| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0935577 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0679881 |
| RPL4 | ribosomal protein L4 | 0.0629698 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0626434 |
| CTBP2 | C-terminal binding protein 2 | 0.0625664 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0618698 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0618196 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0601813 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.059206 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0575745 |
| PLEC | plectin | 0.0558773 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0542445 |
| RPL3 | ribosomal protein L3 | 0.0539788 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0520761 |
| TMSB10 | thymosin beta 10 | 0.0504898 |
| LMO7 | LIM domain 7 | 0.0490187 |
| RNF145 | ring finger protein 145 | 0.0468649 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0466914 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0463277 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0456987 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0453446 |
| KRT18 | keratin 18, type I | 0.0453442 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0427137 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0417217 |
| HDLBP | high density lipoprotein binding protein | 0.040633 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.040035 |
| PTMA | prothymosin, alpha | 0.0398718 |
| ASPH | aspartate beta-hydroxylase | 0.0383661 |
| GOLGA3 | golgin A3 | 0.0375523 |
| RPL19 | ribosomal protein L19 | 0.0367502 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364282 |
| RPLP1 | ribosomal protein, large, P1 | 0.0361393 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0360104 |
| RPLP2 | ribosomal protein, large, P2 | 0.0331829 |
| RRBP1 | ribosome binding protein 1 | 0.0328643 |
| RPS21 | ribosomal protein S21 | 0.0327874 |
| RPS27A | ribosomal protein S27a | 0.0323983 |
| RPS3 | ribosomal protein S3 | 0.0317006 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0316867 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0310504 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0307054 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0306655 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0306354 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0304547 |
| OGA | O-GlcNAcase | 0.030127 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0297247 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0295778 |
| RPL14 | ribosomal protein L14 | 0.0290781 |
| RNF43 | ring finger protein 43 | 0.0287969 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0287319 |
| PDZD8 | PDZ domain containing 8 | 0.028629 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0285966 |
| FUS | FUS RNA binding protein | 0.0284557 |
| RPS19 | ribosomal protein S19 | 0.028427 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.028309 |
| RPL35 | ribosomal protein L35 | 0.0282973 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0282259 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0278952 |
| MYO1E | myosin IE | 0.0277564 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0273668 |
| AHNAK | AHNAK nucleoprotein | 0.0270903 |
| FAT1 | FAT atypical cadherin 1 | 0.0268321 |
| RPL41 | ribosomal protein L41 | 0.0266237 |
| RPL7A | ribosomal protein L7a | 0.0261714 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0261467 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0261136 |
| FOXO1 | forkhead box O1 | 0.025529 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0250888 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0250703 |
| RREB1 | ras responsive element binding protein 1 | 0.0250211 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.024546 |
| CCND2 | cyclin D2 | 0.0241991 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0240819 |
| HYOU1 | hypoxia up-regulated 1 | 0.023934 |
| RPL6 | ribosomal protein L6 | 0.023648 |
| MSI2 | musashi RNA-binding protein 2 | 0.0236037 |
| RPL8 | ribosomal protein L8 | 0.0235859 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0232989 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0231959 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0231465 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.02292 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0229107 |
| RPS15A | ribosomal protein S15a | 0.02269 |
| KRT8 | keratin 8, type II | 0.0224772 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0223304 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0221882 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.0220872 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0220726 |
| TOP1 | topoisomerase (DNA) I | 0.0218025 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0217339 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | 0.021723 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0217154 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0216227 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.021269 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0212046 |
| RPL18 | ribosomal protein L18 | 0.0205899 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0205401 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0205133 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0203691 |
| KLC1 | kinesin light chain 1 | 0.0203463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.2037 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.132488 |
| CALB1 | calbindin 1, 28kDa | -0.126419 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.120487 |
| ANXA2 | annexin A2 | -0.103052 |
| VCL | vinculin | -0.0960684 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0744609 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0744364 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0733064 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0696878 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.068293 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0663233 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.064457 |
| LAMA4 | laminin, alpha 4 | -0.0622916 |
| RIGI | RNA sensor RIG-I | -0.0598534 |
| MX1 | MX dynamin-like GTPase 1 | -0.0577281 |
| PLSCR1 | phospholipid scramblase 1 | -0.0569231 |
| CLDN4 | claudin 4 | -0.0558547 |
| DSG3 | desmoglein 3 | -0.0502286 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0494667 |
| POTEF | POTE ankyrin domain family, member F | -0.0491623 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0486662 |
| MYOF | myoferlin | -0.0474763 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0470108 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0453951 |
| TRIM2 | tripartite motif containing 2 | -0.0451471 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0449346 |
| PRSS3 | protease, serine, 3 | -0.0444972 |
| ETNK1 | ethanolamine kinase 1 | -0.0430354 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0422162 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0421712 |
| RAD51B | RAD51 paralog B | -0.0398005 |
| SP100 | SP100 nuclear antigen | -0.0392739 |
| EGR1 | early growth response 1 | -0.0391184 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.03869 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0380729 |
| FLNB | filamin B, beta | -0.0376514 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0375257 |
| TJP1 | tight junction protein 1 | -0.0373118 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0360817 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0353557 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0353019 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0347609 |
| PERP | PERP, TP53 apoptosis effector | -0.0346281 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0343949 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.033994 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0332948 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0330686 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0326387 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0318018 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0312772 |
| RBM25 | RNA binding motif protein 25 | -0.031001 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0309388 |
| PLAC8 | placenta-specific 8 | -0.0300505 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0300447 |
| FOSL1 | FOS-like antigen 1 | -0.0294361 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0292952 |
| NPSR1 | neuropeptide S receptor 1 | -0.0291994 |
| HMGA1 | high mobility group AT-hook 1 | -0.0291732 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0290595 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0289799 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0288165 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0283636 |
| CAV2 | caveolin 2 | -0.0280704 |
| RPL35A | ribosomal protein L35a | -0.0280543 |
| ANXA3 | annexin A3 | -0.0279534 |
| JUP | junction plakoglobin | -0.0279324 |
| SH3D19 | SH3 domain containing 19 | -0.0278687 |
| ANXA11 | annexin A11 | -0.027769 |
| LAMB3 | laminin, beta 3 | -0.0277196 |
| LIMA1 | LIM domain and actin binding 1 | -0.0276693 |
| PCBP2 | poly(rC) binding protein 2 | -0.0275598 |
| COBL | cordon-bleu WH2 repeat protein | -0.027377 |
| RIN2 | Ras and Rab interactor 2 | -0.0272962 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0271889 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0270128 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.026937 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0268563 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0267902 |
| LDHA | lactate dehydrogenase A | -0.026561 |
| ITGA6 | integrin, alpha 6 | -0.0264604 |
| MCU | mitochondrial calcium uniporter | -0.0262875 |
| AOPEP | aminopeptidase O (putative) | -0.0255983 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0253647 |
| RCOR1 | REST corepressor 1 | -0.0252854 |
| MUC13 | mucin 13, cell surface associated | -0.0250751 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0249647 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.024941 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0248594 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0242458 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0239722 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0238346 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0236178 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0235956 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.023585 |
| MYO6 | myosin VI | -0.023507 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.0234972 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0234336 |
| ADIPOR2 | adiponectin receptor 2 | -0.0231044 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0230239 |
