Aneuploidy Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description chromosome count is not an exact multiple of the haploid number (Mammalian Phenotype Ontology, MP_0004024)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D000782
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Genes

703 genes/proteins associated with the disease Aneuploidy from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TLX1 T-cell leukemia homeobox 1 2.88009
KIF11 kinesin family member 11 2.88009
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.59943
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.52237
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.50273
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 1.492
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.48761
CCNG1 cyclin G1 1.47608
INSIG1 insulin induced gene 1 1.46251
UGCG UDP-glucose ceramide glucosyltransferase 1.41992
ANXA8 annexin A8 1.41911
SELENBP1 selenium binding protein 1 1.41368
COMT catechol-O-methyltransferase 1.40842
CCND1 cyclin D1 1.39535
KRT4 keratin 4, type II 1.39479
CDKN2A cyclin-dependent kinase inhibitor 2A 1.39338
BRCA2 breast cancer 2, early onset 1.3931
BMP5 bone morphogenetic protein 5 1.3903
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.38918
ANXA3 annexin A3 1.38355
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.38213
THRSP thyroid hormone responsive 1.38156
CKB creatine kinase, brain 1.37648
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.36763
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.36591
MCM2 minichromosome maintenance complex component 2 1.36562
FDPS farnesyl diphosphate synthase 1.36361
HSPA1A heat shock 70kDa protein 1A 1.35962
PZP pregnancy-zone protein 1.35734
IDI1 isopentenyl-diphosphate delta isomerase 1 1.35705
PTTG1 pituitary tumor-transforming 1 1.35705
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.35705
TSC22D1 TSC22 domain family, member 1 1.35705
PLAA phospholipase A2-activating protein 1.35386
BAAT bile acid CoA:amino acid N-acyltransferase 1.34983
GLS2 glutaminase 2 (liver, mitochondrial) 1.34983
SDCBP syndecan binding protein (syntenin) 1.34983
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.34723
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 1.34635
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.34285
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 1.34285
G6PC glucose-6-phosphatase, catalytic subunit 1.34082
PDGFA platelet-derived growth factor alpha polypeptide 1.34082
NET1 neuroepithelial cell transforming 1 1.33612
LGALS3 lectin, galactoside-binding, soluble, 3 1.33612
ATF3 activating transcription factor 3 1.33287
SRSF5 serine/arginine-rich splicing factor 5 1.33257
HSPH1 heat shock 105kDa/110kDa protein 1 1.33022
OGG1 8-oxoguanine DNA glycosylase 1.32876
GLUL glutamate-ammonia ligase 1.32696
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.32637
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.31985
GNRHR gonadotropin-releasing hormone receptor 1.31656
BGN biglycan 1.31626
GADD45B growth arrest and DNA-damage-inducible, beta 1.31416
ACSL1 acyl-CoA synthetase long-chain family member 1 1.31119
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.31119
USP18 ubiquitin specific peptidase 18 1.3103
CROT carnitine O-octanoyltransferase 1.3103
SMC4 structural maintenance of chromosomes 4 1.3103
IHH indian hedgehog 1.3103
CYR61 cysteine-rich, angiogenic inducer, 61 1.3085
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 1.30819
SRXN1 sulfiredoxin 1 1.30727
SRSF2 serine/arginine-rich splicing factor 2 1.30727
ANXA1 annexin A1 1.30574
FKBP11 FK506 binding protein 11, 19 kDa 1.30421
ADK adenosine kinase 1.30147
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.29781
IER2 immediate early response 2 1.29564
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.29533
FAT1 FAT atypical cadherin 1 1.29533
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.29533
NDRG1 N-myc downstream regulated 1 1.29502
