| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.169768 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.161858 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0950356 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0909081 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0853664 |
| TLE4 | transducin-like enhancer of split 4 | 0.0835857 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0807517 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0774198 |
| CALD1 | caldesmon 1 | 0.0743486 |
| INTS6 | integrator complex subunit 6 | 0.0730831 |
| RAB7A | RAB7A, member RAS oncogene family | 0.070197 |
| VCL | vinculin | 0.0696781 |
| MSN | moesin | 0.0673817 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0628427 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0613681 |
| ERBIN | erbb2 interacting protein | 0.0605086 |
| MAP1B | microtubule-associated protein 1B | 0.0571708 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0559825 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0559213 |
| HLA-B | major histocompatibility complex, class I, B | 0.0552439 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.055029 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0525944 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0518907 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0492614 |
| MT1X | metallothionein 1X | 0.0485905 |
| CLIC4 | chloride intracellular channel 4 | 0.0452208 |
| POTEF | POTE ankyrin domain family, member F | 0.0450813 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0422101 |
| ACTN1 | actinin, alpha 1 | 0.0415845 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0393988 |
| DSCAM | Down syndrome cell adhesion molecule | 0.039367 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.03919 |
| FNIP1 | folliculin interacting protein 1 | 0.0385071 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0383372 |
| ACTG1 | actin gamma 1 | 0.0382562 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0378997 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0378155 |
| FLNA | filamin A, alpha | 0.0366792 |
| RPS6 | ribosomal protein S6 | 0.0365412 |
| UBAP2 | ubiquitin associated protein 2 | 0.0362968 |
| SEPTIN9 | septin 9 | 0.0359756 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0358758 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0354608 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0354373 |
| NABP1 | nucleic acid binding protein 1 | 0.0352092 |
| NAV2 | neuron navigator 2 | 0.0351839 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0346909 |
| ATXN1 | ataxin 1 | 0.0344712 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0342502 |
| GOLGB1 | golgin B1 | 0.0338824 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0336934 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.033633 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0332348 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0331945 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0328801 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0327166 |
| BRD2 | bromodomain containing 2 | 0.0327135 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0322841 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0318827 |
| ZNF644 | zinc finger protein 644 | 0.031525 |
| CCNL1 | cyclin L1 | 0.0313487 |
| CREBBP | CREB binding protein | 0.0311756 |
| PMM2 | phosphomannomutase 2 | 0.0311601 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0309327 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0305875 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0304309 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0303906 |
| MYO1E | myosin IE | 0.0302556 |
| JMJD1C | jumonji domain containing 1C | 0.0300964 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0297057 |
| PFN1 | profilin 1 | 0.029474 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0291924 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0291362 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0289306 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0285488 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0285166 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0285105 |
| HDAC9 | histone deacetylase 9 | 0.028374 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0283189 |
| RND3 | Rho family GTPase 3 | 0.0282638 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0282454 |
| TOX4 | TOX high mobility group box family member 4 | 0.0281579 |
| TPM3 | tropomyosin 3 | 0.0281094 |
| SQSTM1 | sequestosome 1 | 0.0277514 |
| ASPH | aspartate beta-hydroxylase | 0.0277216 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0272573 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0269064 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0268865 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0266608 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0265746 |
| HMGA1 | high mobility group AT-hook 1 | 0.0264824 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0263743 |
| ADIPOR2 | adiponectin receptor 2 | 0.026021 |
| IL6ST | interleukin 6 signal transducer | 0.025953 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0257264 |
| RSU1 | Ras suppressor protein 1 | 0.0256871 |
| KLF12 | Kruppel-like factor 12 | 0.0255739 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0255259 |
| TMSB10 | thymosin beta 10 | 0.0254661 |
| TUFT1 | tuftelin 1 | 0.0254054 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.249397 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.158145 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.157572 |
| SLC12A8 | solute carrier family 12, member 8 | -0.100198 |
| ANXA2 | annexin A2 | -0.0897867 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0886238 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0783095 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0777358 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0742435 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.070044 |
| PPME1 | protein phosphatase methylesterase 1 | -0.061166 |
| PLCB4 | phospholipase C, beta 4 | -0.0597653 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0560783 |
| COL5A1 | collagen, type V, alpha 1 | -0.0558741 |
| AHNAK | AHNAK nucleoprotein | -0.0536658 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0525424 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0511156 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0489106 |
| TPD52 | tumor protein D52 | -0.0459645 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0448086 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0447692 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0439945 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0432404 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0423296 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0417042 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0394523 |
| CAVIN1 | caveolae associated protein 1 | -0.0386758 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0384432 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.038123 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0375643 |
| AFAP1 | actin filament associated protein 1 | -0.0375012 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0370377 |
| GLIS3 | GLIS family zinc finger 3 | -0.0369959 |
| PTMA | prothymosin, alpha | -0.03644 |
| LOX | lysyl oxidase | -0.0363258 |
| RLF | rearranged L-myc fusion | -0.0354597 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0353842 |
| SULF1 | sulfatase 1 | -0.0348837 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0347186 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.034678 |
| CANX | calnexin | -0.034001 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0335608 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0333533 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0328136 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0317984 |
| OSMR | oncostatin M receptor | -0.0314793 |
| GNAS | GNAS complex locus | -0.0313106 |
| ZFR | zinc finger RNA binding protein | -0.0311485 |
| HLA-C | major histocompatibility complex, class I, C | -0.0302504 |
| SEPTIN7 | septin 7 | -0.0293687 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0292846 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0290832 |
| ZNF841 | zinc finger protein 841 | -0.0290251 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0287525 |
| CEP170 | centrosomal protein 170kDa | -0.0285168 |
| MMP12 | matrix metallopeptidase 12 | -0.028445 |
| PGK1 | phosphoglycerate kinase 1 | -0.0281612 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0279826 |
| ANKRD10 | ankyrin repeat domain 10 | -0.027821 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0271736 |
| FSTL1 | follistatin-like 1 | -0.0267641 |
| SBF2 | SET binding factor 2 | -0.0266541 |
| LDHA | lactate dehydrogenase A | -0.0265532 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0264212 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0261894 |
| PDE10A | phosphodiesterase 10A | -0.0258048 |
| POSTN | periostin, osteoblast specific factor | -0.0255666 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0253894 |
| USP3 | ubiquitin specific peptidase 3 | -0.0253684 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0245103 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.024434 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0242799 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0242609 |
| PTK2 | protein tyrosine kinase 2 | -0.0240373 |
| FAM162A | family with sequence similarity 162, member A | -0.0234802 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0233777 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0228628 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0226831 |
| MPZL1 | myelin protein zero-like 1 | -0.0226781 |
| PHF20 | PHD finger protein 20 | -0.0225012 |
| WWC1 | WW and C2 domain containing 1 | -0.0224138 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0222402 |
| WDR45B | WD repeat domain 45B | -0.0221986 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0217591 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0213681 |
| GMPS | guanine monphosphate synthase | -0.0211464 |
| OXR1 | oxidation resistance 1 | -0.0209426 |
| ZNF432 | zinc finger protein 432 | -0.0208301 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0207991 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0207686 |
| TEX10 | testis expressed 10 | -0.0203047 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0202074 |
| INSIG2 | insulin induced gene 2 | -0.0200035 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0199398 |
| DENND4C | DENN/MADD domain containing 4C | -0.0199278 |
| ITGA1 | integrin, alpha 1 | -0.0198521 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.0198394 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0198271 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0196917 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.0195963 |
