| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.146792 |
| LMO7 | LIM domain 7 | 0.132478 |
| LAMB3 | laminin, beta 3 | 0.125922 |
| TMSB4X | thymosin beta 4, X-linked | 0.102065 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.10122 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0880668 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0865606 |
| LAMC2 | laminin, gamma 2 | 0.0853384 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.075037 |
| RNF213 | ring finger protein 213 | 0.0745987 |
| HLA-B | major histocompatibility complex, class I, B | 0.0737889 |
| ACTG1 | actin gamma 1 | 0.072505 |
| AHNAK | AHNAK nucleoprotein | 0.0718859 |
| LAMA4 | laminin, alpha 4 | 0.0718461 |
| SQSTM1 | sequestosome 1 | 0.0707696 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0703141 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0697208 |
| PLEC | plectin | 0.066532 |
| KRT18 | keratin 18, type I | 0.065994 |
| DSPP | dentin sialophosphoprotein | 0.0655681 |
| SMAD3 | SMAD family member 3 | 0.0637829 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0635993 |
| SVIL | supervillin | 0.0634805 |
| PTMA | prothymosin, alpha | 0.0609242 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0607636 |
| DSG2 | desmoglein 2 | 0.0606996 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0594929 |
| CD44 | CD44 molecule (Indian blood group) | 0.0591421 |
| INTS6 | integrator complex subunit 6 | 0.0584524 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0576691 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0549432 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0545398 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0538927 |
| TXNIP | thioredoxin interacting protein | 0.0535194 |
| MYO1E | myosin IE | 0.0533813 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0528599 |
| RPS6 | ribosomal protein S6 | 0.0521507 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0508256 |
| CANX | calnexin | 0.0508138 |
| KRT8 | keratin 8, type II | 0.0489208 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0479317 |
| MYO5B | myosin VB | 0.0476137 |
| FN1 | fibronectin 1 | 0.0467896 |
| RPS3 | ribosomal protein S3 | 0.0467308 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0459667 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0456447 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.045604 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.045457 |
| SEPTIN9 | septin 9 | 0.0448087 |
| FMNL2 | formin-like 2 | 0.0446666 |
| NAV2 | neuron navigator 2 | 0.0433792 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0427222 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.042635 |
| CTBP2 | C-terminal binding protein 2 | 0.0425645 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0418898 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0418355 |
| TMSB10 | thymosin beta 10 | 0.0413891 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.041247 |
| EXT1 | exostosin glycosyltransferase 1 | 0.040978 |
| KRT7 | keratin 7, type II | 0.0408697 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0408061 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0402571 |
| KRT19 | keratin 19, type I | 0.0402064 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0394644 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0390193 |
| RPL19 | ribosomal protein L19 | 0.0390088 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.038988 |
| AFDN | afadin, adherens junction formation factor | 0.0387499 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0386787 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0385005 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0375748 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0365888 |
| TJP1 | tight junction protein 1 | 0.0365807 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0364855 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0362401 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0359943 |
| APP | amyloid beta (A4) precursor protein | 0.0357029 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0356679 |
| RPS8 | ribosomal protein S8 | 0.0356134 |
| G0S2 | G0/G1 switch 2 | 0.0354597 |
| EZR | ezrin | 0.0351592 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0351214 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0350907 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0350451 |
| RPL23 | ribosomal protein L23 | 0.0349753 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0349323 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0348964 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0334621 |
| SLC35F3 | solute carrier family 35, member F3 | 0.033452 |
| SP100 | SP100 nuclear antigen | 0.0332545 |
| RPL37A | ribosomal protein L37a | 0.0332291 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0330471 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0329664 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0329259 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0327407 |
| RPS21 | ribosomal protein S21 | 0.032308 |
| RPL37 | ribosomal protein L37 | 0.0322617 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0322181 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0319101 |
| EMP1 | epithelial membrane protein 1 | 0.031901 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.0455806 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0447784 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0423709 |
