| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.178226 |
| COL6A3 | collagen, type VI, alpha 3 | 0.147265 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.116753 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0840164 |
| VCL | vinculin | 0.0692464 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0653916 |
| HMGA2 | high mobility group AT-hook 2 | 0.0646733 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0531356 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0531224 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0531118 |
| SDC4 | syndecan 4 | 0.0518731 |
| HDLBP | high density lipoprotein binding protein | 0.0509876 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0500999 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0493206 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0478534 |
| PLEC | plectin | 0.0477869 |
| PRSS23 | protease, serine, 23 | 0.046242 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0457137 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0452924 |
| NRXN3 | neurexin 3 | 0.0446541 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0405884 |
| HLA-B | major histocompatibility complex, class I, B | 0.0397603 |
| ACTN1 | actinin, alpha 1 | 0.0385902 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0384832 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0376601 |
| INTS6 | integrator complex subunit 6 | 0.0371711 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0357014 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0350361 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0348848 |
| COL5A1 | collagen, type V, alpha 1 | 0.0348274 |
| MORF4L2 | mortality factor 4 like 2 | 0.0346588 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0345841 |
| SEC24D | SEC24 family member D | 0.0345442 |
| KYNU | kynureninase | 0.0339658 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0333227 |
| CMIP | c-Maf inducing protein | 0.0326391 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0325933 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0321551 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0314623 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0313472 |
| CD44 | CD44 molecule (Indian blood group) | 0.0313256 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0311161 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0306592 |
| FLNA | filamin A, alpha | 0.0298186 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0297908 |
| STK17A | serine/threonine kinase 17a | 0.0297503 |
| RRBP1 | ribosome binding protein 1 | 0.0295153 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0286349 |
| AHNAK | AHNAK nucleoprotein | 0.0280585 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.027983 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0278335 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0273626 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.027175 |
| PRELID2 | PRELI domain containing 2 | 0.0270925 |
| AHR | aryl hydrocarbon receptor | 0.0267669 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.026465 |
| NOTCH2 | notch 2 | 0.0262971 |
| TMEM263 | transmembrane protein 263 | 0.0262868 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0260073 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0257971 |
| PALLD | palladin, cytoskeletal associated protein | 0.0257699 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0256824 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0256546 |
| CAVIN1 | caveolae associated protein 1 | 0.0256166 |
| HYOU1 | hypoxia up-regulated 1 | 0.0254784 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0250481 |
| MYO9A | myosin IXA | 0.0250143 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0246744 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0246708 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0246226 |
| RAD51B | RAD51 paralog B | 0.0245355 |
| CCDC93 | coiled-coil domain containing 93 | 0.0243839 |
| SH3GL1 | SH3-domain GRB2-like 1 | 0.0242882 |
| CTBP2 | C-terminal binding protein 2 | 0.0238575 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0238363 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0236862 |
| GOLGA3 | golgin A3 | 0.0235755 |
| GOLGB1 | golgin B1 | 0.023256 |
| CREBBP | CREB binding protein | 0.0231694 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0229201 |
| HLA-C | major histocompatibility complex, class I, C | 0.022874 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0227975 |
| DIDO1 | death inducer-obliterator 1 | 0.0227927 |
| MYLK | myosin light chain kinase | 0.0227289 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0226685 |
| PMM2 | phosphomannomutase 2 | 0.0226439 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0226383 |
| TNNC1 | troponin C type 1 (slow) | 0.0224951 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0224746 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0223871 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0223801 |
| COL1A1 | collagen, type I, alpha 1 | 0.0223392 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0221401 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0221351 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0220565 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0219733 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0216942 |
| TMF1 | TATA element modulatory factor 1 | 0.0216919 |
| FAF2 | Fas associated factor family member 2 | 0.0216802 |
| CALU | calumenin | 0.0216648 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.321997 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116324 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.107397 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.105983 |
| POTEF | POTE ankyrin domain family, member F | -0.0966416 |
| FTL | ferritin, light polypeptide | -0.0944812 |
| VIM | vimentin | -0.0847843 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0702696 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0642027 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.062566 |
| NDRG1 | N-myc downstream regulated 1 | -0.0595726 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.059077 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0567881 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0528142 |
| ARRDC3 | arrestin domain containing 3 | -0.0525179 |
| RTN4 | reticulon 4 | -0.0493443 |
| FOSL1 | FOS-like antigen 1 | -0.0492779 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0487492 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0486651 |
| PKM | pyruvate kinase, muscle | -0.0480102 |
| TMSB10 | thymosin beta 10 | -0.0476884 |
| SEPTIN7 | septin 7 | -0.047576 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.04537 |
| RPS6 | ribosomal protein S6 | -0.0453463 |
| PGK1 | phosphoglycerate kinase 1 | -0.0440346 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0425839 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0414988 |
| FAM13A | family with sequence similarity 13, member A | -0.0410714 |
| IL6 | interleukin 6 | -0.0409924 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0407763 |
| RPL11 | ribosomal protein L11 | -0.0385056 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0381433 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0375 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0373155 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0343642 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0338918 |
| MATR3 | matrin 3 | -0.0337599 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0335445 |
| FMNL2 | formin-like 2 | -0.0335395 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0322716 |
| UBC | ubiquitin C | -0.03217 |
| KIF13A | kinesin family member 13A | -0.0315114 |
| TAGLN2 | transgelin 2 | -0.0308572 |
| ENO1 | enolase 1, (alpha) | -0.0306866 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0304794 |
| USP34 | ubiquitin specific peptidase 34 | -0.0301494 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0297974 |
| S100A6 | S100 calcium binding protein A6 | -0.0297128 |
| NOP58 | NOP58 ribonucleoprotein | -0.0293166 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0285086 |
| NBAS | neuroblastoma amplified sequence | -0.0284302 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0281104 |
| DOCK7 | dedicator of cytokinesis 7 | -0.0279967 |
| ANXA2 | annexin A2 | -0.0277292 |
| RNF145 | ring finger protein 145 | -0.0272879 |
| HIP1 | huntingtin interacting protein 1 | -0.0266401 |
| OLA1 | Obg-like ATPase 1 | -0.0263937 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0261759 |
| AFAP1 | actin filament associated protein 1 | -0.0261659 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0250671 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.024739 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.024703 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0244959 |
| RNF24 | ring finger protein 24 | -0.0244957 |
| TPM1 | tropomyosin 1 (alpha) | -0.0244576 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0239791 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0238598 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0237232 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0236724 |
| FNDC3B | fibronectin type III domain containing 3B | -0.023438 |
| LDHA | lactate dehydrogenase A | -0.0234208 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0233822 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0232235 |
| YBX1 | Y box binding protein 1 | -0.0230728 |
| SBF2 | SET binding factor 2 | -0.0230674 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0230507 |
| WDR43 | WD repeat domain 43 | -0.023006 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0229753 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0227956 |
| MMP12 | matrix metallopeptidase 12 | -0.022786 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0227297 |
| TMEM123 | transmembrane protein 123 | -0.0227233 |
| RPLP1 | ribosomal protein, large, P1 | -0.0226884 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0226043 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0225463 |
| MTPN | myotrophin | -0.0224357 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0222928 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -0.0221987 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0221033 |
| FAM168B | family with sequence similarity 168, member B | -0.0220542 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0216922 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0215552 |
| CBX3 | chromobox homolog 3 | -0.0214862 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | -0.0213887 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0213696 |
| RPL36A | ribosomal protein L36a | -0.0211945 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | -0.0211597 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0210002 |
| LNPK | lunapark, ER junction formation factor | -0.0209918 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.020877 |
