Anethole trithione_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Anethole trithione perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Anethole trithione_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MYH9 myosin, heavy chain 9, non-muscle 0.0840811
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0811167
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0646892
SAMD4A sterile alpha motif domain containing 4A 0.0641759
MACF1 microtubule-actin crosslinking factor 1 0.0613342
TNIP1 TNFAIP3 interacting protein 1 0.0612981
HDAC9 histone deacetylase 9 0.0581725
DSCAM Down syndrome cell adhesion molecule 0.0571634
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.056243
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0551811
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0541672
FLNA filamin A, alpha 0.0539544
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.051608
ZSWIM6 zinc finger, SWIM-type containing 6 0.0502336
SMAD3 SMAD family member 3 0.0499671
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0482203
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0478251
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0472862
BRD2 bromodomain containing 2 0.0469793
CAPRIN2 caprin family member 2 0.044529
ANXA1 annexin A1 0.0428684
NAP1L1 nucleosome assembly protein 1-like 1 0.0423199
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0421844
SET SET nuclear proto-oncogene 0.0421052
EEF2 eukaryotic translation elongation factor 2 0.0418055
SDC4 syndecan 4 0.0418011
LOC112694756 uncharaterized LOC112694756 0.0414212
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.041386
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0398838
MSN moesin 0.0396709
FLNB filamin B, beta 0.0393444
TM4SF1 transmembrane 4 L six family member 1 0.0388122
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0388049
HSPA8 heat shock 70kDa protein 8 0.0386722
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0380619
CPNE1 copine I 0.0366911
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0361594
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0360313
TCF25 transcription factor 25 (basic helix-loop-helix) 0.0354063
LMO7 LIM domain 7 0.0348578
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.034574
JARID2 jumonji, AT rich interactive domain 2 0.0341906
EXT1 exostosin glycosyltransferase 1 0.0331806
BIRC3 baculoviral IAP repeat containing 3 0.0330919
TLE4 transducin-like enhancer of split 4 0.0329719
OSMR oncostatin M receptor 0.0328301
CDK12 cyclin-dependent kinase 12 0.0328213
TMF1 TATA element modulatory factor 1 0.0323799
RAB10 RAB10, member RAS oncogene family 0.0320705
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0316988
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.0304688
SEC16A SEC16 homolog A (S. cerevisiae) 0.0300428
CSNK1A1 casein kinase 1, alpha 1 0.0297797
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0297185
PLEC plectin 0.0297074
AREG amphiregulin 0.0289294
NONO non-POU domain containing, octamer-binding 0.02857
CALR calreticulin 0.0280541
PRELID3B PRELI domain containing 3B 0.0279591
STIP1 stress-induced phosphoprotein 1 0.0278807
FXR1 fragile X mental retardation, autosomal homolog 1 0.0275783
NCEH1 neutral cholesterol ester hydrolase 1 0.0274275
CRY1 cryptochrome circadian clock 1 0.0272437
GPC5 glypican 5 0.0271909
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.0270046
TTC3 tetratricopeptide repeat domain 3 0.0269567
AKAP12 A kinase (PRKA) anchor protein 12 0.0267737
DGKD diacylglycerol kinase, delta 130kDa 0.0263941
DSPP dentin sialophosphoprotein 0.0263765
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.0262213
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0261779
CLIC4 chloride intracellular channel 4 0.0260571
SKP1 S-phase kinase-associated protein 1 0.0258458
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.025657
BMP6 bone morphogenetic protein 6 0.0254969
PMM2 phosphomannomutase 2 0.0253461
ANO6 anoctamin 6 0.0252995
FERMT2 fermitin family member 2 0.0250347
RHEB Ras homolog enriched in brain 0.0249135
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0248378
BICD1 bicaudal D homolog 1 (Drosophila) 0.0246873
MYO9A myosin IXA 0.0244701
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.0244511
HYOU1 hypoxia up-regulated 1 0.0239533
HOOK2 hook microtubule-tethering protein 2 0.0238833
APLP2 amyloid beta (A4) precursor-like protein 2 0.0238252
CSNK1G1 casein kinase 1, gamma 1 0.0238168
SMC1A structural maintenance of chromosomes 1A 0.023598
TMED9 transmembrane emp24 protein transport domain containing 9 0.0235958
EIF4A1 eukaryotic translation initiation factor 4A1 0.0234182
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.023414
H1-0 H1.0 linker histone 0.0232863
CTNNBL1 catenin, beta like 1 0.0232323
METTL16 methyltransferase like 16 0.0228575
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0228159
CDYL chromodomain protein, Y-like 0.0228071
LMNA lamin A/C 0.0227966
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0227381
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0225496
CAPN2 calpain 2, (m/II) large subunit 0.0224184

decreased expression

