| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.105274 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0739781 |
| PLEC | plectin | 0.0618706 |
| KRT8 | keratin 8, type II | 0.0598925 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0554261 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.051834 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0488232 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0479949 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0479712 |
| RPL3 | ribosomal protein L3 | 0.0453981 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0451981 |
| HYOU1 | hypoxia up-regulated 1 | 0.0448945 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0444495 |
| TJP1 | tight junction protein 1 | 0.0418146 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0398615 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0395855 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0382445 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0374375 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0368114 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0355095 |
| FLNA | filamin A, alpha | 0.0353932 |
| HELZ | helicase with zinc finger | 0.0352801 |
| DIAPH1 | diaphanous-related formin 1 | 0.0348531 |
| CTBP2 | C-terminal binding protein 2 | 0.0345058 |
| PCBP2 | poly(rC) binding protein 2 | 0.0343974 |
| TENM3 | teneurin transmembrane protein 3 | 0.0338203 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0332132 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0327249 |
| GSE1 | Gse1 coiled-coil protein | 0.0321499 |
| SEPTIN9 | septin 9 | 0.031297 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0312951 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0299209 |
| PRELID2 | PRELI domain containing 2 | 0.0291978 |
| SEPTIN2 | septin 2 | 0.0285078 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0283332 |
| PCDH7 | protocadherin 7 | 0.0281119 |
| KLC1 | kinesin light chain 1 | 0.0280045 |
| HDLBP | high density lipoprotein binding protein | 0.0276049 |
| WWOX | WW domain containing oxidoreductase | 0.0275523 |
| KRT18 | keratin 18, type I | 0.0272752 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0267608 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0264015 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0261827 |
| LOC112694756 | uncharaterized LOC112694756 | 0.025954 |
| EXOC6B | exocyst complex component 6B | 0.0258356 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0255674 |
| H1-4 | H1.4 linker histone, cluster member | 0.0255115 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0249976 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0249827 |
| WWC1 | WW and C2 domain containing 1 | 0.0244899 |
| TXNRD1 | thioredoxin reductase 1 | 0.0242602 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0239523 |
| INTS6 | integrator complex subunit 6 | 0.0238653 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0237703 |
| GOLGA4 | golgin A4 | 0.022847 |
| EPHA2 | EPH receptor A2 | 0.0227674 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0225725 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0225134 |
| AFDN | afadin, adherens junction formation factor | 0.0222372 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0221446 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0219379 |
| ATXN1 | ataxin 1 | 0.0218337 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0217789 |
| MACROD2 | MACRO domain containing 2 | 0.0217442 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0216598 |
| PCNX2 | pecanex 2 | 0.0215994 |
| SGMS2 | sphingomyelin synthase 2 | 0.0213673 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0213638 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0212354 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0208419 |
| RCOR1 | REST corepressor 1 | 0.0205431 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0204859 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.020389 |
| RUNX1 | runt-related transcription factor 1 | 0.0203565 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.020197 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0201876 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0201797 |
| TRAM1 | translocation associated membrane protein 1 | 0.0201008 |
| MED13L | mediator complex subunit 13-like | 0.0200431 |
| ZNF638 | zinc finger protein 638 | 0.0200423 |
| MYO9B | myosin IXB | 0.0199607 |
| ATXN7 | ataxin 7 | 0.0198649 |
| UTRN | utrophin | 0.0198111 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0197973 |
| WWC2 | WW and C2 domain containing 2 | 0.019662 |
| POTEF | POTE ankyrin domain family, member F | 0.0194289 |
| CDC73 | cell division cycle 73 | 0.0193864 |
| HOMER1 | homer scaffolding protein 1 | 0.0193591 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0192663 |
| YAP1 | Yes-associated protein 1 | 0.0191815 |
| SMAD3 | SMAD family member 3 | 0.0187277 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0186977 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.0186157 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0183949 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0183461 |
| PNN | pinin, desmosome associated protein | 0.0181305 |
| DST | dystonin | 0.0180307 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0180305 |
| MIDN | midnolin | 0.018012 |
