| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.224274 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.135845 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.115569 |
| APOA2 | apolipoprotein A-II | 0.104045 |
| TMSB10 | thymosin beta 10 | 0.0998161 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0932827 |
| RPL11 | ribosomal protein L11 | 0.0807337 |
| MT2A | metallothionein 2A | 0.0761524 |
| RPS21 | ribosomal protein S21 | 0.0664935 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0640584 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0629745 |
| RPS24 | ribosomal protein S24 | 0.0605577 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0593228 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0590014 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0559845 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0557173 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0554455 |
| RPL35A | ribosomal protein L35a | 0.0551531 |
| RPL26 | ribosomal protein L26 | 0.0548229 |
| SDC4 | syndecan 4 | 0.054709 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0530477 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.052817 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0520779 |
| SVIL | supervillin | 0.0509582 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0506207 |
| ATXN1 | ataxin 1 | 0.0497642 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0496105 |
| RPL34 | ribosomal protein L34 | 0.0492667 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0491491 |
| RPL37A | ribosomal protein L37a | 0.0467206 |
| RPS8 | ribosomal protein S8 | 0.0466989 |
| RPL12 | ribosomal protein L12 | 0.0456448 |
| RPS27A | ribosomal protein S27a | 0.0454326 |
| RPL23 | ribosomal protein L23 | 0.0450697 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0444567 |
| RPS6 | ribosomal protein S6 | 0.0443143 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0434182 |
| RPS19 | ribosomal protein S19 | 0.0428677 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.042753 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0421437 |
| FAM107B | family with sequence similarity 107, member B | 0.0406875 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0406446 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0400823 |
| RPLP2 | ribosomal protein, large, P2 | 0.039804 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0396629 |
| RPLP1 | ribosomal protein, large, P1 | 0.0394973 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0393672 |
| CCNY | cyclin Y | 0.0392672 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0389791 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0383617 |
| RPLP0 | ribosomal protein, large, P0 | 0.0383406 |
| HDLBP | high density lipoprotein binding protein | 0.0382813 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0381993 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0381349 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0380933 |
| RPS12 | ribosomal protein S12 | 0.0377464 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0376527 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0373901 |
| HMGA1 | high mobility group AT-hook 1 | 0.0370318 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0370171 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0366747 |
| CANX | calnexin | 0.0360046 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0352513 |
| KIF21A | kinesin family member 21A | 0.0350758 |
| RPL9 | ribosomal protein L9 | 0.0350172 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0347692 |
| GNAS | GNAS complex locus | 0.0347241 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0342805 |
| RAB1A | RAB1A, member RAS oncogene family | 0.034215 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0340213 |
| FMNL2 | formin-like 2 | 0.0334641 |
| KRT8 | keratin 8, type II | 0.032765 |
| PDE8A | phosphodiesterase 8A | 0.0323389 |
| H1-0 | H1.0 linker histone | 0.0320515 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0319171 |
| JAK1 | Janus kinase 1 | 0.0316896 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0315643 |
| PLEC | plectin | 0.0313761 |
| SMAD3 | SMAD family member 3 | 0.0313478 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0311202 |
| FOXP1 | forkhead box P1 | 0.0307304 |
| CLIC4 | chloride intracellular channel 4 | 0.0306992 |
| DTNA | dystrobrevin, alpha | 0.0306598 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0306563 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0304188 |
| AFDN | afadin, adherens junction formation factor | 0.030367 |
| AAK1 | AP2 associated kinase 1 | 0.0303371 |
| RBM39 | RNA binding motif protein 39 | 0.0303269 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0297104 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0294531 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0292956 |
| RPL31 | ribosomal protein L31 | 0.0287597 |
| RPL5 | ribosomal protein L5 | 0.0285822 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0283646 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0283336 |
| S100A9 | S100 calcium binding protein A9 | 0.0281184 |
| TOP1 | topoisomerase (DNA) I | 0.0280405 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0277815 |
| RPS17 | ribosomal protein S17 | 0.0277811 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0277444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.413104 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.12761 |