ALPL alkaline phosphatase, liver/bone/kidney 1.29502
PRIM1 primase, DNA, polypeptide 1 (49kDa) 1.29287
PTPRF protein tyrosine phosphatase, receptor type, F 1.29011
ERCC2 excision repair cross-complementation group 2 1.29011
GADD45A growth arrest and DNA-damage-inducible, alpha 1.28858
PRSS23 protease, serine, 23 1.28734
FMO5 flavin containing monooxygenase 5 1.28703
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.28456
EBP emopamil binding protein (sterol isomerase) 1.28425
ADPRHL2 ADP-ribosylhydrolase like 2 1.28333
NLE1 notchless homolog 1 (Drosophila) 1.28303
CNTFR ciliary neurotrophic factor receptor 1.28303
MGMT O-6-methylguanine-DNA methyltransferase 1.2821
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.2821
AR androgen receptor 1.2818
ATF4 activating transcription factor 4 1.28088
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 1.27936
KRT17 keratin 17, type I 1.27936
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 1.27936
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.2772
LEPROT leptin receptor overlapping transcript 1.27564
ADH6 alcohol dehydrogenase 6 (class V) 1.27564
VCAM1 vascular cell adhesion molecule 1 1.27409
NR5A2 nuclear receptor subfamily 5, group A, member 2 1.27409
ARRDC3 arrestin domain containing 3 1.27409
IGF1R insulin-like growth factor 1 receptor 1.27378
FABP4 fatty acid binding protein 4, adipocyte 1.27224
CTSD cathepsin D 1.27039
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.26917
NFIB nuclear factor I/B 1.26917
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.26917
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.26669
CXCL12 chemokine (C-X-C motif) ligand 12 1.26514
SDC2 syndecan 2 1.26175
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 1.26175
JUN jun proto-oncogene 1.26021
GCLC glutamate-cysteine ligase, catalytic subunit 1.25838
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.25745
TYMS thymidylate synthetase 1.25525
TCEA1 transcription elongation factor A (SII), 1 1.25494
MCM7 minichromosome maintenance complex component 7 1.25463
MT1A metallothionein 1A 1.25183
PRC1 protein regulator of cytokinesis 1 1.24997
IL1A interleukin 1, alpha 1.24997
MT2A metallothionein 2A 1.24966
GLRX glutaredoxin (thioltransferase) 1.2456
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.2456
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.2437
HEG1 heart development protein with EGF-like domains 1 1.2437
UBC ubiquitin C 1.2437
MPP1 membrane protein, palmitoylated 1, 55kDa 1.24275
GSTA3 glutathione S-transferase alpha 3 1.23899
GSTT1 glutathione S-transferase theta 1 1.23899
S100A10 S100 calcium binding protein A10 1.23712
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 1.23552
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.2352
FEM1B fem-1 homolog b (C. elegans) 1.23169
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 1.23169
RPS21 ribosomal protein S21 1.23137
UGDH UDP-glucose 6-dehydrogenase 1.23106
MYH2 myosin, heavy chain 2, skeletal muscle, adult 1.23106
CD9 CD9 molecule 1.23074
GJB2 gap junction protein, beta 2, 26kDa 1.22916
TMPO thymopoietin 1.22853
CD36 CD36 molecule (thrombospondin receptor) 1.2279
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.22664
ANKRD17 ankyrin repeat domain 17 1.22566
GDF15 growth differentiation factor 15 1.22566
MUC2 mucin 2, oligomeric mucus/gel-forming 1.22566
PTEN phosphatase and tensin homolog 1.22566
HSF2 heat shock transcription factor 2 1.22566
TGFBI transforming growth factor, beta-induced, 68kDa 1.22436
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.22274
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.22209
EGFR epidermal growth factor receptor 1.22145
GJA1 gap junction protein, alpha 1, 43kDa 1.2208
STAT1 signal transducer and activator of transcription 1, 91kDa 1.2208
BIRC6 baculoviral IAP repeat containing 6 1.22016
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.22016
CLU clusterin 1.21887
GJB1 gap junction protein, beta 1, 32kDa 1.21887
