| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Anethole trithione perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Anethole trithione_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.307473 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.150257 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.142575 |
| MYO10 | myosin X | 0.115332 |
| FNDC3B | fibronectin type III domain containing 3B | 0.108582 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.107302 |
| DST | dystonin | 0.0876006 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0791632 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0731602 |
| NAV2 | neuron navigator 2 | 0.0711877 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0705946 |
| TMSB10 | thymosin beta 10 | 0.0661363 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0630594 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0622248 |
| HDAC9 | histone deacetylase 9 | 0.0618794 |
| MT2A | metallothionein 2A | 0.0603644 |
| INTS6 | integrator complex subunit 6 | 0.0580091 |
| MSN | moesin | 0.0579159 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0560875 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0547981 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0534062 |
| PLEC | plectin | 0.0507425 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.050307 |
| VCL | vinculin | 0.0490379 |
| RUNX1 | runt-related transcription factor 1 | 0.0475134 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0474572 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0469681 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0467006 |
| RPS6 | ribosomal protein S6 | 0.0454444 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0450251 |
| FMNL2 | formin-like 2 | 0.0434874 |
| SFTPA2 | surfactant protein A2 | 0.0433548 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0424386 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0421697 |
| ASPH | aspartate beta-hydroxylase | 0.041332 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0405513 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0401701 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.040138 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0395008 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0393601 |
| OGA | O-GlcNAcase | 0.0392621 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0389762 |
| PTK2 | protein tyrosine kinase 2 | 0.0383381 |
| GPHN | gephyrin | 0.0374099 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0367239 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0363166 |
| SEPTIN9 | septin 9 | 0.0361727 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0361597 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0359488 |
| SLC38A2 | solute carrier family 38, member 2 | 0.035328 |
| SMYD3 | SET and MYND domain containing 3 | 0.0352073 |
| APP | amyloid beta (A4) precursor protein | 0.0350578 |
| PRELID2 | PRELI domain containing 2 | 0.0344783 |
| SPAG9 | sperm associated antigen 9 | 0.0344642 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0344119 |
| ACTN1 | actinin, alpha 1 | 0.0341531 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0335981 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0334351 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0332527 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0330939 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.032971 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.032851 |
| ANGPTL4 | angiopoietin-like 4 | 0.0328197 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0323608 |
| RPL3 | ribosomal protein L3 | 0.0323072 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0322962 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0314522 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0306784 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0306609 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0304794 |
| SEC24D | SEC24 family member D | 0.030467 |
| KLC1 | kinesin light chain 1 | 0.0303625 |
| KLF12 | Kruppel-like factor 12 | 0.0301659 |
| JAK1 | Janus kinase 1 | 0.0299553 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0298909 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0298045 |
| CLIC4 | chloride intracellular channel 4 | 0.0293694 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0293421 |
| MCL1 | myeloid cell leukemia 1 | 0.0291086 |
| HELZ | helicase with zinc finger | 0.0290861 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0289034 |
| TLE4 | transducin-like enhancer of split 4 | 0.0280457 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0277547 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0277174 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0276219 |
| CD44 | CD44 molecule (Indian blood group) | 0.0276129 |
| CALR | calreticulin | 0.027363 |
| TNS1 | tensin 1 | 0.0271319 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0270346 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0269685 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0268313 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0265672 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0263205 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0262342 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0262233 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0261889 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0259693 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.025859 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0256034 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0255089 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.205294 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.149592 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.142489 |
| HMGA2 | high mobility group AT-hook 2 | -0.125185 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.118634 |
| MMP1 | matrix metallopeptidase 1 | -0.115477 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.114963 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0865815 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0799504 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0719723 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0712249 |
| TPM4 | tropomyosin 4 | -0.0678312 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0635681 |
| OXR1 | oxidation resistance 1 | -0.0620985 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0587501 |
| STC1 | stanniocalcin 1 | -0.0576868 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0556929 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0530045 |
| COL1A2 | collagen, type I, alpha 2 | -0.0517543 |
| ATP13A3 | ATPase type 13A3 | -0.0461557 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0460166 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0455909 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0452419 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0449405 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0448863 |
| DIAPH2 | diaphanous-related formin 2 | -0.0448205 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0432206 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0424029 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0374492 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0372471 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0361089 |
| RAI14 | retinoic acid induced 14 | -0.0360455 |
| PRRX1 | paired related homeobox 1 | -0.0354386 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0341278 |
| RPL35A | ribosomal protein L35a | -0.0335238 |
| OSMR | oncostatin M receptor | -0.0320555 |
| NCKAP5 | NCK-associated protein 5 | -0.0320298 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.03126 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0311972 |
| CDH13 | cadherin 13 | -0.0309056 |
| LOXL2 | lysyl oxidase-like 2 | -0.0302414 |
| INSIG1 | insulin induced gene 1 | -0.0291831 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0276365 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0274832 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0270627 |
| MEIS1 | Meis homeobox 1 | -0.0266163 |
| GLIS3 | GLIS family zinc finger 3 | -0.0253589 |
| CCDC102B | coiled-coil domain containing 102B | -0.0252224 |
| LDHA | lactate dehydrogenase A | -0.0248931 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0248467 |
| VCAN | versican | -0.0248111 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.0247444 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0235174 |
| COL1A1 | collagen, type I, alpha 1 | -0.0231975 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0231326 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0226015 |
| FAM13A | family with sequence similarity 13, member A | -0.0225775 |
| PDE8A | phosphodiesterase 8A | -0.0224955 |
| NID2 | nidogen 2 (osteonidogen) | -0.0222187 |
| PRR16 | proline rich 16 | -0.0219666 |
| S100A6 | S100 calcium binding protein A6 | -0.0219238 |
| IGF2 | insulin-like growth factor 2 | -0.0218203 |
| HLA-E | major histocompatibility complex, class I, E | -0.0213584 |
| PLPP3 | phospholipid phosphatase 3 | -0.0212901 |
| FOSL1 | FOS-like antigen 1 | -0.0211107 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0210112 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0204445 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0203045 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0202616 |
| NDRG1 | N-myc downstream regulated 1 | -0.0199521 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0198533 |
| DNER | delta/notch-like EGF repeat containing | -0.019714 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0196133 |
| RPS25 | ribosomal protein S25 | -0.0193453 |
| WDR45B | WD repeat domain 45B | -0.0192561 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | -0.0192545 |
| PKM | pyruvate kinase, muscle | -0.0192422 |
| DSTN | destrin (actin depolymerizing factor) | -0.0191193 |
| CCND1 | cyclin D1 | -0.0191174 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0188811 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0188523 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.0187811 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0187701 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0187288 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0184141 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0183031 |
| PGK1 | phosphoglycerate kinase 1 | -0.0182802 |
| IL6 | interleukin 6 | -0.0180989 |
| ITGA1 | integrin, alpha 1 | -0.018092 |
| NOTCH3 | notch 3 | -0.0179928 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0178331 |
| NPTX1 | neuronal pentraxin I | -0.0177711 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0177383 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0176678 |
| CCDC91 | coiled-coil domain containing 91 | -0.0173554 |
| CA12 | carbonic anhydrase XII | -0.0172631 |
| TRAM1 | translocation associated membrane protein 1 | -0.0169394 |
| SNX6 | sorting nexin 6 | -0.0167301 |
| NREP | neuronal regeneration related protein | -0.0166858 |
| EDNRA | endothelin receptor type A | -0.0165161 |
