| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.14155 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.111085 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.103791 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0896535 |
| MCL1 | myeloid cell leukemia 1 | 0.0857898 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0767573 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0761278 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0704678 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0703122 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0670344 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0669566 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.064133 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0623468 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0610523 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0582548 |
| HOMER1 | homer scaffolding protein 1 | 0.0582228 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0575134 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0565684 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0565307 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0564228 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.056211 |
| INTS6 | integrator complex subunit 6 | 0.0557298 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0547338 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0536005 |
| YBX3 | Y box binding protein 3 | 0.0531617 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0517709 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0510316 |
| EXT1 | exostosin glycosyltransferase 1 | 0.050782 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0481142 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0477434 |
| KRT18 | keratin 18, type I | 0.0472787 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0472256 |
| TPI1 | triosephosphate isomerase 1 | 0.0471372 |
| SLC38A2 | solute carrier family 38, member 2 | 0.046462 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0461978 |
| RRM2 | ribonucleotide reductase M2 | 0.0456606 |
| BRD2 | bromodomain containing 2 | 0.0456293 |
| FUS | FUS RNA binding protein | 0.0451049 |
| JMJD1C | jumonji domain containing 1C | 0.0450877 |
| RAD51B | RAD51 paralog B | 0.0449316 |
| YAP1 | Yes-associated protein 1 | 0.0436466 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0429165 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0418765 |
| NABP1 | nucleic acid binding protein 1 | 0.0418471 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0417173 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0416588 |
| VCL | vinculin | 0.0413269 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0405112 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.04002 |
| CPNE1 | copine I | 0.0399412 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0391142 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0389524 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0388608 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0387469 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0385585 |
| SMYD3 | SET and MYND domain containing 3 | 0.0377774 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0375107 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0370205 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.036268 |
| RPS21 | ribosomal protein S21 | 0.0362133 |
| OSMR | oncostatin M receptor | 0.0357266 |
| STK4 | serine/threonine kinase 4 | 0.0356648 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0354427 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0350469 |
| CTTN | cortactin | 0.034887 |
| TXNRD1 | thioredoxin reductase 1 | 0.0347329 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0343873 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0342431 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.033885 |
| RCOR1 | REST corepressor 1 | 0.0336502 |
| FBXO11 | F-box protein 11 | 0.0334767 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0328994 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0327852 |
| ATP11A | ATPase, class VI, type 11A | 0.0322554 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0322297 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.032126 |
| CDK17 | cyclin-dependent kinase 17 | 0.031916 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0318621 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0317119 |
| RPL3 | ribosomal protein L3 | 0.0316572 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0316327 |
| TRIM59 | tripartite motif containing 59 | 0.0313003 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0312254 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0312049 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0311377 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0309551 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0303915 |
| CUL3 | cullin 3 | 0.0301888 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0298782 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0298751 |
| ATP13A3 | ATPase type 13A3 | 0.0298326 |
| PRKCE | protein kinase C, epsilon | 0.029782 |
| AEBP2 | AE binding protein 2 | 0.0294358 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0292474 |
| TPM2 | tropomyosin 2 (beta) | 0.0291614 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0291445 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0286688 |
| ACTG1 | actin gamma 1 | 0.0286383 |
| DST | dystonin | 0.0286207 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0284892 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.169664 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.153879 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.144539 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.136822 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0974843 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.095528 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.082683 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0814409 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0647168 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0625741 |
| VIM | vimentin | -0.0601166 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0592565 |
| RSF1 | remodeling and spacing factor 1 | -0.0589233 |
| ENO1 | enolase 1, (alpha) | -0.0534469 |
| PTMA | prothymosin, alpha | -0.051511 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0498487 |
| PHF21A | PHD finger protein 21A | -0.0489006 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0484047 |
| PDE10A | phosphodiesterase 10A | -0.0462373 |
| CANX | calnexin | -0.0460268 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0457155 |
| BBX | bobby sox homolog (Drosophila) | -0.0454045 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0453966 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0421134 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0410936 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0408173 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0399345 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0394131 |
| RPL35A | ribosomal protein L35a | -0.0389158 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0388801 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0387906 |
| TPM4 | tropomyosin 4 | -0.038052 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0379433 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0371648 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.035825 |
| WDR45B | WD repeat domain 45B | -0.035739 |
| SBF2 | SET binding factor 2 | -0.0355085 |
| ANXA2 | annexin A2 | -0.0346728 |
| EHBP1 | EH domain binding protein 1 | -0.0341913 |
| GOLGA4 | golgin A4 | -0.0340161 |
| PGK1 | phosphoglycerate kinase 1 | -0.0335594 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0325141 |
| FAM168A | family with sequence similarity 168, member A | -0.0324469 |
| MAP4 | microtubule-associated protein 4 | -0.0324088 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0321628 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0321173 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0319436 |
| VDAC1 | voltage-dependent anion channel 1 | -0.031709 |
| ZNF638 | zinc finger protein 638 | -0.0315521 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0313623 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0310201 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0306458 |
| WASF2 | WAS protein family, member 2 | -0.0306365 |
| FAM13A | family with sequence similarity 13, member A | -0.0305729 |
| POTEF | POTE ankyrin domain family, member F | -0.0304412 |
| ZNF292 | zinc finger protein 292 | -0.030137 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0301015 |
| DENND5B | DENN/MADD domain containing 5B | -0.0300993 |
| SMAD3 | SMAD family member 3 | -0.0299648 |
| SRP72 | signal recognition particle 72kDa | -0.0298864 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0298505 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0297527 |
| LDHA | lactate dehydrogenase A | -0.0297215 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0297198 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0290484 |
| SRP54 | signal recognition particle 54kDa | -0.0290411 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0289165 |
| PKM | pyruvate kinase, muscle | -0.0285175 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0283836 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0280784 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.028052 |
| CLDN1 | claudin 1 | -0.02801 |
| LATS2 | large tumor suppressor kinase 2 | -0.0279861 |
| RYR3 | ryanodine receptor 3 | -0.027839 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0277307 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0276125 |
| LDHB | lactate dehydrogenase B | -0.0275932 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0275592 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0274984 |
| FTL | ferritin, light polypeptide | -0.0273167 |
| CALR | calreticulin | -0.0270697 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.027027 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0269074 |
| COPA | coatomer protein complex, subunit alpha | -0.0266366 |
| IGF2 | insulin-like growth factor 2 | -0.0264607 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0264257 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0262722 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0258904 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.025852 |
| EGFR | epidermal growth factor receptor | -0.0257774 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0256574 |
| RNF213 | ring finger protein 213 | -0.025617 |
| RFX7 | regulatory factor X, 7 | -0.0255171 |
| HDGF | hepatoma-derived growth factor | -0.0254826 |
| HM13 | histocompatibility (minor) 13 | -0.0251926 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0251208 |
| GRAMD1B | GRAM domain containing 1B | -0.025083 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0248408 |
| PLAC8 | placenta-specific 8 | -0.0247798 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0247501 |