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.21887
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.21855
PER2 period circadian clock 2 1.21855
RBP1 retinol binding protein 1, cellular 1.21855
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.21855
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 1.21567
EEA1 early endosome antigen 1 1.21567
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.21468
BAG3 BCL2-associated athanogene 3 1.21468
MSH2 mutS homolog 2 1.21468
MCM5 minichromosome maintenance complex component 5 1.21076
RPL35A ribosomal protein L35a 1.21011
SEPT9 septin 9 1.20978
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.20881
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 1.20558
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.20526
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 1.20526
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.20526
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase 1.20526
PHB prohibitin 1.20493
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 1.20493
CLIC5 chloride intracellular channel 5 1.2046
ARL3 ADP-ribosylation factor-like 3 1.2046
PHB2 prohibitin 2 1.2046
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 1.20361
HSF1 heat shock transcription factor 1 1.20163
CDC25B cell division cycle 25B 1.2013
PLEKHO1 pleckstrin homology domain containing, family O member 1 1.19999
PLK2 polo-like kinase 2 1.19999
SLC38A3 solute carrier family 38, member 3 1.19999
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 1.19933
LPL lipoprotein lipase 1.19802
S100A6 S100 calcium binding protein A6 1.1977
HNF4A hepatocyte nuclear factor 4, alpha 1.19607
COQ3 coenzyme Q3 methyltransferase 1.19607
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.19607
ERCC3 excision repair cross-complementation group 3 1.19574
TCEA3 transcription elongation factor A (SII), 3 1.19542
SLC44A4 solute carrier family 44, member 4 1.19542
NPR2 natriuretic peptide receptor 2 1.19542
CREM cAMP responsive element modulator 1.19445
HBB hemoglobin, beta 1.19246
ALPP alkaline phosphatase, placental 1.19146
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.19113
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.19047
MGP matrix Gla protein 1.18882
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.18718
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.18718
SCAMP1 secretory carrier membrane protein 1 1.18685
VASN vasorin 1.1862
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 1.1862
DHCR7 7-dehydrocholesterol reductase 1.18554
UBE2C ubiquitin-conjugating enzyme E2C 1.18554
FGA fibrinogen alpha chain 1.18554
SOD1 superoxide dismutase 1, soluble 1.18259
GGT1 gamma-glutamyltransferase 1 1.18226
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.18226
DMGDH dimethylglycine dehydrogenase 1.18193
MYBBP1A MYB binding protein (P160) 1a 1.18193
PTPN21 protein tyrosine phosphatase, non-receptor type 21 1.18193
RPL41 ribosomal protein L41 1.18193
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 1.18193
HSPE1 heat shock 10kDa protein 1 1.18059
CSNK1E casein kinase 1, epsilon 1.17794
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.17761
SEC62 SEC62 homolog (S. cerevisiae) 1.17761
PELO pelota homolog (Drosophila) 1.17761
LACTB2 lactamase, beta 2 1.17761
RHOB ras homolog family member B 1.17728
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.17662
NRG1 neuregulin 1 1.17563
CLDN22 claudin 22 1.17497
AQP1 aquaporin 1 (Colton blood group) 1.17399
CCNE2 cyclin E2 1.17399
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.17399
RPS24 ribosomal protein S24 1.17399
DEFB1 defensin, beta 1 1.17366
RPA3 replication protein A3, 14kDa 1.17333
PGD phosphogluconate dehydrogenase 1.17268
FKBP5 FK506 binding protein 5 1.17235
MT-ATP6 ATP synthase F0 subunit 6 1.17168
OAT ornithine aminotransferase 1.17101
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.17
HGD homogentisate 1,2-dioxygenase 1.16967
RPL13A ribosomal protein L13a 1.16933
TPM1 tropomyosin 1 (alpha) 1.169
