| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.193772 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.167776 |
| VGF | VGF nerve growth factor inducible | 0.142939 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.131657 |
| INHBA | inhibin, beta A | 0.109434 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0925541 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0903452 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.086028 |
| MCL1 | myeloid cell leukemia 1 | 0.0687177 |
| CNKSR3 | CNKSR family member 3 | 0.0684541 |
| ZFHX3 | zinc finger homeobox 3 | 0.0578047 |
| NBEA | neurobeachin | 0.0566534 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0543231 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0504406 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0503692 |
| AOPEP | aminopeptidase O (putative) | 0.0483047 |
| PAEP | progestagen-associated endometrial protein | 0.0478658 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0430431 |
| TOP1 | topoisomerase (DNA) I | 0.0416905 |
| ASPH | aspartate beta-hydroxylase | 0.0411016 |
| PCBP3 | poly(rC) binding protein 3 | 0.0394273 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0384302 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0380662 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0376722 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0365378 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0357019 |
| PTCHD4 | patched domain containing 4 | 0.0356084 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.0348863 |
| NCKAP5 | NCK-associated protein 5 | 0.0345109 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0344726 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0344671 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0338843 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0336555 |
| PALLD | palladin, cytoskeletal associated protein | 0.033524 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0331812 |
| SETX | senataxin | 0.0329722 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0326521 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0325217 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0324504 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.0324361 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0320909 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | 0.0319277 |
| FUS | FUS RNA binding protein | 0.0295305 |
| SIK2 | salt-inducible kinase 2 | 0.0294179 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0282247 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0281204 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0277348 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0276419 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0274204 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0266674 |
| HYOU1 | hypoxia up-regulated 1 | 0.0263807 |
| GOLGA3 | golgin A3 | 0.0263125 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.026295 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0262589 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0262123 |
| VCL | vinculin | 0.0260126 |
| H1-0 | H1.0 linker histone | 0.02598 |
| TMEM255B | transmembrane protein 255B | 0.0258609 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.025737 |
| PRPF3 | pre-mRNA processing factor 3 | 0.0248297 |
| SFMBT2 | Scm-like with four mbt domains 2 | 0.0246857 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0246136 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0239375 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.023736 |
| CORO1C | coronin, actin binding protein, 1C | 0.023684 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.02366 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0236216 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0233329 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | 0.0233232 |
| EP300 | E1A binding protein p300 | 0.0233221 |
| CDK13 | cyclin-dependent kinase 13 | 0.0232115 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0231178 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0230915 |
| SIK3 | SIK family kinase 3 | 0.0230226 |
| SGMS2 | sphingomyelin synthase 2 | 0.022979 |
| KLC1 | kinesin light chain 1 | 0.0224515 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0222332 |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit | 0.0221801 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0221573 |
| MAP7 | microtubule-associated protein 7 | 0.0216276 |
| SVIL | supervillin | 0.0215133 |
| TEX10 | testis expressed 10 | 0.0214495 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0213186 |
| NAV2 | neuron navigator 2 | 0.0212113 |
| NUP160 | nucleoporin 160kDa | 0.0211248 |
| FERMT2 | fermitin family member 2 | 0.0210861 |
| CUX1 | cut-like homeobox 1 | 0.0209399 |
| TMEM181 | transmembrane protein 181 | 0.0206931 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0206778 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 0.020473 |
| GOLGB1 | golgin B1 | 0.0204715 |
| GON4L | gon-4-like (C. elegans) | 0.0204424 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0203842 |
| TPP2 | tripeptidyl peptidase II | 0.0203631 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0201111 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0200998 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | 0.0200953 |
| NINL | ninein-like | 0.0200324 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0199829 |
