| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.110377 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0841605 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0705347 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0669716 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0652799 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0593923 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0565789 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0557358 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0534094 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0516801 |
| USP53 | ubiquitin specific peptidase 53 | 0.0513033 |
| USP25 | ubiquitin specific peptidase 25 | 0.0488791 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0480129 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0470963 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0446069 |
| JMJD1C | jumonji domain containing 1C | 0.0429868 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0428881 |
| RPS8 | ribosomal protein S8 | 0.0421078 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.040786 |
| HMCN1 | hemicentin 1 | 0.0395862 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0395684 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0394424 |
| RPS13 | ribosomal protein S13 | 0.039363 |
| TENM3 | teneurin transmembrane protein 3 | 0.0389086 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0388137 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0387459 |
| ZNF217 | zinc finger protein 217 | 0.0387312 |
| RPL5 | ribosomal protein L5 | 0.0383986 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0383142 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0377542 |
| LPIN2 | lipin 2 | 0.0372288 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0369602 |
| TMSB10 | thymosin beta 10 | 0.0367252 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0364135 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0363255 |
| PHF21A | PHD finger protein 21A | 0.0362176 |
| ACTN4 | actinin, alpha 4 | 0.0360857 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0357587 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0356179 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0352739 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0349768 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0345184 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0338451 |
| RPS12 | ribosomal protein S12 | 0.0336977 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0336688 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0336517 |
| EVI5 | ecotropic viral integration site 5 | 0.0335156 |
| RPL23 | ribosomal protein L23 | 0.032918 |
| RPS21 | ribosomal protein S21 | 0.0328241 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0327795 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0327376 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0325764 |
| OLA1 | Obg-like ATPase 1 | 0.0323217 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.0321741 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0319933 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.031816 |
| TFRC | transferrin receptor | 0.0316041 |
| RPL19 | ribosomal protein L19 | 0.0310263 |
| AFAP1 | actin filament associated protein 1 | 0.0310109 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0307487 |
| RCOR1 | REST corepressor 1 | 0.0306665 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0305997 |
| SON | SON DNA binding protein | 0.0304405 |
| CDYL | chromodomain protein, Y-like | 0.0299627 |
| CADM2 | cell adhesion molecule 2 | 0.0295417 |
| SMYD3 | SET and MYND domain containing 3 | 0.0289813 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0288914 |
| CTBP2 | C-terminal binding protein 2 | 0.0285946 |
| COL3A1 | collagen, type III, alpha 1 | 0.0285595 |
| TRIM2 | tripartite motif containing 2 | 0.0285274 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0282257 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0280967 |
| COG5 | component of oligomeric golgi complex 5 | 0.0279064 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0276424 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0272588 |
| KIAA1328 | KIAA1328 | 0.0265634 |
| PDGFC | platelet derived growth factor C | 0.0265114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0263536 |
| SFTPA2 | surfactant protein A2 | 0.0259174 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0258383 |
| SKI | SKI proto-oncogene | 0.0254744 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0250829 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0248641 |
| ATF3 | activating transcription factor 3 | 0.0246703 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0246104 |
| SIK3 | SIK family kinase 3 | 0.02414 |
| KIAA1958 | KIAA1958 | 0.024107 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0239637 |
| GPC4 | glypican 4 | 0.0238085 |
| XPO6 | exportin 6 | 0.0237642 |
| RPL37 | ribosomal protein L37 | 0.0236468 |
| INTS6 | integrator complex subunit 6 | 0.02362 |
| RPL9 | ribosomal protein L9 | 0.023459 |
| HIP1 | huntingtin interacting protein 1 | 0.0234134 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0233746 |
| CEP350 | centrosomal protein 350kDa | 0.0233423 |
| FUS | FUS RNA binding protein | 0.0232942 |
| EPHA5 | EPH receptor A5 | 0.0231871 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0231114 |
| RPL3 | ribosomal protein L3 | 0.0230958 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | -0.136015 |
