| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.187663 |
| EXT1 | exostosin glycosyltransferase 1 | 0.15698 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.151321 |
| RPS6 | ribosomal protein S6 | 0.115726 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.105876 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0918988 |
| HDAC9 | histone deacetylase 9 | 0.0889438 |
| ASPH | aspartate beta-hydroxylase | 0.0884534 |
| EFNA5 | ephrin-A5 | 0.0879605 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0815423 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0807584 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0796511 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0780724 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.075432 |
| INTS6 | integrator complex subunit 6 | 0.0754021 |
| MYO10 | myosin X | 0.0742192 |
| NABP1 | nucleic acid binding protein 1 | 0.0727236 |
| TMSB10 | thymosin beta 10 | 0.0657018 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0636654 |
| RPS3 | ribosomal protein S3 | 0.0625639 |
| EGR1 | early growth response 1 | 0.0615888 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.061525 |
| TLE4 | transducin-like enhancer of split 4 | 0.0602581 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0594678 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.055444 |
| RUNX1 | runt-related transcription factor 1 | 0.0545294 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0544836 |
| RPL23 | ribosomal protein L23 | 0.0505409 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0500375 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0487965 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0486841 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.048582 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0485246 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0483026 |
| RPS12 | ribosomal protein S12 | 0.0467711 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0463799 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0461867 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0455024 |
| DOCK4 | dedicator of cytokinesis 4 | 0.042423 |
| AEBP2 | AE binding protein 2 | 0.0413634 |
| RTN4 | reticulon 4 | 0.0403443 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0403347 |
| JMJD1C | jumonji domain containing 1C | 0.0402171 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0399958 |
| H1-4 | H1.4 linker histone, cluster member | 0.0396359 |
| ACTG1 | actin gamma 1 | 0.039457 |
| RPS21 | ribosomal protein S21 | 0.0393393 |
| CORO1C | coronin, actin binding protein, 1C | 0.0383757 |
| FLNA | filamin A, alpha | 0.0380174 |
| PLEC | plectin | 0.0379608 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.037877 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.037603 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0372811 |
| RPL37A | ribosomal protein L37a | 0.0369548 |
| RPL4 | ribosomal protein L4 | 0.0368182 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0367311 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0364648 |
| TXNIP | thioredoxin interacting protein | 0.0363164 |
| RPLP0 | ribosomal protein, large, P0 | 0.0363144 |
| PRKCE | protein kinase C, epsilon | 0.0361134 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0349682 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0349476 |
| HMGA2 | high mobility group AT-hook 2 | 0.0347422 |
| JUN | jun proto-oncogene | 0.0345594 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0342201 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0341478 |
| CALD1 | caldesmon 1 | 0.0333108 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0329264 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0326338 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0325477 |
| USP34 | ubiquitin specific peptidase 34 | 0.0323132 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0321776 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0319983 |
| RPL12 | ribosomal protein L12 | 0.0317551 |
| RPS17 | ribosomal protein S17 | 0.0317095 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0316978 |
| RPLP2 | ribosomal protein, large, P2 | 0.0315876 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.031509 |
| MSN | moesin | 0.0314731 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0312189 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0311792 |
| ATF3 | activating transcription factor 3 | 0.0310447 |
| CD163L1 | CD163 molecule-like 1 | 0.030663 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0304582 |
| RPS23 | ribosomal protein S23 | 0.0304548 |
| RPS4X | ribosomal protein S4, X-linked | 0.0301347 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0301301 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0301141 |
| RPL26 | ribosomal protein L26 | 0.0300996 |
| NAV3 | neuron navigator 3 | 0.0300775 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0300697 |
| RPL7A | ribosomal protein L7a | 0.0298337 |
| MCL1 | myeloid cell leukemia 1 | 0.0294474 |
| RPL11 | ribosomal protein L11 | 0.0292102 |
| FUS | FUS RNA binding protein | 0.0291544 |
| RPS19 | ribosomal protein S19 | 0.0287015 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0286349 |
| KLHL29 | kelch-like family member 29 | 0.0285485 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0282649 |
| BRD2 | bromodomain containing 2 | 0.0279803 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP12 | matrix metallopeptidase 12 | -0.140056 |
| CD109 | CD109 molecule | -0.0850234 |
| VIM | vimentin | -0.070975 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0671733 |
| TPM4 | tropomyosin 4 | -0.0647425 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0605173 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0557283 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0548845 |
| FN1 | fibronectin 1 | -0.0547187 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0544969 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0534446 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0532807 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.051467 |
| PTK2 | protein tyrosine kinase 2 | -0.0514347 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0512871 |
| ANXA2 | annexin A2 | -0.0473247 |
| FNDC3B | fibronectin type III domain containing 3B | -0.045763 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0455799 |
| ZNF292 | zinc finger protein 292 | -0.0443625 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0440386 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0422896 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0420454 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0412116 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0409545 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0401165 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0388041 |
| CDK17 | cyclin-dependent kinase 17 | -0.0385661 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0384765 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0382662 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0379901 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0373587 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0362757 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0359241 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0356543 |
| RAI14 | retinoic acid induced 14 | -0.0347633 |
| PKM | pyruvate kinase, muscle | -0.0343314 |
| NRP2 | neuropilin 2 | -0.034268 |
| CTSB | cathepsin B | -0.0340448 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0339732 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0331862 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.033144 |
| RIGI | RNA sensor RIG-I | -0.0322205 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0309914 |
| BDNF | brain-derived neurotrophic factor | -0.0308902 |
| VCL | vinculin | -0.0299852 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0297372 |
| WDR45B | WD repeat domain 45B | -0.0293785 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0288097 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0287188 |
| VCAN | versican | -0.0286323 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0282536 |
| AHNAK | AHNAK nucleoprotein | -0.0282178 |
| SEPTIN7 | septin 7 | -0.0279903 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0278239 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0277315 |
| TMEM123 | transmembrane protein 123 | -0.0276302 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0274476 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0272304 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0270473 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0269676 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0265388 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0260295 |
| PGK1 | phosphoglycerate kinase 1 | -0.0260261 |
| NTM | neurotrimin | -0.0256168 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0255495 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0254312 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0253634 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0252641 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.025133 |
| TXNRD1 | thioredoxin reductase 1 | -0.0243088 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0242935 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0242269 |
| CLIC4 | chloride intracellular channel 4 | -0.0241812 |
| RNF145 | ring finger protein 145 | -0.0241271 |
| WWC1 | WW and C2 domain containing 1 | -0.0240516 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0239783 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0239446 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0235384 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0234024 |
| KYNU | kynureninase | -0.0233953 |
| ATP13A3 | ATPase type 13A3 | -0.0233261 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0232852 |
| LDHA | lactate dehydrogenase A | -0.0232382 |
| RFX7 | regulatory factor X, 7 | -0.0230446 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0230335 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0229945 |
| NUP58 | nucleoporin 58 | -0.0228434 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0228124 |
| TMEM200A | transmembrane protein 200A | -0.0226685 |
| CEP170 | centrosomal protein 170kDa | -0.0226453 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.02262 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0223433 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.022235 |
| TMEM41B | transmembrane protein 41B | -0.022215 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0219335 |
| GLMN | glomulin, FKBP associated protein | -0.021868 |
| SMAD3 | SMAD family member 3 | -0.0215629 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0212501 |
| USP3 | ubiquitin specific peptidase 3 | -0.0211886 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0210855 |
