| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.237373 |
| VCL | vinculin | 0.101134 |
| TJP1 | tight junction protein 1 | 0.0759516 |
| WWC1 | WW and C2 domain containing 1 | 0.0740215 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0713639 |
| INTS6 | integrator complex subunit 6 | 0.069702 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0675955 |
| ASPH | aspartate beta-hydroxylase | 0.0674479 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0630538 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0626866 |
| TMSB10 | thymosin beta 10 | 0.0594937 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.058114 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0579232 |
| ACTN4 | actinin, alpha 4 | 0.055794 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0530058 |
| AEBP2 | AE binding protein 2 | 0.0515489 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.050845 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0505081 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0498848 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0494882 |
| PLEC | plectin | 0.0488925 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.048328 |
| SMAD3 | SMAD family member 3 | 0.0481728 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0471426 |
| MYO1E | myosin IE | 0.047015 |
| CCDC138 | coiled-coil domain containing 138 | 0.0459925 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0457087 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0456171 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0455615 |
| KRT86 | keratin 86, type II | 0.0454779 |
| ZNF644 | zinc finger protein 644 | 0.0452444 |
| ACTN1 | actinin, alpha 1 | 0.0448505 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0445133 |
| FLNA | filamin A, alpha | 0.0442252 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.044206 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0440067 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0438128 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0437637 |
| SCFD1 | sec1 family domain containing 1 | 0.0429853 |
| RPL11 | ribosomal protein L11 | 0.0429745 |
| CTBP2 | C-terminal binding protein 2 | 0.0427644 |
| LAMC2 | laminin, gamma 2 | 0.0419311 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.041289 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0402276 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0401265 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0396291 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.039464 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0384534 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0383811 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0383238 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0374144 |
| MYO1D | myosin ID | 0.0373125 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.037121 |
| SETX | senataxin | 0.0370443 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0362837 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0362045 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.0356537 |
| VMP1 | vacuole membrane protein 1 | 0.0353794 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0352766 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0350297 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0350193 |
| GOLGB1 | golgin B1 | 0.0349616 |
| RPL35 | ribosomal protein L35 | 0.0348877 |
| FUS | FUS RNA binding protein | 0.0347437 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0344066 |
| ECT2 | epithelial cell transforming 2 | 0.0341677 |
| ATXN1 | ataxin 1 | 0.0335035 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0330019 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0316541 |
| CLTC | clathrin, heavy chain (Hc) | 0.0316092 |
| SGMS2 | sphingomyelin synthase 2 | 0.031555 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0315427 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0314401 |
| FLNB | filamin B, beta | 0.0314206 |
| ANXA11 | annexin A11 | 0.0313635 |
| ANKRD17 | ankyrin repeat domain 17 | 0.031221 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0311793 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0311498 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0309677 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0309098 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0307191 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0306572 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0305571 |
| FNIP1 | folliculin interacting protein 1 | 0.0304766 |
| RPS4X | ribosomal protein S4, X-linked | 0.030286 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0302472 |
| RPL9 | ribosomal protein L9 | 0.0299371 |
| AFDN | afadin, adherens junction formation factor | 0.0294775 |
| COG6 | component of oligomeric golgi complex 6 | 0.0292397 |
| DPP4 | dipeptidyl-peptidase 4 | 0.028814 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0286711 |
| RCOR1 | REST corepressor 1 | 0.0286711 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.028129 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0280439 |
| ERBIN | erbb2 interacting protein | 0.0280382 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0279767 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0279179 |
| MED13 | mediator complex subunit 13 | 0.0278986 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0278831 |
| CDK13 | cyclin-dependent kinase 13 | 0.0277401 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.147431 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.124622 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.086051 |
| PKM | pyruvate kinase, muscle | -0.0730157 |
| PGK1 | phosphoglycerate kinase 1 | -0.0708962 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0633759 |
| ZNF292 | zinc finger protein 292 | -0.0609327 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.059179 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0581471 |
| ENO1 | enolase 1, (alpha) | -0.057324 |
| LDHA | lactate dehydrogenase A | -0.0553136 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0537788 |
| SEPTIN7 | septin 7 | -0.0528762 |
| AHNAK | AHNAK nucleoprotein | -0.0511442 |
| ANXA2 | annexin A2 | -0.0488729 |
| H1-0 | H1.0 linker histone | -0.0486774 |
| WDR45B | WD repeat domain 45B | -0.047543 |
| RLF | rearranged L-myc fusion | -0.0466314 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.046237 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0455879 |
| B2M | beta-2-microglobulin | -0.04527 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0437379 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.042907 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0414885 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0410032 |
| RPL35A | ribosomal protein L35a | -0.039865 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0393387 |
| RNF145 | ring finger protein 145 | -0.0387657 |
| SETD5 | SET domain containing 5 | -0.0385073 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0375528 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0375376 |
| TXNRD1 | thioredoxin reductase 1 | -0.0372144 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0370009 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0350551 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0346666 |
| HELZ | helicase with zinc finger | -0.0345188 |
| TMSB4X | thymosin beta 4, X-linked | -0.0342837 |
| KRT7 | keratin 7, type II | -0.0341947 |
| CCND1 | cyclin D1 | -0.0339862 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0338947 |
| GNAS | GNAS complex locus | -0.0335619 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0332378 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0330189 |
| CD44 | CD44 molecule (Indian blood group) | -0.0329928 |
| PHIP | pleckstrin homology domain interacting protein | -0.0319257 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0315864 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0315829 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0315298 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0303576 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0293433 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0293411 |
| TPD52 | tumor protein D52 | -0.0291615 |
| MATR3 | matrin 3 | -0.0290362 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0289682 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0287162 |
| RAD51B | RAD51 paralog B | -0.0286867 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0286495 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0285143 |
| VDAC1 | voltage-dependent anion channel 1 | -0.028307 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0280735 |
| EREG | epiregulin | -0.0274904 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0274466 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0272257 |
| UPP1 | uridine phosphorylase 1 | -0.0271866 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0270263 |
| POU5F1 | POU class 5 homeobox 1 | -0.0269551 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0269003 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0267218 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0267078 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0265746 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0265144 |
| INSIG2 | insulin induced gene 2 | -0.0264395 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.026422 |
| MAP4 | microtubule-associated protein 4 | -0.0264208 |
| ZFHX3 | zinc finger homeobox 3 | -0.0260192 |
| HMGA1 | high mobility group AT-hook 1 | -0.0258371 |
| PDGFC | platelet derived growth factor C | -0.0255607 |
| POTEF | POTE ankyrin domain family, member F | -0.0254269 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0253634 |
| KIF5B | kinesin family member 5B | -0.0248091 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0247351 |
| KPNB1 | karyopherin (importin) beta 1 | -0.024678 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0244274 |
| FBXO42 | F-box protein 42 | -0.0238654 |
| TUBB | tubulin, beta class I | -0.023817 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0235344 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0231975 |
| NDRG1 | N-myc downstream regulated 1 | -0.0231744 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0230724 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0230204 |
| URI1 | URI1, prefoldin-like chaperone | -0.0229976 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0227597 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0227172 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0225775 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0225217 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.022518 |
| SFXN1 | sideroflexin 1 | -0.0224662 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0222034 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | -0.022129 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0220837 |
