| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.132647 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0992344 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0986653 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0596049 |
| PLEC | plectin | 0.0568427 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.056833 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0568159 |
| HYOU1 | hypoxia up-regulated 1 | 0.0533997 |
| MT2A | metallothionein 2A | 0.0444216 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0377792 |
| STK17A | serine/threonine kinase 17a | 0.035505 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0339196 |
| HDAC4 | histone deacetylase 4 | 0.0327285 |
| PRELID2 | PRELI domain containing 2 | 0.0317081 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0293209 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0290508 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0288054 |
| RPL3 | ribosomal protein L3 | 0.0277737 |
| RPL11 | ribosomal protein L11 | 0.0275992 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.027279 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0269715 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0269142 |
| SQSTM1 | sequestosome 1 | 0.0268277 |
| NAV1 | neuron navigator 1 | 0.0264675 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0262137 |
| CALN1 | calneuron 1 | 0.0257782 |
| MT1X | metallothionein 1X | 0.0257763 |
| INTS6 | integrator complex subunit 6 | 0.0252297 |
| CEP128 | centrosomal protein 128kDa | 0.0248858 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.024848 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0237582 |
| TXNRD1 | thioredoxin reductase 1 | 0.0234413 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0232526 |
| H1-4 | H1.4 linker histone, cluster member | 0.0230403 |
| FUS | FUS RNA binding protein | 0.0227313 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0226454 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0224156 |
| H1-2 | H1.2 linker histone, cluster member | 0.0221678 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0220742 |
| FAM219A | family with sequence similarity 219, member A | 0.0220222 |
| KLHL29 | kelch-like family member 29 | 0.0218537 |
| RPL35 | ribosomal protein L35 | 0.0218222 |
| ACTN1 | actinin, alpha 1 | 0.0217382 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0215654 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0212318 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0211644 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0209888 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0208564 |
| WWOX | WW domain containing oxidoreductase | 0.0207401 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0207166 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0205295 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0203596 |
| SFTPA2 | surfactant protein A2 | 0.0202486 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0200275 |
| ASPH | aspartate beta-hydroxylase | 0.019869 |
| FTL | ferritin, light polypeptide | 0.0198045 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0197528 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0197057 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0196493 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0194469 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0193609 |
| BRD2 | bromodomain containing 2 | 0.0193363 |
| CREBBP | CREB binding protein | 0.0192829 |
| MCL1 | myeloid cell leukemia 1 | 0.0191382 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0191243 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0189058 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0187079 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0187069 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0186966 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0183264 |
| RPS2 | ribosomal protein S2 | 0.0182199 |
| CD44 | CD44 molecule (Indian blood group) | 0.0180064 |
| C3 | complement component 3 | 0.0180059 |
| STC1 | stanniocalcin 1 | 0.0179327 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0178903 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0178816 |
| COL6A1 | collagen, type VI, alpha 1 | 0.017727 |
| SKI | SKI proto-oncogene | 0.017712 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0176532 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0173786 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0171394 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0171236 |
| PCBP3 | poly(rC) binding protein 3 | 0.0170307 |
| SMYD3 | SET and MYND domain containing 3 | 0.0169215 |
| RPS21 | ribosomal protein S21 | 0.0169201 |
| SEM1 | SEM1 26S proteasome subunit | 0.0168953 |
| C1R | complement component 1, r subcomponent | 0.0168399 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0167286 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.0166216 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0165774 |
| MSN | moesin | 0.0165193 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0164388 |
| TPD52 | tumor protein D52 | 0.0164031 |
| FLNA | filamin A, alpha | 0.0163984 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0162154 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0161542 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0160881 |
| CEP112 | centrosomal protein 112kDa | 0.0159348 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0158967 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0158712 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.396851 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.145036 |
| GRB10 | growth factor receptor-bound protein 10 | -0.13155 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.11318 |
| TPM4 | tropomyosin 4 | -0.109953 |
| LOX | lysyl oxidase | -0.107111 |
| FN1 | fibronectin 1 | -0.100427 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0964924 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.095227 |
| CADM1 | cell adhesion molecule 1 | -0.0923015 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0915124 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.08638 |
| EGFR | epidermal growth factor receptor | -0.0856569 |
| DST | dystonin | -0.083396 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0734111 |
| INHBA | inhibin, beta A | -0.0734076 |
| PGK1 | phosphoglycerate kinase 1 | -0.0704276 |
| SBF2 | SET binding factor 2 | -0.0695945 |
| VIM | vimentin | -0.0678338 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0674822 |
| TNS3 | tensin 3 | -0.0576492 |
| TNNC1 | troponin C type 1 (slow) | -0.0536736 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0533537 |
| SPAG9 | sperm associated antigen 9 | -0.0531734 |
| AFAP1 | actin filament associated protein 1 | -0.0515063 |
| GOLGB1 | golgin B1 | -0.0515027 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0512887 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0506881 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0493784 |
| NDRG1 | N-myc downstream regulated 1 | -0.0482778 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0460444 |
| LDHA | lactate dehydrogenase A | -0.0459112 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0458987 |
| AHNAK | AHNAK nucleoprotein | -0.0452479 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0451537 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0443601 |
| ANTXR2 | anthrax toxin receptor 2 | -0.043258 |
| CANX | calnexin | -0.0420728 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0405773 |
| ENO1 | enolase 1, (alpha) | -0.0405153 |
| MMP12 | matrix metallopeptidase 12 | -0.0400082 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0394098 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0391299 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0380383 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0380164 |
| GDF15 | growth differentiation factor 15 | -0.037702 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0375201 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0373601 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0370857 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0370441 |
| RTN4 | reticulon 4 | -0.036759 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0365774 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0362052 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0359117 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0358759 |
| WASF2 | WAS protein family, member 2 | -0.0353722 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0350193 |
| IGF2 | insulin-like growth factor 2 | -0.0338595 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0337463 |
| GOLGA4 | golgin A4 | -0.0336012 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0334494 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0332633 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0332333 |
| NBEAL1 | neurobeachin-like 1 | -0.0332267 |
| LRRC49 | leucine rich repeat containing 49 | -0.0331231 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.032495 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0323726 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.032123 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0321164 |
| CREB5 | cAMP responsive element binding protein 5 | -0.031896 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0317546 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.031723 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0312619 |
| RIGI | RNA sensor RIG-I | -0.0309903 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0308524 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0305889 |
| CALD1 | caldesmon 1 | -0.0305809 |
| RAI14 | retinoic acid induced 14 | -0.0304327 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0302562 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0300976 |
| SRP54 | signal recognition particle 54kDa | -0.0300154 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0294234 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0293924 |
| CD109 | CD109 molecule | -0.0292485 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0292244 |
| FNDC3B | fibronectin type III domain containing 3B | -0.029164 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0289315 |
| COG5 | component of oligomeric golgi complex 5 | -0.0288121 |
| OSMR | oncostatin M receptor | -0.028777 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0284935 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0284849 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0284848 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0278594 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0278521 |
| SMAD3 | SMAD family member 3 | -0.0278234 |
| HM13 | histocompatibility (minor) 13 | -0.0276308 |
| RBM39 | RNA binding motif protein 39 | -0.0273439 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0271928 |
| PDE10A | phosphodiesterase 10A | -0.0270895 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0268654 |
