| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.129367 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0998464 |
| FAM20C | family with sequence similarity 20, member C | 0.0861249 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0773457 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.075062 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0642222 |
| SMAD3 | SMAD family member 3 | 0.0617101 |
| CD44 | CD44 molecule (Indian blood group) | 0.0586077 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0562174 |
| GLCCI1 | glucocorticoid induced 1 | 0.0554265 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0506144 |
| MT2A | metallothionein 2A | 0.0505861 |
| NAV2 | neuron navigator 2 | 0.0488786 |
| INTS6 | integrator complex subunit 6 | 0.0485101 |
| NAV1 | neuron navigator 1 | 0.048502 |
| AADAC | arylacetamide deacetylase | 0.0463927 |
| MYO10 | myosin X | 0.0441802 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0430017 |
| PRELID2 | PRELI domain containing 2 | 0.0429201 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0428826 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0427732 |
| NTN4 | netrin 4 | 0.0425229 |
| HMGA2 | high mobility group AT-hook 2 | 0.0417891 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0404965 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0399333 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0392185 |
| RAD51B | RAD51 paralog B | 0.0391882 |
| SEPTIN9 | septin 9 | 0.0373842 |
| IFI44L | interferon-induced protein 44-like | 0.0369725 |
| SP100 | SP100 nuclear antigen | 0.0366234 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0362828 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0361804 |
| TGFB1 | transforming growth factor, beta 1 | 0.0358826 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0345412 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0340055 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0333028 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0330869 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0320147 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0317012 |
| DST | dystonin | 0.0316594 |
| HDAC4 | histone deacetylase 4 | 0.031571 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0309108 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0304852 |
| AHNAK | AHNAK nucleoprotein | 0.0303151 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0299459 |
| EGFR | epidermal growth factor receptor | 0.0294634 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0292805 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0289628 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0288958 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0284252 |
| KIAA1217 | KIAA1217 | 0.0281092 |
| LOXL2 | lysyl oxidase-like 2 | 0.027995 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0279583 |
| SVIL | supervillin | 0.0278894 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.027682 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0276198 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0273927 |
| RASAL2 | RAS protein activator like 2 | 0.0273601 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0273417 |
| CDH13 | cadherin 13 | 0.0267826 |
| EFNA5 | ephrin-A5 | 0.026291 |
| AVIL | advillin | 0.0261785 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0261204 |
| TNNC1 | troponin C type 1 (slow) | 0.0255197 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0252274 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0251277 |
| VCL | vinculin | 0.0250751 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.025067 |
| EXOC4 | exocyst complex component 4 | 0.0249264 |
| TGM2 | transglutaminase 2 | 0.0249218 |
| SMYD3 | SET and MYND domain containing 3 | 0.0246638 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0244992 |
| RPL11 | ribosomal protein L11 | 0.0244073 |
| NABP1 | nucleic acid binding protein 1 | 0.0242213 |
| RNF144A | ring finger protein 144A | 0.0241114 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0239921 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0239637 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0239262 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0235027 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0232434 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0231374 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0230495 |
| CTBP2 | C-terminal binding protein 2 | 0.0229354 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0228761 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0227221 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0220377 |
| GOLGA3 | golgin A3 | 0.0215458 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0213727 |
| SYT1 | synaptotagmin I | 0.0212868 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.02119 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0211737 |
| WLS | wntless Wnt ligand secretion mediator | 0.0210455 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0208261 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0206042 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0205395 |
| MICALL2 | MICAL-like 2 | 0.020452 |
| ECE1 | endothelin converting enzyme 1 | 0.0204248 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0201822 |
| MED13 | mediator complex subunit 13 | 0.0201619 |
| HDLBP | high density lipoprotein binding protein | 0.020047 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.182736 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.156147 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.137728 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.12377 |
| FN1 | fibronectin 1 | -0.0970987 |
| MEF2A | myocyte enhancer factor 2A | -0.0957017 |
| FAM13A | family with sequence similarity 13, member A | -0.0902281 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.090139 |
| GOLGA4 | golgin A4 | -0.0896219 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0809937 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.080915 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.07608 |
| USP34 | ubiquitin specific peptidase 34 | -0.0716565 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0624128 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0604543 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0604181 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0603624 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0600826 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.059841 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0595662 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0587116 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0571459 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0557457 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0531309 |
| RUNX2 | runt-related transcription factor 2 | -0.0523711 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0518325 |
| OSMR | oncostatin M receptor | -0.0517793 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0513725 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0511777 |
| PCBP2 | poly(rC) binding protein 2 | -0.0491777 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0490094 |
| RAI14 | retinoic acid induced 14 | -0.0465083 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0462616 |
| NGLY1 | N-glycanase 1 | -0.0462433 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0456634 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0450469 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0447159 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0436489 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0423064 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0420294 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0419922 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0412657 |
| ATP13A3 | ATPase type 13A3 | -0.0411515 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0408938 |
| ZNF292 | zinc finger protein 292 | -0.0403293 |
| OXSR1 | oxidative stress responsive 1 | -0.0399282 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0389215 |
| FTL | ferritin, light polypeptide | -0.0379828 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.037628 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.037431 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0373761 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.037204 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0370697 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0370528 |
| VIM | vimentin | -0.0368853 |
| ITGAV | integrin, alpha V | -0.0368204 |
| SEC24A | SEC24 family member A | -0.0366021 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.03572 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.03539 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0353212 |
| RIOK3 | RIO kinase 3 | -0.0351098 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.034843 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0348359 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.034531 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0341214 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0339191 |
| CDCP1 | CUB domain containing protein 1 | -0.0339077 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.033803 |
| USP3 | ubiquitin specific peptidase 3 | -0.0337745 |
| RBM39 | RNA binding motif protein 39 | -0.0333317 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0327241 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0326559 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0325288 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0324761 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.032319 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0322541 |
| TMEM165 | transmembrane protein 165 | -0.0318386 |
| MECOM | MDS1 and EVI1 complex locus | -0.0315921 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0314689 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0313299 |
| SETD5 | SET domain containing 5 | -0.0309643 |
| WDR45B | WD repeat domain 45B | -0.0308279 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0308217 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0306752 |
| DNER | delta/notch-like EGF repeat containing | -0.0306173 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0301463 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0299347 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0294071 |
| SPAG9 | sperm associated antigen 9 | -0.0293815 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0286673 |
| TSPAN5 | tetraspanin 5 | -0.0286177 |
| SRP54 | signal recognition particle 54kDa | -0.0283582 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0281963 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0279751 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0276456 |
| MTSS1 | metastasis suppressor 1 | -0.0275432 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0274832 |
| MAP1B | microtubule-associated protein 1B | -0.0273821 |
| SNX9 | sorting nexin 9 | -0.0273808 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0272814 |