| NBAS | neuroblastoma amplified sequence | 0.0179191 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.250773 |
| NDRG1 | N-myc downstream regulated 1 | -0.120032 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.101022 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0909527 |
| RPL35A | ribosomal protein L35a | -0.0890041 |
| TPM4 | tropomyosin 4 | -0.0671352 |
| RAD51B | RAD51 paralog B | -0.0660242 |
| PGK1 | phosphoglycerate kinase 1 | -0.0630077 |
| RPS6 | ribosomal protein S6 | -0.0628129 |
| RPS8 | ribosomal protein S8 | -0.0533794 |
| PKM | pyruvate kinase, muscle | -0.0533589 |
| MYOF | myoferlin | -0.0530295 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0510796 |
| VCL | vinculin | -0.0504523 |
| RPS24 | ribosomal protein S24 | -0.0478377 |
| MKI67 | marker of proliferation Ki-67 | -0.0456901 |
| RPL34 | ribosomal protein L34 | -0.045197 |
| RPLP1 | ribosomal protein, large, P1 | -0.0445741 |
| FDPS | farnesyl diphosphate synthase | -0.0439198 |
| ASPH | aspartate beta-hydroxylase | -0.041403 |
| TMSB10 | thymosin beta 10 | -0.0409246 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0406504 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0406222 |
| ENO1 | enolase 1, (alpha) | -0.039464 |
| KPNB1 | karyopherin (importin) beta 1 | -0.039236 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0391695 |
| CANX | calnexin | -0.0376834 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0372965 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0370146 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0367491 |
| HMGB2 | high mobility group box 2 | -0.036651 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0362608 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0348494 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.034272 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0339192 |
| RPL38 | ribosomal protein L38 | -0.0334747 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0334213 |
| RPLP2 | ribosomal protein, large, P2 | -0.032674 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0326124 |
| GNAS | GNAS complex locus | -0.0319711 |
| MYO9A | myosin IXA | -0.0318422 |
| RPS27A | ribosomal protein S27a | -0.0315587 |
| RPS13 | ribosomal protein S13 | -0.0314769 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0312821 |
| RPL11 | ribosomal protein L11 | -0.0309563 |
| RPS3 | ribosomal protein S3 | -0.0306764 |
| RPL26 | ribosomal protein L26 | -0.0301848 |
| RPS25 | ribosomal protein S25 | -0.0296363 |
| RPS29 | ribosomal protein S29 | -0.0294897 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.029225 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0291818 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0289927 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0288886 |
| RPL37A | ribosomal protein L37a | -0.028846 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0281723 |
| RAD50 | RAD50 homolog (S. cerevisiae) | -0.0280966 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0279933 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0278347 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0275193 |
| RPL36A | ribosomal protein L36a | -0.0275044 |
| SERINC5 | serine incorporator 5 | -0.0274903 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0273566 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0272563 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0271384 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0271077 |
| RNF43 | ring finger protein 43 | -0.0271016 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.026842 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0266886 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0264067 |
| RPL27A | ribosomal protein L27a | -0.0263194 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0262673 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0261137 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0260448 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0258929 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0257141 |
| RPL31 | ribosomal protein L31 | -0.0255911 |
| RPS14 | ribosomal protein S14 | -0.0255196 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0251849 |
| RPL13A | ribosomal protein L13a | -0.0251059 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0250559 |
| PHF3 | PHD finger protein 3 | -0.0249691 |
| BPTF | bromodomain PHD finger transcription factor | -0.0247992 |
| EHBP1 | EH domain binding protein 1 | -0.0247921 |
| WASF2 | WAS protein family, member 2 | -0.024736 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0246964 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0246652 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0246613 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0245726 |
| EPCAM | epithelial cell adhesion molecule | -0.0245391 |
| HMGB1 | high mobility group box 1 | -0.024456 |
| ATM | ATM serine/threonine kinase | -0.0243645 |
| LDHB | lactate dehydrogenase B | -0.0241752 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0238703 |
| S100A6 | S100 calcium binding protein A6 | -0.023493 |
| THRAP3 | thyroid hormone receptor associated protein 3 | -0.023291 |
| DIAPH3 | diaphanous-related formin 3 | -0.0232899 |
| PKP2 | plakophilin 2 | -0.0231355 |
| NFIA | nuclear factor I/A | -0.0228899 |
| WDR45B | WD repeat domain 45B | -0.0227225 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0226866 |
