| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Anethole trithione_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.132034 |
| HDAC9 | histone deacetylase 9 | 0.104963 |
| KYNU | kynureninase | 0.0961714 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.094236 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0806641 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0757085 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0745702 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0651814 |
| BICC1 | BicC family RNA binding protein 1 | 0.0648035 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0607541 |
| SFTPA2 | surfactant protein A2 | 0.0594919 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0584653 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0584185 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0569048 |
| TMSB10 | thymosin beta 10 | 0.0548673 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0545037 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.054458 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0540339 |
| HLA-B | major histocompatibility complex, class I, B | 0.0537872 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0521351 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.052135 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0511232 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0468417 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0440856 |
| DUSP10 | dual specificity phosphatase 10 | 0.0435386 |
| MT2A | metallothionein 2A | 0.0429572 |
| SP100 | SP100 nuclear antigen | 0.042258 |
| FNDC3B | fibronectin type III domain containing 3B | 0.041736 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0411762 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0411317 |
| ATXN1 | ataxin 1 | 0.0405378 |
| RPS4X | ribosomal protein S4, X-linked | 0.0400028 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0391281 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0389724 |
| STC1 | stanniocalcin 1 | 0.0380543 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0380157 |
| AHR | aryl hydrocarbon receptor | 0.0379681 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0376465 |
| NABP1 | nucleic acid binding protein 1 | 0.0373061 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0366665 |
| KLF12 | Kruppel-like factor 12 | 0.0365501 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0359556 |
| TXNIP | thioredoxin interacting protein | 0.0349156 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0342955 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0340372 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0338227 |
| INTS6 | integrator complex subunit 6 | 0.0329748 |
| SETX | senataxin | 0.0327872 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0324341 |
| SDC4 | syndecan 4 | 0.0318448 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0317196 |
| FLNA | filamin A, alpha | 0.031367 |
| SPAG9 | sperm associated antigen 9 | 0.0312831 |
| PRELID2 | PRELI domain containing 2 | 0.0312158 |
| NAV2 | neuron navigator 2 | 0.0311111 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0304124 |
| RASAL2 | RAS protein activator like 2 | 0.0303588 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0300329 |
| CLTC | clathrin, heavy chain (Hc) | 0.0298378 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0297755 |
| THBS1 | thrombospondin 1 | 0.0295553 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0289421 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0288162 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0286122 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0285926 |
| RPS12 | ribosomal protein S12 | 0.0284557 |
| FNIP1 | folliculin interacting protein 1 | 0.0283771 |
| PMP22 | peripheral myelin protein 22 | 0.0281089 |
| OGA | O-GlcNAcase | 0.0278553 |
| RPLP0 | ribosomal protein, large, P0 | 0.0278254 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0271401 |
| RPS3 | ribosomal protein S3 | 0.0270455 |
| HDAC8 | histone deacetylase 8 | 0.0269768 |
| MLPH | melanophilin | 0.0267792 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0267653 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0266792 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0265014 |
| RPL11 | ribosomal protein L11 | 0.0264969 |
| SMYD3 | SET and MYND domain containing 3 | 0.0263309 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0261974 |
| KIAA1217 | KIAA1217 | 0.0261778 |
| FRMD5 | FERM domain containing 5 | 0.0261712 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0260324 |
| BRD2 | bromodomain containing 2 | 0.0258985 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0257739 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0254348 |
| TLE4 | transducin-like enhancer of split 4 | 0.0253852 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0253353 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0253112 |
| GOLGA3 | golgin A3 | 0.0250542 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0249583 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.02494 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0249329 |
| RPL23 | ribosomal protein L23 | 0.0249062 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0247525 |
| NEK7 | NIMA-related kinase 7 | 0.0246657 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0246539 |
| RIGI | RNA sensor RIG-I | 0.0245249 |
| RPL7A | ribosomal protein L7a | 0.0244145 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.024321 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.185111 |
| COL6A3 | collagen, type VI, alpha 3 | -0.156765 |
| VCAN | versican | -0.153172 |
| NDRG1 | N-myc downstream regulated 1 | -0.132869 |
| FRMD4A | FERM domain containing 4A | -0.118689 |
| PDE10A | phosphodiesterase 10A | -0.116261 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.1027 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0952362 |
| VEGFA | vascular endothelial growth factor A | -0.0794786 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0713233 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0698628 |
| RAI14 | retinoic acid induced 14 | -0.0673849 |
| PGK1 | phosphoglycerate kinase 1 | -0.0656632 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0634957 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0634159 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0621258 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0480943 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0459084 |
| CADM1 | cell adhesion molecule 1 | -0.0457738 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0457049 |
| TPM4 | tropomyosin 4 | -0.0437859 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0426521 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0418277 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0417357 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0411506 |
| RTN4 | reticulon 4 | -0.0410693 |
| CDH13 | cadherin 13 | -0.0395741 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0390066 |
| DST | dystonin | -0.038697 |
| ENO1 | enolase 1, (alpha) | -0.0382405 |
| TMEM178B | transmembrane protein 178B | -0.0367806 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0349033 |
| ZNF292 | zinc finger protein 292 | -0.0341629 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.033926 |
| MMP12 | matrix metallopeptidase 12 | -0.0338118 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0329814 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0329657 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0324136 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0323713 |
| ASPH | aspartate beta-hydroxylase | -0.032283 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0321897 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0319752 |
| GPC6 | glypican 6 | -0.0316183 |
| TMEM132D | transmembrane protein 132D | -0.030519 |
| CD109 | CD109 molecule | -0.0304819 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0289475 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0284746 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0280793 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0279513 |
| SEPTIN7 | septin 7 | -0.02784 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0276013 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0274783 |
| GLIS3 | GLIS family zinc finger 3 | -0.0271418 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0268333 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0266767 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0261575 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0259484 |
| THBS2 | thrombospondin 2 | -0.025896 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0257376 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0256994 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0255481 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0254422 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0253517 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0251218 |
| NAV1 | neuron navigator 1 | -0.0250599 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0250156 |
| C3 | complement component 3 | -0.0249785 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0248466 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0244835 |
| NCKAP5 | NCK-associated protein 5 | -0.0244714 |
| EFNA5 | ephrin-A5 | -0.0243136 |
| ATP13A3 | ATPase type 13A3 | -0.0242357 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0239423 |
| CANX | calnexin | -0.0236029 |
| SCGB1D1 | secretoglobin, family 1D, member 1 | -0.0234997 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0233662 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0233274 |
| BNC2 | basonuclin 2 | -0.023282 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0231965 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0231926 |
| ZNF609 | zinc finger protein 609 | -0.0225562 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0224265 |
| EGFR | epidermal growth factor receptor | -0.0223876 |
| SLC38A1 | solute carrier family 38, member 1 | -0.022321 |
| PLIN2 | perilipin 2 | -0.0221031 |
| TPM1 | tropomyosin 1 (alpha) | -0.0220799 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0217961 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0215527 |
| PKM | pyruvate kinase, muscle | -0.0212187 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.021185 |
| CLMP | CXADR-like membrane protein | -0.0209058 |
| NGLY1 | N-glycanase 1 | -0.0208819 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.020717 |
| DIAPH2 | diaphanous-related formin 2 | -0.0207001 |
| SLC43A3 | solute carrier family 43, member 3 | -0.0203478 |
| CDCP1 | CUB domain containing protein 1 | -0.0200813 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0198478 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0197949 |
| LOXL2 | lysyl oxidase-like 2 | -0.0197842 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0197305 |
