| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.331056 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.256849 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.160979 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.119665 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.112399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.102529 |
| SFTPA2 | surfactant protein A2 | 0.102286 |
| EGR1 | early growth response 1 | 0.0997282 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0828803 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0720057 |
| MCL1 | myeloid cell leukemia 1 | 0.0676928 |
| RPS12 | ribosomal protein S12 | 0.0667657 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.065099 |
| FBL | fibrillarin | 0.0619421 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0609036 |
| MSN | moesin | 0.0603066 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0598903 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0580045 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0557875 |
| CENPF | centromere protein F, 350/400kDa | 0.0557192 |
| PLEC | plectin | 0.0555146 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0547084 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0543762 |
| NUP98 | nucleoporin 98kDa | 0.0541614 |
| RPS3 | ribosomal protein S3 | 0.0537344 |
| RPL11 | ribosomal protein L11 | 0.0524677 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0513027 |
| INTS6 | integrator complex subunit 6 | 0.0476185 |
| ANGPTL4 | angiopoietin-like 4 | 0.0454085 |
| RPL3 | ribosomal protein L3 | 0.0450651 |
| BRD2 | bromodomain containing 2 | 0.0449719 |
| TPM3 | tropomyosin 3 | 0.0440601 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0438888 |
| MYO1E | myosin IE | 0.0434069 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0433882 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0432361 |
| SET | SET nuclear proto-oncogene | 0.042167 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0416897 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0406763 |
| HYOU1 | hypoxia up-regulated 1 | 0.0403876 |
| RPL4 | ribosomal protein L4 | 0.0402333 |
| RRM2 | ribonucleotide reductase M2 | 0.0400264 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0397313 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0397205 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.039615 |
| HDAC9 | histone deacetylase 9 | 0.0385057 |
| RPLP0 | ribosomal protein, large, P0 | 0.0378404 |
| RPS2 | ribosomal protein S2 | 0.0376469 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0376257 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0376233 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0376196 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0372543 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0368842 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0359216 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0357166 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0356593 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0348252 |
| MT2A | metallothionein 2A | 0.0347979 |
| JUN | jun proto-oncogene | 0.0346821 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0344329 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0342782 |
| ACTG1 | actin gamma 1 | 0.034118 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0335179 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0331299 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0331069 |
| MORF4L2 | mortality factor 4 like 2 | 0.0330469 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0325432 |
| NONO | non-POU domain containing, octamer-binding | 0.032537 |
| VEGFA | vascular endothelial growth factor A | 0.0323712 |
| RPS15A | ribosomal protein S15a | 0.0320335 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0319508 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0317441 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0316473 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0313232 |
| RPS27A | ribosomal protein S27a | 0.0312642 |
| FTL | ferritin, light polypeptide | 0.031252 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0308183 |
| RPLP2 | ribosomal protein, large, P2 | 0.0308168 |
| RACK1 | receptor for activated C kinase 1 | 0.0307882 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0307659 |
| CLTA | clathrin, light chain A | 0.0307426 |
| RPS17 | ribosomal protein S17 | 0.0302216 |
| UBC | ubiquitin C | 0.0298568 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0286032 |
| TPX2 | TPX2, microtubule-associated | 0.0285997 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0282344 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0281951 |
| TPM2 | tropomyosin 2 (beta) | 0.0280966 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0278618 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0277969 |
| SETX | senataxin | 0.0276693 |
| BMP6 | bone morphogenetic protein 6 | 0.0273344 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0273301 |
| SPAG9 | sperm associated antigen 9 | 0.0272437 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0271051 |
| CPNE1 | copine I | 0.0264732 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0263252 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0262749 |
| VMP1 | vacuole membrane protein 1 | 0.0261661 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0260971 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.210319 |
| AHNAK | AHNAK nucleoprotein | -0.129834 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.113279 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.107342 |
| ANXA2 | annexin A2 | -0.0912129 |
| AFAP1 | actin filament associated protein 1 | -0.0787065 |
| TMEM123 | transmembrane protein 123 | -0.0661571 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0629688 |
| MEF2A | myocyte enhancer factor 2A | -0.0623857 |
| ZNF780B | zinc finger protein 780B | -0.0529749 |
| FBXO17 | F-box protein 17 | -0.0500337 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0477165 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0465768 |
| SBF2 | SET binding factor 2 | -0.0458402 |
| MYOF | myoferlin | -0.0415627 |
| CD44 | CD44 molecule (Indian blood group) | -0.0406728 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.039469 |
| CTSD | cathepsin D | -0.0389686 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0386303 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0385737 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0365097 |
| EGFR | epidermal growth factor receptor | -0.0354628 |
| CD109 | CD109 molecule | -0.0339717 |
| TXNRD1 | thioredoxin reductase 1 | -0.0328518 |
| CDCP1 | CUB domain containing protein 1 | -0.0326835 |
| PTK2 | protein tyrosine kinase 2 | -0.032543 |
| RPL35A | ribosomal protein L35a | -0.0321118 |
| MED13L | mediator complex subunit 13-like | -0.0320495 |
| ZNF292 | zinc finger protein 292 | -0.0318856 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0314037 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0311759 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0310926 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0310494 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0309132 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0307623 |
| EHBP1 | EH domain binding protein 1 | -0.0306777 |
| S100A6 | S100 calcium binding protein A6 | -0.0305557 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0297674 |
| PGK1 | phosphoglycerate kinase 1 | -0.029072 |
| WASF2 | WAS protein family, member 2 | -0.029039 |
| ACTN4 | actinin, alpha 4 | -0.0281366 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0279993 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0275007 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0272266 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0271602 |
| TCF12 | transcription factor 12 | -0.02674 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0264522 |
| CEP170 | centrosomal protein 170kDa | -0.0262503 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0258095 |
| PHF14 | PHD finger protein 14 | -0.0256729 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0256243 |
| FMNL2 | formin-like 2 | -0.0256105 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0255311 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0253899 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -0.0252231 |
| USP3 | ubiquitin specific peptidase 3 | -0.0250967 |
| ARRDC3 | arrestin domain containing 3 | -0.0250233 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0250139 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0249051 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0245024 |
| CDK19 | cyclin-dependent kinase 19 | -0.0244173 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.0243936 |
| ABLIM1 | actin binding LIM protein 1 | -0.0242899 |
| MAP4 | microtubule-associated protein 4 | -0.023956 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0239263 |
| RUNX1 | runt-related transcription factor 1 | -0.023725 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0237242 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0233933 |
| VGLL4 | vestigial-like family member 4 | -0.0233736 |
| XPO1 | exportin 1 | -0.02324 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0231125 |
| YEATS2 | YEATS domain containing 2 | -0.0229372 |
| WDR45B | WD repeat domain 45B | -0.0228936 |
| TLK1 | tousled-like kinase 1 | -0.0228508 |
| FOXO3 | forkhead box O3 | -0.0228416 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0227949 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0226863 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0225941 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0225837 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0223369 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0222457 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0220933 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0220459 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0219688 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0218025 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0216531 |
| ZFR | zinc finger RNA binding protein | -0.021582 |
| THOC2 | THO complex 2 | -0.0215067 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0214528 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.021435 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0213915 |
| CD47 | CD47 molecule | -0.0213129 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0211596 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0211349 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.02109 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0210784 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0209995 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0209904 |
| RNF38 | ring finger protein 38 | -0.0208232 |
| REEP3 | receptor accessory protein 3 | -0.0207876 |