Symbol Name Standardized Value
VIM vimentin -0.162663
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.159253
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -0.103391
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0888345
NDRG1 N-myc downstream regulated 1 -0.0773398
ZMYND8 zinc finger, MYND-type containing 8 -0.0771686
ZBTB20 zinc finger and BTB domain containing 20 -0.0724606
MT2A metallothionein 2A -0.0700354
PKM pyruvate kinase, muscle -0.0669541
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0661565
IGF2 insulin-like growth factor 2 -0.0652876
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0579407
RPL35A ribosomal protein L35a -0.0574389
RAB7A RAB7A, member RAS oncogene family -0.0551492
FTH1 ferritin, heavy polypeptide 1 -0.0527271
RPLP1 ribosomal protein, large, P1 -0.0522372
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0484154
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0478557
EIF1 eukaryotic translation initiation factor 1 -0.04781
DNER delta/notch-like EGF repeat containing -0.0472451
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0470018
ZNF292 zinc finger protein 292 -0.0455114
PDE4D phosphodiesterase 4D, cAMP-specific -0.0452504
PFN1 profilin 1 -0.0445476
BHLHE40 basic helix-loop-helix family, member e40 -0.0426286
PYGL phosphorylase, glycogen, liver -0.0417408
STK24 serine/threonine kinase 24 -0.0416821
USP34 ubiquitin specific peptidase 34 -0.0415546
RBM25 RNA binding motif protein 25 -0.041534
RPL23 ribosomal protein L23 -0.0414546
RHOBTB3 Rho-related BTB domain containing 3 -0.0408517
RB1CC1 RB1-inducible coiled-coil 1 -0.0402535
PGK1 phosphoglycerate kinase 1 -0.0399702
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0394188
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0390781
TBC1D5 TBC1 domain family, member 5 -0.0386863
PNISR PNN-interacting serine/arginine-rich protein -0.0380805
RPLP2 ribosomal protein, large, P2 -0.0377582
BBX bobby sox homolog (Drosophila) -0.0356523
PTMA prothymosin, alpha -0.0352698
PHIP pleckstrin homology domain interacting protein -0.0352165
NAV2 neuron navigator 2 -0.0350252
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.034954
ARL15 ADP-ribosylation factor-like 15 -0.0345062
SOS1 son of sevenless homolog 1 (Drosophila) -0.034334
BCAS3 breast carcinoma amplified sequence 3 -0.0342316
IL1RAP interleukin 1 receptor accessory protein -0.0341916
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0335948
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0333193
ATG7 autophagy related 7 -0.0332381
CHD1 chromodomain helicase DNA binding protein 1 -0.0331921
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.0331431
PRELID2 PRELI domain containing 2 -0.0318928
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0317885
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0317729
CEP350 centrosomal protein 350kDa -0.0317384
RBM39 RNA binding motif protein 39 -0.03158
FBXO11 F-box protein 11 -0.0312454
APOLD1 apolipoprotein L domain containing 1 -0.0308942
RAD51B RAD51 paralog B -0.030786
NCOR1 nuclear receptor corepressor 1 -0.030726
SNX14 sorting nexin 14 -0.0307081
FER fer (fps/fes related) tyrosine kinase -0.0305177
ATXN2 ataxin 2 -0.0302388
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.030179
KTN1 kinectin 1 (kinesin receptor) -0.0299415
SMC4 structural maintenance of chromosomes 4 -0.0299241
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0297399
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0296587
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.029511
NCOA6 nuclear receptor coactivator 6 -0.0293856
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0292603
CCDC14 coiled-coil domain containing 14 -0.0292536
MBNL2 muscleblind-like splicing regulator 2 -0.0291
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.0290311
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0289678
TRA2A transformer 2 alpha homolog (Drosophila) -0.0285466
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0282819
MBD5 methyl-CpG binding domain protein 5 -0.0282324
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0281294
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0281076
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0278038
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0276868
SPIDR scaffolding protein involved in DNA repair -0.0274374
ATP5F1E ATP synthase F1 subunit epsilon -0.0271585
RPL12 ribosomal protein L12 -0.0270714
RSF1 remodeling and spacing factor 1 -0.0270699
GSK3B glycogen synthase kinase 3 beta -0.0270634
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0269657
TMSB10 thymosin beta 10 -0.0269227
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0266076
PIAS1 protein inhibitor of activated STAT, 1 -0.0265429
MON2 MON2 homolog (S. cerevisiae) -0.0262416
KIAA1671 KIAA1671 -0.0261939
ZFAND6 zinc finger, AN1-type domain 6 -0.026074
RDX radixin -0.0258706
PPP1R12A protein phosphatase 1, regulatory subunit 12A -0.0258201
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -0.0256875
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0255549
POTEF POTE ankyrin domain family, member F -0.0255333