| PEG10 | paternally expressed 10 | -0.100814 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0854474 |
| GPC3 | glypican 3 | -0.0748241 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0716684 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0662525 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0619069 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0603755 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0552436 |
| RAI1 | retinoic acid induced 1 | -0.0550035 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0544788 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0542789 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0495782 |
| MAP4 | microtubule-associated protein 4 | -0.0471145 |
| CCN2 | cellular communication network factor 2 | -0.0457875 |
| SHROOM3 | shroom family member 3 | -0.0455475 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0453819 |
| PCDH9 | protocadherin 9 | -0.0431939 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0431814 |
| NRG1 | neuregulin 1 | -0.0414024 |
| EMP1 | epithelial membrane protein 1 | -0.0412765 |
| POTEF | POTE ankyrin domain family, member F | -0.0409292 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0408084 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0402021 |
| PFN1 | profilin 1 | -0.0399385 |
| METAP2 | methionyl aminopeptidase 2 | -0.0389733 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.038898 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0386343 |
| CENPE | centromere protein E, 312kDa | -0.0382224 |
| NPAS3 | neuronal PAS domain protein 3 | -0.036498 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0364562 |
| FN1 | fibronectin 1 | -0.0356888 |
| CDH19 | cadherin 19, type 2 | -0.0353449 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0351852 |
| NTM | neurotrimin | -0.0339427 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.031123 |
| CENPF | centromere protein F, 350/400kDa | -0.0309845 |
| FST | follistatin | -0.0308904 |
| PRR16 | proline rich 16 | -0.030331 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0298347 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0296732 |
| RTN4 | reticulon 4 | -0.0296585 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0289669 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0285101 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0284758 |
| LRRC4C | leucine rich repeat containing 4C | -0.0283726 |
| PRTG | protogenin | -0.0279214 |
| DIAPH3 | diaphanous-related formin 3 | -0.0278711 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0277483 |
| SMC3 | structural maintenance of chromosomes 3 | -0.027742 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0277223 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0273487 |
| HYOU1 | hypoxia up-regulated 1 | -0.0270507 |
| FBXO17 | F-box protein 17 | -0.0268242 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0266829 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0257093 |
| MITF | microphthalmia-associated transcription factor | -0.0255561 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0254097 |
| LDHA | lactate dehydrogenase A | -0.0251704 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0249456 |
| TMEM123 | transmembrane protein 123 | -0.0247343 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.0239176 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0238517 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0237505 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0235871 |
| TENM2 | teneurin transmembrane protein 2 | -0.0235854 |
| CFL2 | cofilin 2 (muscle) | -0.0234874 |
| MAPK9 | mitogen-activated protein kinase 9 | -0.023196 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.0231872 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0231563 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0231502 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | -0.0230246 |
| FBL | fibrillarin | -0.0230111 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0228745 |
| ZNF292 | zinc finger protein 292 | -0.0226567 |
| NLGN1 | neuroligin 1 | -0.0226461 |
| FAT1 | FAT atypical cadherin 1 | -0.0226055 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0225457 |
| MKI67 | marker of proliferation Ki-67 | -0.0224613 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0222794 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0222371 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0221619 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0221003 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0218972 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0215609 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0213678 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0212758 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0212413 |
| RBM25 | RNA binding motif protein 25 | -0.0212269 |
| TFG | TRK-fused gene | -0.0212058 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0211305 |
| GSK3B | glycogen synthase kinase 3 beta | -0.021064 |
| DENR | density-regulated protein | -0.0210366 |
| PRR11 | proline rich 11 | -0.0210175 |
| LUZP2 | leucine zipper protein 2 | -0.0207885 |
| DIPK1A | divergent protein kinase domain 1A | -0.0207686 |
| DPPA4 | developmental pluripotency associated 4 | -0.0207221 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0206395 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0206212 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0205288 |
