| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFNGR1 | interferon gamma receptor 1 | 0.0625642 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0566993 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0517478 |
| SMAD3 | SMAD family member 3 | 0.0466477 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0362553 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0347656 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0323636 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0301575 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0301399 |
| DST | dystonin | 0.0283315 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0273799 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0271029 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0266442 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0238132 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0232635 |
| BCL2L1 | BCL2-like 1 | 0.0232138 |
| PDZD8 | PDZ domain containing 8 | 0.0226655 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0222753 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0221354 |
| VEGFA | vascular endothelial growth factor A | 0.0219349 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0213279 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0212146 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0208589 |
| RPS2 | ribosomal protein S2 | 0.0205352 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0204105 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0203544 |
| SBF2 | SET binding factor 2 | 0.0202966 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0193672 |
| SEPTIN9 | septin 9 | 0.0192529 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0191906 |
| TMEM51 | transmembrane protein 51 | 0.0190124 |
| MAP7 | microtubule-associated protein 7 | 0.0186661 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0182508 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0180673 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.0175829 |
| ATP10B | ATPase, class V, type 10B | 0.0174527 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0173353 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0169124 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0168661 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0166819 |
| APOL1 | apolipoprotein L, 1 | 0.0165308 |
| RNF145 | ring finger protein 145 | 0.016466 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.016388 |
| APOL2 | apolipoprotein L, 2 | 0.0160299 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0159088 |
| YAP1 | Yes-associated protein 1 | 0.0158248 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0156491 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0156088 |
| BRD4 | bromodomain containing 4 | 0.015598 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0154558 |
| ASPH | aspartate beta-hydroxylase | 0.0152352 |
| SLTM | SAFB-like, transcription modulator | 0.0145286 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0145191 |
| YBX3 | Y box binding protein 3 | 0.0144877 |
| IL20RA | interleukin 20 receptor, alpha | 0.0144638 |
| TC2N | tandem C2 domains, nuclear | 0.0143528 |
| XDH | xanthine dehydrogenase | 0.014309 |
| NCKAP1 | NCK-associated protein 1 | 0.0142948 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0142441 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0142164 |
| CLTC | clathrin, heavy chain (Hc) | 0.0142148 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0140429 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0140214 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0136522 |
| SFTPA2 | surfactant protein A2 | 0.0136115 |
| CKLF | chemokine-like factor | 0.0134503 |
| CYTH1 | cytohesin 1 | 0.0133985 |
| SPICE1 | spindle and centriole associated protein 1 | 0.0133847 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.0133137 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.0133055 |
| ABHD17C | abhydrolase domain containing 17C | 0.0131564 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0131527 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0131479 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0131414 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0131121 |
| DNM2 | dynamin 2 | 0.0130105 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.012995 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0129547 |
| PHF3 | PHD finger protein 3 | 0.0129387 |
| FGD5 | FYVE, RhoGEF and PH domain containing 5 | 0.0129246 |
| EFHD2 | EF-hand domain family, member D2 | 0.0128823 |
| MRPS10 | mitochondrial ribosomal protein S10 | 0.0128245 |
| FHL2 | four and a half LIM domains 2 | 0.0127934 |
| IL6ST | interleukin 6 signal transducer | 0.0127909 |
| PRSS3 | protease, serine, 3 | 0.0127862 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0127217 |
| WAPL | WAPL cohesin release factor | 0.0126898 |
| USP47 | ubiquitin specific peptidase 47 | 0.0126417 |
| CDCP1 | CUB domain containing protein 1 | 0.0126299 |
| PNN | pinin, desmosome associated protein | 0.0126135 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0124251 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0123649 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) | 0.0123174 |
| DSG2 | desmoglein 2 | 0.0122751 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0122028 |
| SKI | SKI proto-oncogene | 0.0121878 |
| TMEM154 | transmembrane protein 154 | 0.0121845 |
| ADAR | adenosine deaminase, RNA-specific | 0.0120859 |
