728 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | -0.0141554 |
| CDON | cell adhesion associated, oncogene regulated | -0.0140913 |
| UBXN7 | UBX domain protein 7 | -0.0139499 |
| CADM2 | cell adhesion molecule 2 | -0.0138298 |
| MORF4L2 | mortality factor 4 like 2 | -0.0137692 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0137451 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | -0.0137348 |
| INSIG2 | insulin induced gene 2 | -0.0136191 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0136174 |
| WDR45B | WD repeat domain 45B | -0.0136032 |
| RTN4 | reticulon 4 | -0.0136004 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0135935 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.0135443 |
| CRH | corticotropin releasing hormone | -0.0134389 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0134201 |
| RFX7 | regulatory factor X, 7 | -0.0134187 |
| HMGB2 | high mobility group box 2 | -0.0133166 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0132131 |
| FHIP2A | FHF complex subunit HOOK interacting protein 2A | -0.013085 |
| ZNF654 | zinc finger protein 654 | -0.0130428 |
| RBM26 | RNA binding motif protein 26 | -0.0129808 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0129719 |
| EPHA3 | EPH receptor A3 | -0.0127171 |
| MAP1B | microtubule-associated protein 1B | -0.0126493 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0126226 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0125757 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 | -0.0125598 |
