| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.154123 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.154019 |
| EXT1 | exostosin glycosyltransferase 1 | 0.131641 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.116309 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.111538 |
| PLEC | plectin | 0.103055 |
| FTL | ferritin, light polypeptide | 0.097124 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0920052 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0888893 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0811372 |
| TMSB10 | thymosin beta 10 | 0.0757704 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0753877 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0749298 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0676531 |
| DSPP | dentin sialophosphoprotein | 0.0664305 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0663203 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0645442 |
| RNF213 | ring finger protein 213 | 0.0640359 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0627196 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0605075 |
| ERBIN | erbb2 interacting protein | 0.0594916 |
| MX1 | MX dynamin-like GTPase 1 | 0.0594727 |
| TJP1 | tight junction protein 1 | 0.0582481 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0570127 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.056978 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0569567 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0567036 |
| ETV6 | ets variant 6 | 0.0555505 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0544261 |
| AHNAK | AHNAK nucleoprotein | 0.0541433 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0536239 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0535173 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0529776 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0522769 |
| MSN | moesin | 0.0519479 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0516646 |
| FBXO32 | F-box protein 32 | 0.0511105 |
| SEPTIN11 | septin 11 | 0.0504884 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0504288 |
| KRT8 | keratin 8, type II | 0.0493212 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0489305 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0482009 |
| VGLL3 | vestigial-like family member 3 | 0.0473574 |
| OCLN | occludin | 0.0468867 |
| MYO5B | myosin VB | 0.0467283 |
| MX2 | MX dynamin-like GTPase 2 | 0.0454291 |
| DUSP10 | dual specificity phosphatase 10 | 0.044603 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0439231 |
| MYO1E | myosin IE | 0.0430641 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0430512 |
| UBC | ubiquitin C | 0.0429298 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0417744 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0412013 |
| MYO6 | myosin VI | 0.0411433 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0411043 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0409927 |
| RAB10 | RAB10, member RAS oncogene family | 0.0406911 |
| LMO7 | LIM domain 7 | 0.0398962 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0385244 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0381253 |
| PALLD | palladin, cytoskeletal associated protein | 0.0381214 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0380653 |
| MCU | mitochondrial calcium uniporter | 0.0380541 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0373558 |
| BRD2 | bromodomain containing 2 | 0.0369827 |
| PTMA | prothymosin, alpha | 0.0369354 |
| RPL3 | ribosomal protein L3 | 0.0366526 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0366176 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0366056 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0365237 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0364101 |
| SMAD3 | SMAD family member 3 | 0.0361422 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0360355 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0357845 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0350789 |
| GRAMD2B | GRAM domain containing 2B | 0.0349805 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0349663 |
| PRKCA | protein kinase C, alpha | 0.0349656 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0348552 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.034632 |
| RASAL2 | RAS protein activator like 2 | 0.0346028 |
| INTS6 | integrator complex subunit 6 | 0.0344163 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0342539 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0342371 |
| H1-0 | H1.0 linker histone | 0.0337762 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0334688 |
| SVIL | supervillin | 0.0332977 |
| FNIP1 | folliculin interacting protein 1 | 0.0331757 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0331648 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0329523 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0329008 |
| SEPTIN9 | septin 9 | 0.0328892 |
| SGMS2 | sphingomyelin synthase 2 | 0.032833 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0327296 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0326965 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.032557 |
| KRT7 | keratin 7, type II | 0.032433 |
| SP100 | SP100 nuclear antigen | 0.0323152 |
| FHIT | fragile histidine triad | 0.031889 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0318365 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.18021 |
| FN1 | fibronectin 1 | -0.126063 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.104733 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0793223 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0767203 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0736253 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0631731 |
| HMGA1 | high mobility group AT-hook 1 | -0.0594877 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0523027 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0512086 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0490416 |
| TFG | TRK-fused gene | -0.0479099 |
| RPL35A | ribosomal protein L35a | -0.0471327 |
| RBM39 | RNA binding motif protein 39 | -0.0458689 |
| ASPH | aspartate beta-hydroxylase | -0.0447465 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0437496 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0435366 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0424092 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0423261 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0412111 |
| RNF145 | ring finger protein 145 | -0.0378957 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0378702 |
| MATR3 | matrin 3 | -0.0372601 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0367688 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0366681 |
| PGK1 | phosphoglycerate kinase 1 | -0.0364802 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0358195 |
| TXNRD1 | thioredoxin reductase 1 | -0.035423 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0351004 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0350124 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0345802 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0334609 |
| RAD21 | RAD21 homolog (S. pombe) | -0.033287 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0331874 |
| CCND1 | cyclin D1 | -0.0318838 |
| FAM162A | family with sequence similarity 162, member A | -0.0314484 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0309843 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0308863 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0305341 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0303975 |
| RLF | rearranged L-myc fusion | -0.0302955 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0301998 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0300182 |
| SEPTIN7 | septin 7 | -0.0299393 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0296662 |
| ARRDC3 | arrestin domain containing 3 | -0.0296351 |
| CDCP1 | CUB domain containing protein 1 | -0.0293903 |
| USP3 | ubiquitin specific peptidase 3 | -0.0289645 |
| GNAS | GNAS complex locus | -0.028907 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0284835 |
| CHMP2B | charged multivesicular body protein 2B | -0.0284295 |
| AZIN1 | antizyme inhibitor 1 | -0.0283095 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0280099 |
| CCNL1 | cyclin L1 | -0.0278424 |
| RPLP1 | ribosomal protein, large, P1 | -0.0274283 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0274033 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0273131 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0258137 |
| S100A6 | S100 calcium binding protein A6 | -0.0255436 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0251785 |
| RTN4 | reticulon 4 | -0.0251683 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.024905 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0248353 |
| TMEM165 | transmembrane protein 165 | -0.0236397 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0231166 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0231034 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0230128 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0224789 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0223988 |
| ANXA2 | annexin A2 | -0.0223834 |
| TPM4 | tropomyosin 4 | -0.0222747 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0221803 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | -0.022014 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0219188 |
| PEG10 | paternally expressed 10 | -0.0217474 |
| FAM13A | family with sequence similarity 13, member A | -0.0214785 |
| UPP1 | uridine phosphorylase 1 | -0.0213958 |
| CANX | calnexin | -0.0213147 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0212064 |
| ANXA5 | annexin A5 | -0.0210823 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0208887 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0205416 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0205088 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0198655 |
| CDC73 | cell division cycle 73 | -0.0198367 |
| NUP54 | nucleoporin 54kDa | -0.0198137 |
| TFRC | transferrin receptor | -0.019651 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0196475 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0194874 |
| WDR43 | WD repeat domain 43 | -0.0194737 |
| SLMAP | sarcolemma associated protein | -0.0194347 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0191354 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0190249 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | -0.0189555 |
| OGA | O-GlcNAcase | -0.0188972 |
| KDM1A | lysine (K)-specific demethylase 1A | -0.0185126 |
| NGLY1 | N-glycanase 1 | -0.0184879 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | -0.01837 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0182093 |
| MORF4L1 | mortality factor 4 like 1 | -0.0179685 |