| SP3 | Sp3 transcription factor | 0.012064 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.012064 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.231554 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.157506 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.108444 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100424 |
| RNF213 | ring finger protein 213 | -0.0975025 |
| B2M | beta-2-microglobulin | -0.0943569 |
| PKM | pyruvate kinase, muscle | -0.0942799 |
| JUN | jun proto-oncogene | -0.0938404 |
| ENO1 | enolase 1, (alpha) | -0.0935724 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0926563 |
| PERP | PERP, TP53 apoptosis effector | -0.0895438 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0868772 |
| AHNAK | AHNAK nucleoprotein | -0.0866713 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0863617 |
| PTMA | prothymosin, alpha | -0.0834465 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0734117 |
| INTS6 | integrator complex subunit 6 | -0.0728838 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0721347 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0710463 |
| MX1 | MX dynamin-like GTPase 1 | -0.0709835 |
| CALR | calreticulin | -0.067655 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0667576 |
| EGR1 | early growth response 1 | -0.065646 |
| ANXA2 | annexin A2 | -0.0638651 |
| RPL23 | ribosomal protein L23 | -0.0635951 |
| PLSCR1 | phospholipid scramblase 1 | -0.0631923 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0628822 |
| CANX | calnexin | -0.0627301 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0617758 |
| RIGI | RNA sensor RIG-I | -0.0615567 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0614399 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0610975 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0606862 |
| SP100 | SP100 nuclear antigen | -0.0604198 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0597614 |
| LYZ | lysozyme | -0.058424 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0558952 |
| TMSB10 | thymosin beta 10 | -0.0553364 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0522603 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0518843 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0515552 |
| PCBP2 | poly(rC) binding protein 2 | -0.0505105 |
| HLA-B | major histocompatibility complex, class I, B | -0.0496245 |
| VMP1 | vacuole membrane protein 1 | -0.0495042 |
| NPSR1 | neuropeptide S receptor 1 | -0.0490946 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0478181 |
| HLA-E | major histocompatibility complex, class I, E | -0.0477638 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0477227 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0476474 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0476324 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0473763 |
| SQSTM1 | sequestosome 1 | -0.046295 |
| LCN2 | lipocalin 2 | -0.0458629 |
| MX2 | MX dynamin-like GTPase 2 | -0.0451767 |
| POTEF | POTE ankyrin domain family, member F | -0.0442946 |
| EZR | ezrin | -0.0410671 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0409519 |
| RPS27A | ribosomal protein S27a | -0.04057 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0404759 |
| PRKCA | protein kinase C, alpha | -0.0394548 |
| CALU | calumenin | -0.0386296 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0384754 |
| ACTN4 | actinin, alpha 4 | -0.0383039 |
| LDHA | lactate dehydrogenase A | -0.0374804 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0373596 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0364618 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0363835 |
| LOC112694756 | uncharaterized LOC112694756 | -0.035896 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0357933 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0354153 |
| ZNF207 | zinc finger protein 207 | -0.0350482 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0349442 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0348445 |
| IRS2 | insulin receptor substrate 2 | -0.0347193 |
| HLA-C | major histocompatibility complex, class I, C | -0.0345837 |
| CDHR2 | cadherin-related family member 2 | -0.0339717 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0338468 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0336565 |
| SPAG9 | sperm associated antigen 9 | -0.0334693 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0325879 |
| GNAS | GNAS complex locus | -0.0325874 |
| S100A10 | S100 calcium binding protein A10 | -0.0324694 |
| HLA-A | major histocompatibility complex, class I, A | -0.0324135 |
| MECOM | MDS1 and EVI1 complex locus | -0.0323845 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0322348 |
| S100A6 | S100 calcium binding protein A6 | -0.0320914 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0320783 |
| MSI2 | musashi RNA-binding protein 2 | -0.0320462 |
| PGK1 | phosphoglycerate kinase 1 | -0.0319032 |
| IRF1 | interferon regulatory factor 1 | -0.0313322 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0311092 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0307937 |
| RRBP1 | ribosome binding protein 1 | -0.0307406 |
| EPCAM | epithelial cell adhesion molecule | -0.0306095 |
| RUNX1 | runt-related transcription factor 1 | -0.0305896 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0304044 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0303348 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0299487 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0297452 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0292039 |