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.16833
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.16766
SQLE squalene epoxidase 1.16633
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 1.166
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.166
PARD3 par-3 family cell polarity regulator 1.16567
UCK2 uridine-cytidine kinase 2 1.16533
XPO1 exportin 1 1.16533
KRT13 keratin 13, type I 1.16533
FETUB fetuin B 1.16533
TP53 tumor protein p53 1.16467
HMOX1 heme oxygenase 1 1.16401
IGFBP5 insulin-like growth factor binding protein 5 1.16302
LRP5 low density lipoprotein receptor-related protein 5 1.16203
TM4SF4 transmembrane 4 L six family member 4 1.1617
CRYM crystallin, mu 1.1617
MAPRE1 microtubule-associated protein, RP/EB family, member 1 1.16137
PASK PAS domain containing serine/threonine kinase 1.16137
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.15797
PSME4 proteasome (prosome, macropain) activator subunit 4 1.15797
VAMP8 vesicle-associated membrane protein 8 1.15797
RAB30 RAB30, member RAS oncogene family 1.15763
COX6C cytochrome c oxidase subunit VIc 1.15763
KIF1A kinesin family member 1A 1.15763
MBD1 methyl-CpG binding domain protein 1 1.15458
ABLIM1 actin binding LIM protein 1 1.15425
F13A1 coagulation factor XIII, A1 polypeptide 1.15425
CABLES1 Cdk5 and Abl enzyme substrate 1 1.15391
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 1.15391
PPP1R3B protein phosphatase 1, regulatory subunit 3B 1.15391
CALR calreticulin 1.15223
AEN apoptosis enhancing nuclease 1.15089
FTCD formimidoyltransferase cyclodeaminase 1.15055
ARRDC2 arrestin domain containing 2 1.15055
MEST mesoderm specific transcript 1.15022
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 1.15022
RGS2 regulator of G-protein signaling 2 1.14989
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.14954
LDHA lactate dehydrogenase A 1.14954
PKM pyruvate kinase, muscle 1.14678
FGL1 fibrinogen-like 1 1.14644
RAD51 RAD51 recombinase 1.14644
RRAS related RAS viral (r-ras) oncogene homolog 1.14644
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.14644
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.14438
MET MET proto-oncogene, receptor tyrosine kinase 1.1437
LEP leptin 1.1437
GPX2 glutathione peroxidase 2 1.1437
APAF1 apoptotic peptidase activating factor 1 1.1437
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 1.14336
CST6 cystatin E/M 1.14302
KLKB1 kallikrein B, plasma (Fletcher factor) 1 1.14302
BLNK B-cell linker 1.14302
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 1.14302
ANXA2 annexin A2 1.14234
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.14098
NNMT nicotinamide N-methyltransferase 1.13963
OLFM1 olfactomedin 1 1.13963
ATPIF1 ATPase inhibitory factor 1 1.13963
RPL27A ribosomal protein L27a 1.13689
FGL2 fibrinogen-like 2 1.13655
CTTN cortactin 1.13655
EMP2 epithelial membrane protein 2 1.13621
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 1.13621
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 1.13621
CDC34 cell division cycle 34 1.13621
FABP1 fatty acid binding protein 1, liver 1.13518
TLR2 toll-like receptor 2 1.13518
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.13449
PRDX1 peroxiredoxin 1 1.13381
TGFBR3 transforming growth factor, beta receptor III 1.13347
DFNA5 deafness, autosomal dominant 5 1.13313
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.13313
GARS glycyl-tRNA synthetase 1.13279
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 1.13279
GYS2 glycogen synthase 2 (liver) 1.13279
RPS27 ribosomal protein S27 1.13279
RHOU ras homolog family member U 1.13279
RAB14 RAB14, member RAS oncogene family 1.13041
PPP1R37 protein phosphatase 1, regulatory subunit 37 1.13007
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.13007
PTH1R parathyroid hormone 1 receptor 1.13007
RRM2 ribonucleotide reductase M2 1.12973
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1.12973
BHLHE41 basic helix-loop-helix family, member e41 1.12973
