| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.160533 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.109196 |
| RPS2 | ribosomal protein S2 | 0.106358 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.105374 |
| DSPP | dentin sialophosphoprotein | 0.0994539 |
| RPS6 | ribosomal protein S6 | 0.086792 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0816874 |
| MSN | moesin | 0.0813009 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0754413 |
| HSPA8 | heat shock 70kDa protein 8 | 0.073129 |
| PLEC | plectin | 0.0724869 |
| BCL2L1 | BCL2-like 1 | 0.0631833 |
| SEPTIN9 | septin 9 | 0.0587811 |
| RPL3 | ribosomal protein L3 | 0.0581253 |
| H1-4 | H1.4 linker histone, cluster member | 0.0556421 |
| EZR | ezrin | 0.0507129 |
| AXIN2 | axin 2 | 0.0500608 |
| MKI67 | marker of proliferation Ki-67 | 0.0471853 |
| SET | SET nuclear proto-oncogene | 0.0446358 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0439984 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0436552 |
| CENPF | centromere protein F, 350/400kDa | 0.0435771 |
| EGR1 | early growth response 1 | 0.0435725 |
| YAP1 | Yes-associated protein 1 | 0.0431976 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0428659 |
| RPS12 | ribosomal protein S12 | 0.042494 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0421195 |
| ACTN1 | actinin, alpha 1 | 0.0420639 |
| RPL21 | ribosomal protein L21 | 0.0402008 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0401447 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0399897 |
| TJP1 | tight junction protein 1 | 0.0391399 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0382834 |
| KRT18 | keratin 18, type I | 0.0378899 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0374663 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0370044 |
| MT2A | metallothionein 2A | 0.0367728 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0366412 |
| NONO | non-POU domain containing, octamer-binding | 0.0361573 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0358512 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0357453 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.0354437 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0345447 |
| LMO7 | LIM domain 7 | 0.0342419 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.034238 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0333602 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0327427 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0327288 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0324072 |
| BRD2 | bromodomain containing 2 | 0.0323213 |
| PNN | pinin, desmosome associated protein | 0.0323133 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0316383 |
| ANO6 | anoctamin 6 | 0.0315855 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0315471 |
| SMAD3 | SMAD family member 3 | 0.0313434 |
| MCC | mutated in colorectal cancers | 0.0308894 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0306916 |
| RCOR1 | REST corepressor 1 | 0.0305504 |
| CLTC | clathrin, heavy chain (Hc) | 0.0300458 |
| LAMA4 | laminin, alpha 4 | 0.0295614 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0293447 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0292134 |
| CPNE1 | copine I | 0.0289792 |
| YBX3 | Y box binding protein 3 | 0.0286353 |
| TGM2 | transglutaminase 2 | 0.0285844 |
| TPM3 | tropomyosin 3 | 0.0283607 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0280708 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.028028 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0279453 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.027565 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.027121 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0270741 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0270475 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0263167 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0262187 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0259658 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0259485 |
| RPS18 | ribosomal protein S18 | 0.0256694 |
| RPL7 | ribosomal protein L7 | 0.0255891 |
| RBP1 | retinol binding protein 1, cellular | 0.0255081 |
| CCNL1 | cyclin L1 | 0.0253954 |
| H1-5 | H1.5 linker histone, cluster member | 0.0253605 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0253293 |
| RPS3 | ribosomal protein S3 | 0.0249621 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0249469 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0248934 |
| RPL19 | ribosomal protein L19 | 0.0247904 |
| AFAP1L2 | actin filament associated protein 1-like 2 | 0.0245514 |
| TMF1 | TATA element modulatory factor 1 | 0.0244505 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0244335 |
| MYO10 | myosin X | 0.0244196 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0242958 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0242401 |
| VMP1 | vacuole membrane protein 1 | 0.0238842 |
| TPX2 | TPX2, microtubule-associated | 0.0238245 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0235505 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0235471 |
| ANLN | anillin, actin binding protein | 0.0234388 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.023325 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0232969 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.138771 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.108744 |
| CDH13 | cadherin 13 | -0.107424 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0900478 |
| RPS27A | ribosomal protein S27a | -0.0889304 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0832796 |
| ENO1 | enolase 1, (alpha) | -0.0802006 |
| TMSB10 | thymosin beta 10 | -0.078009 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0750179 |
| NAV2 | neuron navigator 2 | -0.0746183 |
| UBC | ubiquitin C | -0.0733778 |
| AHNAK | AHNAK nucleoprotein | -0.0699356 |
| RPL35A | ribosomal protein L35a | -0.0635816 |
| RUNX1 | runt-related transcription factor 1 | -0.0624314 |
| CANX | calnexin | -0.0621968 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0618042 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.060065 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0586818 |
| VIM | vimentin | -0.0585225 |
| PERP | PERP, TP53 apoptosis effector | -0.05833 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0580239 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.057521 |
| RPL23 | ribosomal protein L23 | -0.0536275 |
| CDK6 | cyclin-dependent kinase 6 | -0.053225 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0525991 |
| PCBP2 | poly(rC) binding protein 2 | -0.0499822 |
| PGK1 | phosphoglycerate kinase 1 | -0.047063 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.046363 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0455352 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0453676 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0447014 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0443841 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0441409 |
| HMGB1 | high mobility group box 1 | -0.0412429 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0408149 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0407078 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0404138 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0397868 |
| ANXA2 | annexin A2 | -0.0383323 |
| TMEM123 | transmembrane protein 123 | -0.0380576 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0367954 |
| KRT8 | keratin 8, type II | -0.0359388 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0357956 |
| LDHA | lactate dehydrogenase A | -0.0357177 |
| KIZ | kizuna centrosomal protein | -0.0353266 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0347845 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0343542 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.034098 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0339779 |
| AOPEP | aminopeptidase O (putative) | -0.0324677 |
| RPS24 | ribosomal protein S24 | -0.0324095 |
| HMGA1 | high mobility group AT-hook 1 | -0.031961 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0314553 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0313119 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0309733 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0308157 |
| CCND1 | cyclin D1 | -0.0302148 |
| MED13 | mediator complex subunit 13 | -0.0301209 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0300398 |
| CMIP | c-Maf inducing protein | -0.0296648 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0294901 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.029394 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0292839 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0291099 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0288715 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0285527 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0284788 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0281708 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0278697 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0276518 |
| ETNK1 | ethanolamine kinase 1 | -0.0275084 |
| HDAC8 | histone deacetylase 8 | -0.0273408 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0272747 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.027163 |
| GNAS | GNAS complex locus | -0.0270639 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0270437 |
| TPM4 | tropomyosin 4 | -0.0269325 |
| NF1 | neurofibromin 1 | -0.0268907 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0268739 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0268452 |
| ITGB4 | integrin, beta 4 | -0.0261434 |
| ZNF638 | zinc finger protein 638 | -0.0259736 |
| HDAC4 | histone deacetylase 4 | -0.0259644 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0259581 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0258685 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0258462 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0257442 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0257257 |
| TNS3 | tensin 3 | -0.0256374 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0255431 |
| RPLP1 | ribosomal protein, large, P1 | -0.0252557 |
| HDLBP | high density lipoprotein binding protein | -0.025148 |
| GLG1 | golgi glycoprotein 1 | -0.0250558 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0247498 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0243039 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0242915 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0242274 |
| UBB | ubiquitin B | -0.0241858 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0241694 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0241231 |