| HMGA1 | high mobility group AT-hook 1 | -0.0363241 |
| FOSL1 | FOS-like antigen 1 | -0.0234182 |
| TAPBP | TAP binding protein (tapasin) | -0.0213903 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0201208 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0191996 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0171557 |
| ATP11B | ATPase, class VI, type 11B | -0.0166922 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0166653 |
| CCNL1 | cyclin L1 | -0.0163879 |
| PCBP2 | poly(rC) binding protein 2 | -0.016342 |
| EGR1 | early growth response 1 | -0.0155607 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.0152946 |
| TXNRD1 | thioredoxin reductase 1 | -0.0144648 |
| ECT2 | epithelial cell transforming 2 | -0.0142962 |
| TMEM123 | transmembrane protein 123 | -0.014006 |
| LAMA5 | laminin, alpha 5 | -0.013944 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0137697 |
| MUC4 | mucin 4, cell surface associated | -0.0134152 |
| DIAPH3 | diaphanous-related formin 3 | -0.0128219 |
| GOLGA4 | golgin A4 | -0.0125115 |
| SMC4 | structural maintenance of chromosomes 4 | -0.012348 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0121814 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0120798 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0119367 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0119229 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0117165 |
| SRP54 | signal recognition particle 54kDa | -0.0116758 |
| USP3 | ubiquitin specific peptidase 3 | -0.0115404 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0115354 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0113707 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0112529 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0111369 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0111263 |
| RTN4 | reticulon 4 | -0.0110489 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0110479 |
| TGM2 | transglutaminase 2 | -0.0109685 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0108367 |
| TFG | TRK-fused gene | -0.0105652 |
| NUP58 | nucleoporin 58 | -0.0104453 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0104005 |
| ANXA3 | annexin A3 | -0.0103906 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0101706 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0101192 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0101138 |
| ANKRD28 | ankyrin repeat domain 28 | -0.00999562 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.00984455 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.00981091 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00964802 |
| ATN1 | atrophin 1 | -0.00959992 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.00930798 |
| CSPP1 | centrosome and spindle pole associated protein 1 | -0.00929221 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00927872 |
| PROSER2 | proline and serine rich 2 | -0.00905501 |
| SNX13 | sorting nexin 13 | -0.00902478 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.00902369 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.00890102 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.00887997 |
| ITGB4 | integrin, beta 4 | -0.00878817 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.00870561 |
| BAG6 | BCL2-associated athanogene 6 | -0.00866421 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.00861488 |
| NDFIP2 | Nedd4 family interacting protein 2 | -0.00849668 |
| CAV2 | caveolin 2 | -0.00844815 |
| RNF145 | ring finger protein 145 | -0.00841908 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.00831868 |
| KIF2A | kinesin heavy chain member 2A | -0.00827652 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.00827256 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | -0.00822248 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00817951 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00816109 |
| CDK8 | cyclin-dependent kinase 8 | -0.00812563 |
| RFX7 | regulatory factor X, 7 | -0.00807144 |
| DHFR | dihydrofolate reductase | -0.00805438 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.00799374 |
| UFM1 | ubiquitin-fold modifier 1 | -0.00799148 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | -0.00798792 |
| MTMR1 | myotubularin related protein 1 | -0.00790834 |
| C1ORF52 | chromosome 1 open reading frame 52 | -0.00788987 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.00788308 |
| SPIN4 | spindlin family, member 4 | -0.00787428 |
| DENND4A | DENN/MADD domain containing 4A | -0.00787079 |
| CLDN4 | claudin 4 | -0.00784178 |
| PTEN | phosphatase and tensin homolog | -0.00782951 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.00780508 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00779853 |
| DEPP1 | DEPP autophagy regulator 1 | -0.00778198 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.00773509 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | -0.00772286 |
| TMEM165 | transmembrane protein 165 | -0.0076846 |
| NOCT | nocturnin | -0.00762785 |
| USP33 | ubiquitin specific peptidase 33 | -0.00762522 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00761425 |
| ITGAV | integrin, alpha V | -0.00759291 |
| FOXM1 | forkhead box M1 | -0.0075878 |
| TBC1D12 | TBC1 domain family, member 12 | -0.00756541 |
| AXL | AXL receptor tyrosine kinase | -0.00752408 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00752332 |
