| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | 0.12622 |
| MYO1E | myosin IE | 0.118335 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0869341 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0746779 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.071448 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.067495 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0636703 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0621927 |
| CADPS | Ca++-dependent secretion activator | 0.0603174 |
| VCL | vinculin | 0.0598804 |
| FAT1 | FAT atypical cadherin 1 | 0.0573393 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0553123 |
| ACTG1 | actin gamma 1 | 0.0544113 |
| ONECUT3 | one cut homeobox 3 | 0.0539954 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0524807 |
| TMSB10 | thymosin beta 10 | 0.0503195 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0488384 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0476214 |
| CUX1 | cut-like homeobox 1 | 0.0441121 |
| SMYD3 | SET and MYND domain containing 3 | 0.0416184 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0413008 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0402768 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0388752 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0388673 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0386863 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0381041 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0380056 |
| KRT18 | keratin 18, type I | 0.0375385 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0368542 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0362152 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0358448 |
| FHIT | fragile histidine triad | 0.0358077 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0355239 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0348214 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0346654 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0343869 |
| RAD51B | RAD51 paralog B | 0.0337099 |
| H1-4 | H1.4 linker histone, cluster member | 0.0321423 |
| RPS2 | ribosomal protein S2 | 0.0318948 |
| RPS21 | ribosomal protein S21 | 0.0314623 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0313119 |
| RPS12 | ribosomal protein S12 | 0.0308553 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0307322 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0303605 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303288 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0300032 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0299211 |
| RPL3 | ribosomal protein L3 | 0.0289675 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0286385 |
| RAB10 | RAB10, member RAS oncogene family | 0.0284229 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0283312 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.028279 |
| CD44 | CD44 molecule (Indian blood group) | 0.0280311 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0279097 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0274872 |
| SEPTIN9 | septin 9 | 0.027372 |
| AEBP2 | AE binding protein 2 | 0.0270821 |
| MYO5B | myosin VB | 0.0270471 |
| SVIL | supervillin | 0.0269541 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0269117 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0266681 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0266413 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0260353 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0258014 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0257488 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0257356 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0257147 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0255933 |
| DIAPH2 | diaphanous-related formin 2 | 0.0253996 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0249848 |
| FRMD5 | FERM domain containing 5 | 0.0249712 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0245908 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0244312 |
| NRXN3 | neurexin 3 | 0.0243241 |
| RPS6 | ribosomal protein S6 | 0.0243143 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0241424 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0240377 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0235936 |
| CTBP2 | C-terminal binding protein 2 | 0.0235816 |
| ASPH | aspartate beta-hydroxylase | 0.0235325 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0234158 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0233498 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0233482 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0232582 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0232278 |
| CNKSR3 | CNKSR family member 3 | 0.0230254 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.022801 |
| NEBL | nebulette | 0.0223903 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0223103 |
| LMO7 | LIM domain 7 | 0.0219506 |
| SH3D19 | SH3 domain containing 19 | 0.021926 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0218543 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0218507 |
| RPL26 | ribosomal protein L26 | 0.0217929 |
| EXOC4 | exocyst complex component 4 | 0.0217561 |
| MECOM | MDS1 and EVI1 complex locus | 0.0217542 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0215706 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0213248 |
| PDZD8 | PDZ domain containing 8 | 0.0211468 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0210924 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.223889 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.179379 |
| ANXA2 | annexin A2 | -0.127139 |
| EZR | ezrin | -0.119141 |
| PTMA | prothymosin, alpha | -0.110854 |
| NDRG1 | N-myc downstream regulated 1 | -0.101749 |
| FAM13A | family with sequence similarity 13, member A | -0.0910077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0861473 |
| ITGA6 | integrin, alpha 6 | -0.0833105 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0797019 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0791224 |
| TNS4 | tensin 4 | -0.0780986 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0776285 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0763763 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0753571 |
| TXNIP | thioredoxin interacting protein | -0.0748615 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0710776 |
| ENO1 | enolase 1, (alpha) | -0.0653995 |
| LDHA | lactate dehydrogenase A | -0.0633508 |
| FLNB | filamin B, beta | -0.0630956 |
| WDR45B | WD repeat domain 45B | -0.0630817 |
| FNBP1L | formin binding protein 1-like | -0.0620952 |
| PGK1 | phosphoglycerate kinase 1 | -0.0611196 |
| AHNAK | AHNAK nucleoprotein | -0.0575804 |
| TPM4 | tropomyosin 4 | -0.0569552 |
| GOLGA4 | golgin A4 | -0.0559664 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.055813 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0557419 |
| KIF5B | kinesin family member 5B | -0.0534847 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0484079 |
| CANX | calnexin | -0.0482199 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0480493 |
| RNF43 | ring finger protein 43 | -0.0476306 |
| EPCAM | epithelial cell adhesion molecule | -0.0450951 |
| EREG | epiregulin | -0.0442143 |
| RBM39 | RNA binding motif protein 39 | -0.0441862 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0440703 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0435844 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.043559 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0434815 |
| ZNF292 | zinc finger protein 292 | -0.043357 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0433329 |
| UBC | ubiquitin C | -0.0424006 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0422324 |
| CCNY | cyclin Y | -0.0421862 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0419353 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0419179 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0415658 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0404389 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0402942 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0395405 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0388671 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0387721 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0384395 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0383161 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0377359 |
| OGA | O-GlcNAcase | -0.0372456 |
| ITGB4 | integrin, beta 4 | -0.0369963 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0368649 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0363619 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.035934 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0359174 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0356602 |
| USP3 | ubiquitin specific peptidase 3 | -0.0353219 |
| EXOC1 | exocyst complex component 1 | -0.0348557 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0346908 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0341918 |
| INSIG1 | insulin induced gene 1 | -0.034059 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0338497 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0333898 |
| RNF145 | ring finger protein 145 | -0.0331408 |
| PKM | pyruvate kinase, muscle | -0.0328935 |
| RLF | rearranged L-myc fusion | -0.0323806 |
| TPD52 | tumor protein D52 | -0.0323121 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0320455 |
| MED13L | mediator complex subunit 13-like | -0.0320259 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0318532 |
| RREB1 | ras responsive element binding protein 1 | -0.0312574 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0312392 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0312198 |
| AGR2 | anterior gradient 2 | -0.0311084 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0310271 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0309776 |
| CALB1 | calbindin 1, 28kDa | -0.0308544 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0308075 |
| FERMT1 | fermitin family member 1 | -0.030595 |
| EHF | ets homologous factor | -0.0303988 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0302913 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0301073 |
| TES | testin LIM domain protein | -0.0300591 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0300429 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0300139 |
| RTN4 | reticulon 4 | -0.0298945 |
| GDF15 | growth differentiation factor 15 | -0.0296215 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0295289 |
| EPHA2 | EPH receptor A2 | -0.0294911 |
| SHROOM3 | shroom family member 3 | -0.0293177 |
| PERP | PERP, TP53 apoptosis effector | -0.0284547 |
| FHL2 | four and a half LIM domains 2 | -0.0283213 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0282579 |
