| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.200862 |
| PDE10A | phosphodiesterase 10A | 0.135735 |
| DST | dystonin | 0.105154 |
| PM20D1 | peptidase M20 domain containing 1 | 0.100073 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0883172 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0792548 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0686419 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0666847 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0656241 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.064637 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0608926 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.057414 |
| SMAD2 | SMAD family member 2 | 0.0570526 |
| INTS6 | integrator complex subunit 6 | 0.0569242 |
| SMYD3 | SET and MYND domain containing 3 | 0.0524341 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0501089 |
| HDAC4 | histone deacetylase 4 | 0.0477936 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0470839 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0453465 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0452573 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0448969 |
| VCL | vinculin | 0.0438952 |
| FMNL2 | formin-like 2 | 0.0427488 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0410075 |
| RAD51B | RAD51 paralog B | 0.0409367 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0402771 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0396521 |
| KYNU | kynureninase | 0.0391736 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.038567 |
| PRELID2 | PRELI domain containing 2 | 0.0369093 |
| CTBP2 | C-terminal binding protein 2 | 0.0364765 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0362113 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0354327 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0350306 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0342024 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0340287 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.033744 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0337181 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0328568 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0328437 |
| MAP7 | microtubule-associated protein 7 | 0.0325755 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0315429 |
| KIAA0825 | KIAA0825 | 0.0308642 |
| AEBP2 | AE binding protein 2 | 0.0308467 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0295693 |
| COL5A2 | collagen, type V, alpha 2 | 0.0288456 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0287132 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0280485 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0273557 |
| SEPTIN9 | septin 9 | 0.0270934 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0251834 |
| CUX1 | cut-like homeobox 1 | 0.0246948 |
| EXOC4 | exocyst complex component 4 | 0.0246115 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.024467 |
| BMP6 | bone morphogenetic protein 6 | 0.0243827 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0242727 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0242225 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0238475 |
| FLNA | filamin A, alpha | 0.0238353 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0235914 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0227539 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0227403 |
| FOXK1 | forkhead box K1 | 0.022371 |
| DENND1A | DENN/MADD domain containing 1A | 0.0222395 |
| XYLT1 | xylosyltransferase I | 0.0221137 |
| GOLGA3 | golgin A3 | 0.0219438 |
| GPHN | gephyrin | 0.0219055 |
| ZNF644 | zinc finger protein 644 | 0.0218637 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0215182 |
| DNER | delta/notch-like EGF repeat containing | 0.0215153 |
| ATXN7 | ataxin 7 | 0.0213293 |
| CADM2 | cell adhesion molecule 2 | 0.0212356 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0212165 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0211335 |
| LSAMP | limbic system-associated membrane protein | 0.0207707 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0207042 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0206066 |
| AUTS2 | autism susceptibility candidate 2 | 0.0203576 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0202269 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0202052 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0202024 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0201159 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0201128 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0197188 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0196676 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0196457 |
| FUS | FUS RNA binding protein | 0.0195395 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0194382 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0194338 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0193234 |
| PRSS23 | protease, serine, 23 | 0.0191211 |
| PLEC | plectin | 0.0187682 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0187358 |
| TMSB10 | thymosin beta 10 | 0.0186558 |
| RASAL2 | RAS protein activator like 2 | 0.0184855 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.018442 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0182626 |
| PRKCA | protein kinase C, alpha | 0.0180651 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0180641 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0177841 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.224777 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.218312 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.199796 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.122309 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.108011 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0849347 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0816066 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0794184 |
| MYOF | myoferlin | -0.0754006 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0752646 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0670661 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0651143 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0626455 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0575194 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0572351 |
| VIM | vimentin | -0.0566745 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0558338 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0551318 |
| TXNRD1 | thioredoxin reductase 1 | -0.0537373 |
| PGK1 | phosphoglycerate kinase 1 | -0.0505637 |
| LDHA | lactate dehydrogenase A | -0.0486705 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0485219 |
| NRCAM | neuronal cell adhesion molecule | -0.0484449 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0481074 |
| ASPH | aspartate beta-hydroxylase | -0.0468567 |
| MCL1 | myeloid cell leukemia 1 | -0.0464415 |
| RTN4 | reticulon 4 | -0.0456673 |
| NDRG1 | N-myc downstream regulated 1 | -0.0450652 |
| FTL | ferritin, light polypeptide | -0.0430711 |
| STC1 | stanniocalcin 1 | -0.0429882 |
| MFF | mitochondrial fission factor | -0.0421913 |
| LAMB1 | laminin, beta 1 | -0.0421657 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0418478 |
| SPAG9 | sperm associated antigen 9 | -0.0417538 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0403976 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0398057 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0394805 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0394349 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.039323 |
| ZNF292 | zinc finger protein 292 | -0.0392374 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0392257 |
| PTMA | prothymosin, alpha | -0.0389265 |
| PTGR1 | prostaglandin reductase 1 | -0.0385457 |
| B2M | beta-2-microglobulin | -0.0382735 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0377897 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0376909 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0376421 |
| FAM13A | family with sequence similarity 13, member A | -0.0371438 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0370818 |
| EFNA5 | ephrin-A5 | -0.0367638 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0365225 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0363566 |
| WDR45B | WD repeat domain 45B | -0.0362713 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0358158 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0353409 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0349619 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0346816 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0345943 |
| CANX | calnexin | -0.0345192 |
| NEK7 | NIMA-related kinase 7 | -0.0343556 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0338438 |
| GOLGA4 | golgin A4 | -0.0328562 |
| NUP58 | nucleoporin 58 | -0.0325687 |
| CD109 | CD109 molecule | -0.0323089 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0308952 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0308481 |
| IL6 | interleukin 6 | -0.0307866 |
| HELZ | helicase with zinc finger | -0.0306755 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0304409 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0304146 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0300867 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0299303 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0296929 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0296475 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0296206 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0288859 |
| RAI1 | retinoic acid induced 1 | -0.0287693 |
| EGR1 | early growth response 1 | -0.0282486 |
| S100A10 | S100 calcium binding protein A10 | -0.027412 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0273592 |
| PYGL | phosphorylase, glycogen, liver | -0.0272562 |
| GDA | guanine deaminase | -0.0271196 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0270595 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0269241 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.026629 |
| TPR | translocated promoter region, nuclear basket protein | -0.0265849 |
| PCBP3 | poly(rC) binding protein 3 | -0.0265472 |
| TPD52 | tumor protein D52 | -0.0265203 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0264332 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0263182 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0259282 |
| UBC | ubiquitin C | -0.0258426 |
| ANXA5 | annexin A5 | -0.0258229 |
| USP3 | ubiquitin specific peptidase 3 | -0.0256472 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.025218 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0248847 |
| CCDC88A | coiled-coil domain containing 88A | -0.0247889 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0247315 |
| ANXA2 | annexin A2 | -0.0246954 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0246932 |
