| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.299565 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.216505 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.164043 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.150901 |
| PLEC | plectin | 0.143058 |
| NDRG1 | N-myc downstream regulated 1 | 0.130246 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.10462 |
| AHNAK | AHNAK nucleoprotein | 0.0824877 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0736429 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0726068 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0719536 |
| COL1A1 | collagen, type I, alpha 1 | 0.0717479 |
| CDH13 | cadherin 13 | 0.0695503 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0625161 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0608923 |
| FNDC3B | fibronectin type III domain containing 3B | 0.060105 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0570101 |
| CALR | calreticulin | 0.0535801 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0523939 |
| FMNL2 | formin-like 2 | 0.0506925 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0504498 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0492016 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0484907 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0481851 |
| CADM1 | cell adhesion molecule 1 | 0.0481133 |
| TMSB10 | thymosin beta 10 | 0.0470429 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0465202 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0463436 |
| SPAG9 | sperm associated antigen 9 | 0.0461787 |
| APP | amyloid beta (A4) precursor protein | 0.0453296 |
| DST | dystonin | 0.044476 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0443242 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0441629 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0426756 |
| NAV2 | neuron navigator 2 | 0.042122 |
| PDE10A | phosphodiesterase 10A | 0.0412467 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0400545 |
| CCNY | cyclin Y | 0.0392672 |
| SQSTM1 | sequestosome 1 | 0.0387335 |
| SP100 | SP100 nuclear antigen | 0.0386585 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0386435 |
| ASPH | aspartate beta-hydroxylase | 0.0385417 |
| HYOU1 | hypoxia up-regulated 1 | 0.0382863 |
| RRBP1 | ribosome binding protein 1 | 0.0378048 |
| ACTG1 | actin gamma 1 | 0.0371908 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0371868 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0359698 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0353801 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0349201 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0346351 |
| HLA-B | major histocompatibility complex, class I, B | 0.0346038 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0344491 |
| IER3 | immediate early response 3 | 0.0337704 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0333737 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0333322 |
| CAVIN1 | caveolae associated protein 1 | 0.0330132 |
| FLNA | filamin A, alpha | 0.0329635 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0329264 |
| SDC2 | syndecan 2 | 0.0323443 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0322488 |
| PTK2 | protein tyrosine kinase 2 | 0.0322132 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0318782 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0317154 |
| CTBP2 | C-terminal binding protein 2 | 0.0307943 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0306449 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0305506 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0302519 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0302363 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0301178 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0295058 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.029405 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.029391 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0293343 |
| RPL3 | ribosomal protein L3 | 0.0292595 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0291182 |
| TMSB4X | thymosin beta 4, X-linked | 0.0291034 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.028946 |
| OGA | O-GlcNAcase | 0.0288128 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0286232 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0284197 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0282559 |
| SFTPA2 | surfactant protein A2 | 0.0280929 |
| LOXL2 | lysyl oxidase-like 2 | 0.0277422 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0276506 |
| PTMA | prothymosin, alpha | 0.0276201 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.027557 |
| DENND5A | DENN/MADD domain containing 5A | 0.0275421 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0270184 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0269711 |
| HDLBP | high density lipoprotein binding protein | 0.0267553 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0267352 |
| RBM39 | RNA binding motif protein 39 | 0.0266447 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0265079 |
| GOLGA3 | golgin A3 | 0.0263472 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0261548 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0261187 |
| QKI | QKI, KH domain containing, RNA binding | 0.0261038 |
| MTDH | metadherin | 0.0260788 |
| MAP4 | microtubule-associated protein 4 | 0.0254243 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0250235 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.420126 |
| MT2A | metallothionein 2A | -0.117301 |
| FN1 | fibronectin 1 | -0.107533 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.097466 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0786524 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0730138 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.068768 |
| VCAN | versican | -0.0656895 |
| TPM4 | tropomyosin 4 | -0.062764 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.059858 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0587234 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0492476 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0480971 |
| COL1A2 | collagen, type I, alpha 2 | -0.0470788 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0379341 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0367386 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0320734 |
| EGR1 | early growth response 1 | -0.0309732 |
| IL6 | interleukin 6 | -0.0309143 |
| NRP1 | neuropilin 1 | -0.029989 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0292274 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0277967 |
| POSTN | periostin, osteoblast specific factor | -0.0277606 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0255475 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0248106 |
| AXL | AXL receptor tyrosine kinase | -0.0246124 |
| FOSL1 | FOS-like antigen 1 | -0.0237064 |
| TAPBP | TAP binding protein (tapasin) | -0.0232458 |
| ARRDC3 | arrestin domain containing 3 | -0.0221923 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0217889 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0216524 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0216285 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0212858 |
| SBF2 | SET binding factor 2 | -0.0211515 |
| MT1X | metallothionein 1X | -0.0205276 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0201327 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0198001 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0188844 |
| HMGA1 | high mobility group AT-hook 1 | -0.0186475 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0179845 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0177148 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0176853 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0174103 |
| OXR1 | oxidation resistance 1 | -0.0173219 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0172435 |
| LOX | lysyl oxidase | -0.0160921 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0160916 |
| RARB | retinoic acid receptor, beta | -0.016039 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0151987 |
| LIMA1 | LIM domain and actin binding 1 | -0.0151355 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0149536 |
| POTEF | POTE ankyrin domain family, member F | -0.0149 |
| PFN1 | profilin 1 | -0.014586 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0144113 |
| EGFR | epidermal growth factor receptor | -0.0143047 |
| MYADM | myeloid-associated differentiation marker | -0.0140116 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.013995 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0137444 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0134573 |
| TPM1 | tropomyosin 1 (alpha) | -0.0134464 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0132563 |
| BNC2 | basonuclin 2 | -0.0129756 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0129439 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0129012 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0127016 |
| SRGN | serglycin | -0.0126663 |
| ITGA11 | integrin, alpha 11 | -0.0123148 |
| HAS2 | hyaluronan synthase 2 | -0.0122989 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0122738 |
| SULF1 | sulfatase 1 | -0.0122301 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0121639 |
| EPHB1 | EPH receptor B1 | -0.012028 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0118619 |
| PKM | pyruvate kinase, muscle | -0.0118117 |
| OSMR | oncostatin M receptor | -0.0117163 |
| THBS1 | thrombospondin 1 | -0.0116969 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0116581 |
| MTSS1 | metastasis suppressor 1 | -0.0116183 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.011523 |
| RPS19 | ribosomal protein S19 | -0.0115229 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.0113054 |
| TENM3 | teneurin transmembrane protein 3 | -0.0112554 |
| TRIQK | triple QxxK/R motif containing | -0.0111115 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0110844 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0110129 |
| NREP | neuronal regeneration related protein | -0.0109516 |
| CPNE3 | copine III | -0.0108724 |
| IER2 | immediate early response 2 | -0.0108616 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0108398 |
| YBX1 | Y box binding protein 1 | -0.010752 |
| TMEM178B | transmembrane protein 178B | -0.0106313 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0105653 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0104051 |
| MLF1 | myeloid leukemia factor 1 | -0.0104003 |
| CFAP96 | cilia and flagella associated protein 96 | -0.0103373 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0101773 |
| PLAG1 | pleiomorphic adenoma gene 1 | -0.0101632 |
| PLBD2 | phospholipase B domain containing 2 | -0.0101261 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0100981 |
| ITGAV | integrin, alpha V | -0.0100934 |
