| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.191625 |
| LMO7 | LIM domain 7 | 0.0959143 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0929448 |
| GRAMD1B | GRAM domain containing 1B | 0.0917875 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0814939 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0787849 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0763135 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0762907 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0742305 |
| SLTM | SAFB-like, transcription modulator | 0.0728405 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0609933 |
| SPAG9 | sperm associated antigen 9 | 0.0608546 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0603643 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0597 |
| TES | testin LIM domain protein | 0.0565874 |
| NABP1 | nucleic acid binding protein 1 | 0.056151 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0560079 |
| HOMER1 | homer scaffolding protein 1 | 0.0536398 |
| TOP1 | topoisomerase (DNA) I | 0.0531841 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0526581 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0522254 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0519427 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0515992 |
| EGR1 | early growth response 1 | 0.0511561 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0497428 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0491584 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0480848 |
| SIK3 | SIK family kinase 3 | 0.0479467 |
| HYOU1 | hypoxia up-regulated 1 | 0.0475393 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0473106 |
| AREG | amphiregulin | 0.046736 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0465817 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0455697 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0454639 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0452127 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.044854 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0448305 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0440226 |
| SCEL | sciellin | 0.0429908 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0418809 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0414876 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0397829 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0396761 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0395059 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0386698 |
| MYO1E | myosin IE | 0.0381444 |
| INTS6 | integrator complex subunit 6 | 0.0371618 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0370846 |
| MYOF | myoferlin | 0.0369374 |
| MYO5B | myosin VB | 0.0368791 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0368076 |
| TJP1 | tight junction protein 1 | 0.0363311 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0358569 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0356343 |
| SYAP1 | synapse associated protein 1 | 0.0347819 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0345408 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0342362 |
| SON | SON DNA binding protein | 0.0340754 |
| PLEC | plectin | 0.0338182 |
| KRT18 | keratin 18, type I | 0.0332904 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0330094 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0328352 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0324758 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0323718 |
| SMYD3 | SET and MYND domain containing 3 | 0.0316874 |
| MORF4L2 | mortality factor 4 like 2 | 0.031497 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0312843 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0311799 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.031175 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0311491 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0306055 |
| SVIL | supervillin | 0.0304631 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0297039 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0296599 |
| MT2A | metallothionein 2A | 0.0289949 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0281975 |
| BMP6 | bone morphogenetic protein 6 | 0.0281732 |
| SGMS2 | sphingomyelin synthase 2 | 0.0281215 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0280243 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0278117 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0277346 |
| DST | dystonin | 0.0275817 |
| PYGL | phosphorylase, glycogen, liver | 0.0273169 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0268768 |
| IRS2 | insulin receptor substrate 2 | 0.0267424 |
| RPS3 | ribosomal protein S3 | 0.0264772 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0259389 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0259228 |
| OXSR1 | oxidative stress responsive 1 | 0.0255953 |
| SETX | senataxin | 0.0255458 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0253295 |
| MAP7 | microtubule-associated protein 7 | 0.025282 |
| BRD2 | bromodomain containing 2 | 0.0250934 |
| JMJD1C | jumonji domain containing 1C | 0.025071 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.024688 |
| USP53 | ubiquitin specific peptidase 53 | 0.0245405 |
| JUN | jun proto-oncogene | 0.0245181 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0243507 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.0243505 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0238588 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.403488 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.146211 |
| EGFR | epidermal growth factor receptor | -0.115673 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0993853 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0872054 |
| SMAD3 | SMAD family member 3 | -0.0867063 |
| FAM13A | family with sequence similarity 13, member A | -0.0746934 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0734593 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0703842 |
| EFNA5 | ephrin-A5 | -0.0702541 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0681541 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0661213 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0656867 |
| TXNRD1 | thioredoxin reductase 1 | -0.0623185 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0611753 |
| OSMR | oncostatin M receptor | -0.0591966 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0565632 |
| NDRG1 | N-myc downstream regulated 1 | -0.054257 |
| ANXA2 | annexin A2 | -0.0507842 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0506774 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0475123 |
| PKM | pyruvate kinase, muscle | -0.0424858 |
| CES1 | carboxylesterase 1 | -0.0407836 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0394003 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0387101 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0387042 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0377478 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0375386 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0374524 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0373169 |
| RIN2 | Ras and Rab interactor 2 | -0.0348603 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.034426 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.034171 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0325983 |
| TMEM45B | transmembrane protein 45B | -0.0322549 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0322032 |
| NGLY1 | N-glycanase 1 | -0.0314725 |
| TMEM165 | transmembrane protein 165 | -0.0310051 |
| RIGI | RNA sensor RIG-I | -0.0309899 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0308098 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0301298 |
| SLMAP | sarcolemma associated protein | -0.0296272 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0291637 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0291255 |
| TRIM56 | tripartite motif containing 56 | -0.02887 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0287132 |
| TNS3 | tensin 3 | -0.0283734 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0283094 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0274493 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0274425 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0273152 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0270375 |
| CDCP1 | CUB domain containing protein 1 | -0.0269358 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0267651 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0264915 |
| ARRDC3 | arrestin domain containing 3 | -0.0261866 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0260791 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0259408 |
| YEATS2 | YEATS domain containing 2 | -0.0252731 |
| LAMA4 | laminin, alpha 4 | -0.0250716 |
| LAMC2 | laminin, gamma 2 | -0.0249416 |
| ZNF292 | zinc finger protein 292 | -0.0245264 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0244164 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0242339 |
| PDE8A | phosphodiesterase 8A | -0.0241243 |
| RNF217 | ring finger protein 217 | -0.0238927 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0236775 |
| RNF149 | ring finger protein 149 | -0.0234556 |
| TPD52 | tumor protein D52 | -0.0229755 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0229339 |
| FNBP1L | formin binding protein 1-like | -0.022905 |
| PHF21A | PHD finger protein 21A | -0.0228662 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0228644 |
| CP | ceruloplasmin (ferroxidase) | -0.02284 |
| SBF2 | SET binding factor 2 | -0.0227703 |
| PTMA | prothymosin, alpha | -0.0221595 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0220776 |
| PGK1 | phosphoglycerate kinase 1 | -0.0217122 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.021624 |
| CAB39 | calcium binding protein 39 | -0.0215657 |
| GNAS | GNAS complex locus | -0.0206084 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0204363 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0202748 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0200654 |
| WDR45B | WD repeat domain 45B | -0.0200613 |
| RAI14 | retinoic acid induced 14 | -0.0199558 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0199039 |
| ZNF638 | zinc finger protein 638 | -0.0198731 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0198006 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0196528 |
| FRY | furry homolog (Drosophila) | -0.0196406 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0194056 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0191396 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0187885 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0186895 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0186892 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | -0.0186533 |
| ITSN2 | intersectin 2 | -0.0184622 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0182687 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -0.0182151 |