| C3 | complement component 3 | -0.11196 |
| DSPP | dentin sialophosphoprotein | -0.106731 |
| GPC6 | glypican 6 | -0.100509 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0995387 |
| APOB | apolipoprotein B | -0.0855708 |
| DST | dystonin | -0.0811446 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0768042 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0565979 |
| ITGAV | integrin, alpha V | -0.042708 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0411115 |
| FN1 | fibronectin 1 | -0.040818 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0385733 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0349185 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0345178 |
| EHBP1 | EH domain binding protein 1 | -0.0326637 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0300857 |
| A2M | alpha-2-macroglobulin | -0.0295086 |
| MALT1 | MALT1 paracaspase | -0.029211 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0288198 |
| FAT1 | FAT atypical cadherin 1 | -0.0283008 |
| TPM4 | tropomyosin 4 | -0.0282735 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0281225 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.027787 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0272997 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0264586 |
| RAI14 | retinoic acid induced 14 | -0.0258559 |
| ENAH | enabled homolog (Drosophila) | -0.0257097 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0255919 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0241007 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0239639 |
| VMP1 | vacuole membrane protein 1 | -0.0233886 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0233255 |
| KRT23 | keratin 23, type I | -0.0227595 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0226109 |
| RUNX1 | runt-related transcription factor 1 | -0.0225612 |
| TMEM123 | transmembrane protein 123 | -0.0223137 |
| JMJD1C | jumonji domain containing 1C | -0.0216557 |
| ZNF638 | zinc finger protein 638 | -0.0214128 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.021383 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0206668 |
| PEG3 | paternally expressed 3 | -0.0204009 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0202965 |
| MPZL2 | myelin protein zero-like 2 | -0.0200713 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0199028 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0198651 |
| OSMR | oncostatin M receptor | -0.0198543 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0197939 |
| TF | transferrin | -0.0197743 |
| VEGFA | vascular endothelial growth factor A | -0.0197073 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | -0.0194343 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.019331 |
| STK17A | serine/threonine kinase 17a | -0.0192849 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0190807 |
| ITGA1 | integrin, alpha 1 | -0.0189379 |
| FILIP1L | filamin A interacting protein 1-like | -0.0187371 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.018658 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0186139 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0185351 |
| ANGPTL2 | angiopoietin-like 2 | -0.0181834 |
| GK | glycerol kinase | -0.0181448 |
| CFB | complement factor B | -0.018027 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0178541 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0176998 |
| ARHGAP9 | Rho GTPase activating protein 9 | -0.0175884 |
| TPM3 | tropomyosin 3 | -0.01712 |
| TCIM | transcriptional and immune response regulator | -0.0170263 |
| ARFGEF3 | ARFGEF family member 3 | -0.0169985 |
| EPAS1 | endothelial PAS domain protein 1 | -0.016816 |
| RASAL2 | RAS protein activator like 2 | -0.0167551 |
| FKTN | fukutin | -0.0167375 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0167267 |
| RELL1 | RELT-like 1 | -0.0164671 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.016205 |
| CCN2 | cellular communication network factor 2 | -0.0161906 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.016176 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0160513 |
| PLSCR1 | phospholipid scramblase 1 | -0.016035 |
| DOK6 | docking protein 6 | -0.0159755 |
| TRIM26 | tripartite motif containing 26 | -0.0158645 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0156938 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0156056 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0154403 |
| RASA2 | RAS p21 protein activator 2 | -0.0154036 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0153118 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0152411 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.014842 |
| MATN3 | matrilin 3 | -0.0148183 |
| TGOLN2 | trans-golgi network protein 2 | -0.0147698 |
| PKD1L2 | polycystic kidney disease 1-like 2 (gene/pseudogene) | -0.0145808 |
| CCDC146 | coiled-coil domain containing 146 | -0.0144688 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.014464 |
| VCAN | versican | -0.0143015 |
| NHSL1 | NHS-like 1 | -0.014228 |
| SKIL | SKI-like proto-oncogene | -0.0141902 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0141852 |
| RAD51B | RAD51 paralog B | -0.0139018 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0138653 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0138397 |
