| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.187347 |
| ANGPTL4 | angiopoietin-like 4 | 0.085345 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.084534 |
| VEGFA | vascular endothelial growth factor A | 0.0751027 |
| NAV2 | neuron navigator 2 | 0.0739248 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0733825 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.071116 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0692587 |
| MT2A | metallothionein 2A | 0.0669419 |
| PLEC | plectin | 0.0651425 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0649333 |
| CD44 | CD44 molecule (Indian blood group) | 0.0640733 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.062259 |
| TMSB10 | thymosin beta 10 | 0.0603029 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0569501 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0555742 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0554772 |
| SMAD3 | SMAD family member 3 | 0.054857 |
| RRBP1 | ribosome binding protein 1 | 0.0543215 |
| FHIT | fragile histidine triad | 0.0538247 |
| SVIL | supervillin | 0.0528234 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0520262 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.051498 |
| SP100 | SP100 nuclear antigen | 0.0507315 |
| HDAC9 | histone deacetylase 9 | 0.0478815 |
| NCOR2 | nuclear receptor corepressor 2 | 0.047688 |
| ACTN1 | actinin, alpha 1 | 0.0469403 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0462667 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0460447 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0445366 |
| NRP1 | neuropilin 1 | 0.0437341 |
| H1-0 | H1.0 linker histone | 0.042494 |
| MSN | moesin | 0.0413684 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0402595 |
| FAT1 | FAT atypical cadherin 1 | 0.0401204 |
| NONO | non-POU domain containing, octamer-binding | 0.0401175 |
| BRD2 | bromodomain containing 2 | 0.0382363 |
| AHNAK | AHNAK nucleoprotein | 0.0377071 |
| MED13L | mediator complex subunit 13-like | 0.0376287 |
| IFI44L | interferon-induced protein 44-like | 0.037546 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0372844 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0371433 |
| SFTPA2 | surfactant protein A2 | 0.0367681 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0366895 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0365859 |
| SFPQ | splicing factor proline/glutamine-rich | 0.036409 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0362848 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0358647 |
| MCL1 | myeloid cell leukemia 1 | 0.0348968 |
| BRD4 | bromodomain containing 4 | 0.0347665 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0343045 |
| APP | amyloid beta (A4) precursor protein | 0.0338066 |
| FLNA | filamin A, alpha | 0.0336695 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0329057 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0325349 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0325045 |
| RBM39 | RNA binding motif protein 39 | 0.0324087 |
| IL6ST | interleukin 6 signal transducer | 0.0322475 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0321966 |
| ZNF644 | zinc finger protein 644 | 0.0321947 |
| CENPF | centromere protein F, 350/400kDa | 0.0320818 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0318293 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0316066 |
| PFKP | phosphofructokinase, platelet | 0.0312533 |
| ASPH | aspartate beta-hydroxylase | 0.0312385 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0309041 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0306147 |
| ACTN4 | actinin, alpha 4 | 0.0303314 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0303189 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0302061 |
| PMP22 | peripheral myelin protein 22 | 0.0301003 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0299655 |
| LMNA | lamin A/C | 0.0298704 |
| UTRN | utrophin | 0.02977 |
| CEP250 | centrosomal protein 250kDa | 0.0296733 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0296123 |
| SETBP1 | SET binding protein 1 | 0.0295479 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0293962 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0291074 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0290327 |
| DSCAM | Down syndrome cell adhesion molecule | 0.028864 |
| RUNX1 | runt-related transcription factor 1 | 0.0287211 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0287113 |
| KLC1 | kinesin light chain 1 | 0.0286477 |
| SDC4 | syndecan 4 | 0.028277 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.028131 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0281076 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0280914 |
| TPM3 | tropomyosin 3 | 0.027807 |
| TXNIP | thioredoxin interacting protein | 0.0273117 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0272966 |
| NF1 | neurofibromin 1 | 0.0272891 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0272044 |
| EHBP1 | EH domain binding protein 1 | 0.027162 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0271243 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0270463 |
| MX2 | MX dynamin-like GTPase 2 | 0.0270392 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0267544 |
| STK10 | serine/threonine kinase 10 | 0.0266728 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0266635 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.211065 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.131807 |
