| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.167836 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.155909 |
| PLEC | plectin | 0.129566 |
| HMGA2 | high mobility group AT-hook 2 | 0.128191 |
| EXT1 | exostosin glycosyltransferase 1 | 0.114128 |
| DST | dystonin | 0.111975 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.111429 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0942782 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0903711 |
| SEPTIN9 | septin 9 | 0.0899888 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0851087 |
| AHNAK | AHNAK nucleoprotein | 0.0843042 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0784331 |
| COL5A1 | collagen, type V, alpha 1 | 0.0781761 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0771052 |
| MYO10 | myosin X | 0.0734919 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0731498 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0720686 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0703322 |
| SMYD3 | SET and MYND domain containing 3 | 0.0694957 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0690618 |
| CLIC4 | chloride intracellular channel 4 | 0.0683205 |
| ACTG1 | actin gamma 1 | 0.0675626 |
| TMSB10 | thymosin beta 10 | 0.0663998 |
| FLNA | filamin A, alpha | 0.0655486 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0653887 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0653841 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.063278 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0591327 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0570719 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0568958 |
| PRKCA | protein kinase C, alpha | 0.0567476 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0551702 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0547631 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0545679 |
| IGF1R | insulin-like growth factor 1 receptor | 0.053473 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0534519 |
| VCL | vinculin | 0.0512879 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0511107 |
| GRAMD1B | GRAM domain containing 1B | 0.0502952 |
| PRELID2 | PRELI domain containing 2 | 0.0500583 |
| INTS6 | integrator complex subunit 6 | 0.0497767 |
| NAV1 | neuron navigator 1 | 0.0496293 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0495639 |
| MSN | moesin | 0.0475949 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0474568 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0457159 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0451772 |
| ACTN4 | actinin, alpha 4 | 0.0449489 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.044423 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0430136 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0429128 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0425699 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0425446 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0421668 |
| INHBA | inhibin, beta A | 0.0418973 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0418076 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0412174 |
| TNS1 | tensin 1 | 0.040939 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0408369 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0408317 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.040615 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0405017 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0400394 |
| JMJD1C | jumonji domain containing 1C | 0.0397359 |
| LOXL2 | lysyl oxidase-like 2 | 0.0395996 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0389547 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0386907 |
| RRBP1 | ribosome binding protein 1 | 0.0386563 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0386266 |
| RCOR1 | REST corepressor 1 | 0.0383506 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0380413 |
| H1-4 | H1.4 linker histone, cluster member | 0.0379496 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0375293 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0372788 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.037163 |
| ACTN1 | actinin, alpha 1 | 0.0370948 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0365639 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0364136 |
| RPL3 | ribosomal protein L3 | 0.0361814 |
| H1-2 | H1.2 linker histone, cluster member | 0.0351556 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0350235 |
| RAI14 | retinoic acid induced 14 | 0.0345221 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0344175 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0341866 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0340886 |
| CEP112 | centrosomal protein 112kDa | 0.0340468 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0339495 |
| KLF12 | Kruppel-like factor 12 | 0.0335838 |
| WWOX | WW domain containing oxidoreductase | 0.0333041 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0332718 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0329446 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0322416 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0321254 |
| DNMBP | dynamin binding protein | 0.0321048 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0320857 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0319024 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.031662 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0315017 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0314382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.214861 |
| VIM | vimentin | -0.13813 |
| NDRG1 | N-myc downstream regulated 1 | -0.10431 |
| CDCP1 | CUB domain containing protein 1 | -0.100663 |
| MT2A | metallothionein 2A | -0.0701094 |
| FTL | ferritin, light polypeptide | -0.0652818 |
| IGF2 | insulin-like growth factor 2 | -0.0650774 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0619234 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0587226 |
| IL1B | interleukin 1, beta | -0.0551874 |
| EGR1 | early growth response 1 | -0.0511056 |
| NGLY1 | N-glycanase 1 | -0.0483154 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0461662 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0457523 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0455856 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0432706 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0411707 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0410334 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0397516 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0373262 |
| FAM13A | family with sequence similarity 13, member A | -0.0368141 |
| IER3 | immediate early response 3 | -0.034738 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0331465 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0325641 |
| TPM4 | tropomyosin 4 | -0.0324903 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0311357 |
| FOSL1 | FOS-like antigen 1 | -0.0310271 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0306431 |
| RPL35A | ribosomal protein L35a | -0.0305247 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0282786 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0280142 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0278855 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.0277622 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0276776 |
| RPS19 | ribosomal protein S19 | -0.0275943 |
| B2M | beta-2-microglobulin | -0.0275006 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0274737 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0267845 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0260782 |
| SEPTIN7 | septin 7 | -0.0257414 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0250728 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.024906 |
| PGK1 | phosphoglycerate kinase 1 | -0.0246911 |
| AXL | AXL receptor tyrosine kinase | -0.0246396 |
| VEGFA | vascular endothelial growth factor A | -0.0245563 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0241749 |
| SP3 | Sp3 transcription factor | -0.0240514 |
| LOX | lysyl oxidase | -0.02351 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0228415 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0227938 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0225837 |
| WDR45B | WD repeat domain 45B | -0.0225317 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0221509 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0217877 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0214247 |
| RPS23 | ribosomal protein S23 | -0.0213685 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0209898 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0209121 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0206972 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0204837 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0201067 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0199144 |
| RPS13 | ribosomal protein S13 | -0.0198938 |
| RPS20 | ribosomal protein S20 | -0.0198294 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0198081 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0197017 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0196616 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0192618 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0192268 |
| PTMA | prothymosin, alpha | -0.0191366 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0188567 |
| IKBIP | IKBKB interacting protein | -0.0188488 |
| RBM25 | RNA binding motif protein 25 | -0.0187311 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0184282 |
| SGO2 | shugoshin 2 | -0.0184272 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.018388 |
| FN1 | fibronectin 1 | -0.0182697 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0181975 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0181059 |
| RPLP1 | ribosomal protein, large, P1 | -0.0179076 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0178841 |
| STC1 | stanniocalcin 1 | -0.0178414 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0176216 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0175742 |
| TMEM165 | transmembrane protein 165 | -0.0175725 |
| HMGA1 | high mobility group AT-hook 1 | -0.0175339 |
| RPL36 | ribosomal protein L36 | -0.0173336 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0173104 |
| CD47 | CD47 molecule | -0.0170535 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.01684 |
| TMEM51 | transmembrane protein 51 | -0.0168102 |
| PRR11 | proline rich 11 | -0.0167153 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0165095 |
| MEF2A | myocyte enhancer factor 2A | -0.01647 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0163216 |
| ARF4 | ADP-ribosylation factor 4 | -0.0161848 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0160965 |
| AMPD3 | adenosine monophosphate deaminase 3 | -0.0160319 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0158898 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0157056 |