| CTBP2 | C-terminal binding protein 2 | 0.0199457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.219436 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.147624 |
| ENO1 | enolase 1, (alpha) | -0.112489 |
| PEG10 | paternally expressed 10 | -0.0977161 |
| TENM1 | teneurin transmembrane protein 1 | -0.0945795 |
| PTMA | prothymosin, alpha | -0.0874909 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0823841 |
| POTEF | POTE ankyrin domain family, member F | -0.0693426 |
| NDRG1 | N-myc downstream regulated 1 | -0.0675323 |
| CALCA | calcitonin-related polypeptide alpha | -0.0646927 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0642106 |
| ZNF292 | zinc finger protein 292 | -0.0638748 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0628385 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0627246 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0574656 |
| CENPF | centromere protein F, 350/400kDa | -0.0542447 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0527602 |
| SYT1 | synaptotagmin I | -0.052706 |
| PCBP2 | poly(rC) binding protein 2 | -0.0503026 |
| ESRRG | estrogen-related receptor gamma | -0.0487114 |
| RPS3 | ribosomal protein S3 | -0.0472103 |
| RPS21 | ribosomal protein S21 | -0.0454252 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.044829 |
| RTN4 | reticulon 4 | -0.0440641 |
| RPS27A | ribosomal protein S27a | -0.0426187 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0414024 |
| RPS8 | ribosomal protein S8 | -0.0398522 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0397328 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0388747 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0387609 |
| PFN1 | profilin 1 | -0.0386124 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0381179 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0380704 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0376566 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0369786 |
| RPS6 | ribosomal protein S6 | -0.0351144 |
| FTL | ferritin, light polypeptide | -0.0348267 |
| PKM | pyruvate kinase, muscle | -0.0345945 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0336416 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0330652 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0328307 |
| RIT2 | Ras-like without CAAX 2 | -0.032817 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0326923 |
| SLC35F4 | solute carrier family 35, member F4 | -0.0325457 |
| RPS12 | ribosomal protein S12 | -0.0325151 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0323694 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0322875 |
| SEPTIN7 | septin 7 | -0.0322735 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0317255 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0316736 |
| RPL23 | ribosomal protein L23 | -0.0313461 |
| RPL26 | ribosomal protein L26 | -0.031299 |
| RPS25 | ribosomal protein S25 | -0.0311568 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0311497 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0309274 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0309186 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0305245 |
| RPLP1 | ribosomal protein, large, P1 | -0.0301847 |
| PCDH9 | protocadherin 9 | -0.0295927 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0295391 |
| XPO1 | exportin 1 | -0.0292652 |
| SNTG1 | syntrophin, gamma 1 | -0.0286527 |
| RPL37A | ribosomal protein L37a | -0.0285868 |
| RPL7 | ribosomal protein L7 | -0.0283661 |
| CCDC88A | coiled-coil domain containing 88A | -0.0281273 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.028038 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0278603 |
| HMGB3 | high mobility group box 3 | -0.0276754 |
| RPS17 | ribosomal protein S17 | -0.0276699 |
| RPL37 | ribosomal protein L37 | -0.02717 |
| GPC5 | glypican 5 | -0.0269647 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0266885 |
| UBC | ubiquitin C | -0.0266326 |
| NUP58 | nucleoporin 58 | -0.0265798 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0265412 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.026113 |
| S100A9 | S100 calcium binding protein A9 | -0.0257544 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.0256791 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0252216 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0248107 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0246187 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0242427 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0241981 |
| TXNIP | thioredoxin interacting protein | -0.0241954 |
| GPHN | gephyrin | -0.0241449 |
| RPL5 | ribosomal protein L5 | -0.0241444 |
| GNAS | GNAS complex locus | -0.023959 |
| RPL30 | ribosomal protein L30 | -0.0239496 |
| NFIA | nuclear factor I/A | -0.0239393 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0236829 |
| MT2A | metallothionein 2A | -0.0235343 |
| RPLP0 | ribosomal protein, large, P0 | -0.0234689 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0232734 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0231577 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0231349 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0230955 |
| LDHA | lactate dehydrogenase A | -0.0230952 |
| PDS5B | PDS5 cohesin associated factor B | -0.0228406 |
| DTNA | dystrobrevin, alpha | -0.0228051 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0226228 |