| FN1 | fibronectin 1 | -0.125011 |
| CDH13 | cadherin 13 | -0.110675 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.103331 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.102822 |
| TPM4 | tropomyosin 4 | -0.101105 |
| COL1A2 | collagen, type I, alpha 2 | -0.0933568 |
| STC1 | stanniocalcin 1 | -0.0889254 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0721315 |
| MMP12 | matrix metallopeptidase 12 | -0.0689933 |
| COL1A1 | collagen, type I, alpha 1 | -0.0686595 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0666465 |
| INHBA | inhibin, beta A | -0.0661879 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0607633 |
| ITGA1 | integrin, alpha 1 | -0.05979 |
| IL1B | interleukin 1, beta | -0.058556 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0575708 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0549938 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0546678 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0537968 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0518678 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0503654 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.04775 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0471876 |
| HLA-B | major histocompatibility complex, class I, B | -0.0456904 |
| TNNC1 | troponin C type 1 (slow) | -0.045163 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0447637 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0432506 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0427859 |
| PGK1 | phosphoglycerate kinase 1 | -0.0427772 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0407711 |
| LOXL2 | lysyl oxidase-like 2 | -0.0397899 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0391775 |
| TPM1 | tropomyosin 1 (alpha) | -0.0387476 |
| FRMD4A | FERM domain containing 4A | -0.0386462 |
| LOX | lysyl oxidase | -0.0378039 |
| THBS2 | thrombospondin 2 | -0.037434 |
| IER3 | immediate early response 3 | -0.0372065 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0369377 |
| CANX | calnexin | -0.036597 |
| CD109 | CD109 molecule | -0.0364326 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0362199 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0361391 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0357144 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0356642 |
| B2M | beta-2-microglobulin | -0.0348332 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0347905 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0340925 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0340054 |
| FTL | ferritin, light polypeptide | -0.0339877 |
| DNER | delta/notch-like EGF repeat containing | -0.0337778 |
| RPL35A | ribosomal protein L35a | -0.0330685 |
| PDE10A | phosphodiesterase 10A | -0.0330029 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.032936 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.0325547 |
| PTMA | prothymosin, alpha | -0.0324968 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0323474 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0319839 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.031254 |
| MMP2 | matrix metallopeptidase 2 | -0.0311396 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.030605 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0302834 |
| AMZ1 | archaelysin family metallopeptidase 1 | -0.0299156 |
| PCBP3 | poly(rC) binding protein 3 | -0.0297842 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0297182 |
| HM13 | histocompatibility (minor) 13 | -0.0296862 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0296702 |
| COL5A2 | collagen, type V, alpha 2 | -0.0295277 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.0290988 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0290713 |
| GLIS3 | GLIS family zinc finger 3 | -0.0289923 |
| SBF2 | SET binding factor 2 | -0.028593 |
| RAI14 | retinoic acid induced 14 | -0.0283074 |
| CALU | calumenin | -0.0282798 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0278079 |
| TMEM165 | transmembrane protein 165 | -0.02772 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -0.0272492 |
| CCDC138 | coiled-coil domain containing 138 | -0.0270074 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0266428 |
| GNAS | GNAS complex locus | -0.0265607 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0261978 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0255458 |
| ATP13A3 | ATPase type 13A3 | -0.0255036 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0254258 |
| KYNU | kynureninase | -0.0253953 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0247346 |
| INSIG2 | insulin induced gene 2 | -0.024566 |
| OXR1 | oxidation resistance 1 | -0.0242668 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0241239 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0239861 |
| RPS25 | ribosomal protein S25 | -0.0239258 |
| TWIST2 | twist family bHLH transcription factor 2 | -0.0239155 |
| KLF9 | Kruppel-like factor 9 | -0.0239087 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0236538 |
| FLOT1 | flotillin 1 | -0.0234216 |
| RIPOR3 | RIPOR family member 3 | -0.023377 |
| SNX14 | sorting nexin 14 | -0.0233563 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0230876 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0230071 |