EPS8 epidermal growth factor receptor pathway substrate 8 1.1294
CCNB2 cyclin B2 1.12737
KRT14 keratin 14, type I 1.12737
G6PD glucose-6-phosphate dehydrogenase 1.12737
PTMS parathymosin 1.12668
EIF3B eukaryotic translation initiation factor 3, subunit B 1.12668
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.12634
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 1.12634
AFP alpha-fetoprotein 1.12495
GM2A GM2 ganglioside activator 1.12357
COL3A1 collagen, type III, alpha 1 1.12357
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 1.12323
GPX3 glutathione peroxidase 3 1.12185
HSPA1B heat shock 70kDa protein 1B 1.12082
SLC39A10 solute carrier family 39 (zinc transporter), member 10 1.12048
AGXT alanine-glyoxylate aminotransferase 1.12048
HNMT histamine N-methyltransferase 1.1198
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.11843
PGK2 phosphoglycerate kinase 2 1.11775
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13 1.11741
ANKRD12 ankyrin repeat domain 12 1.11707
NT5DC2 5'-nucleotidase domain containing 2 1.11707
COL1A1 collagen, type I, alpha 1 1.11571
LXN latexin 1.11466
STAT2 signal transducer and activator of transcription 2, 113kDa 1.11396
MRC1 mannose receptor, C type 1 1.11396
PDLIM1 PDZ and LIM domain 1 1.11396
SPON1 spondin 1, extracellular matrix protein 1.11396
SGK1 serum/glucocorticoid regulated kinase 1 1.1136
VEGFA vascular endothelial growth factor A 1.11325
PRDX4 peroxiredoxin 4 1.11255
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 1.11186
VTN vitronectin 1.11116
RB1 retinoblastoma 1 1.11081
CNN3 calponin 3, acidic 1.11081
CES1 carboxylesterase 1 1.11081
FOXQ1 forkhead box Q1 1.11081
TFF1 trefoil factor 1 1.11011
XBP1 X-box binding protein 1 1.10942
PCSK5 proprotein convertase subtilisin/kexin type 5 1.10907
GAS1 growth arrest-specific 1 1.10872
DST dystonin 1.10872
LY6E lymphocyte antigen 6 complex, locus E 1.10803
ERCC5 excision repair cross-complementation group 5 1.10803
C9 complement component 9 1.10803
TRIB3 tribbles pseudokinase 3 1.10699
KRAS Kirsten rat sarcoma viral oncogene homolog 1.10596
GSTM1 glutathione S-transferase mu 1 1.10562
TUBGCP2 tubulin, gamma complex associated protein 2 1.10562
LEPR leptin receptor 1.10527
CDCA5 cell division cycle associated 5 1.10527
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 1.10527
LAMA3 laminin, alpha 3 1.10527
BTG2 BTG family, member 2 1.10493
PNRC1 proline-rich nuclear receptor coactivator 1 1.10493
SMC2 structural maintenance of chromosomes 2 1.10282
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.10282
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 1.10282
CHKA choline kinase alpha 1.10246
PPIF peptidylprolyl isomerase F 1.10211
PARP1 poly (ADP-ribose) polymerase 1 1.10211
JUP junction plakoglobin 1.10211
PRMT1 protein arginine methyltransferase 1 1.10211
ZBTB16 zinc finger and BTB domain containing 16 1.10211
NSDHL NAD(P) dependent steroid dehydrogenase-like 1.10211
PCNA proliferating cell nuclear antigen 1.10069
KIFC1 kinesin family member C1 1.09998
PLSCR1 phospholipid scramblase 1 1.09927
PA2G4 proliferation-associated 2G4, 38kDa 1.09927
WISP2 WNT1 inducible signaling pathway protein 2 1.09927
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.09857
ESR2 estrogen receptor 2 (ER beta) 1.09751
MTUS1 microtubule associated tumor suppressor 1 1.09681
MAP1S microtubule-associated protein 1S 1.09681
CXCL11 chemokine (C-X-C motif) ligand 11 1.09681
USP2 ubiquitin specific peptidase 2 1.09681
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.09681
CAPG capping protein (actin filament), gelsolin-like 1.09681
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 1.09646
EIF1B eukaryotic translation initiation factor 1B 1.09576
CELA3B chymotrypsin-like elastase family, member 3B 1.09576
PARD3B par-3 family cell polarity regulator beta 1.09576
ASB5 ankyrin repeat and SOCS box containing 5 1.09541
TIMP2 TIMP metallopeptidase inhibitor 2 1.09506
STAP1 signal transducing adaptor family member 1 1.09506
EGR1 early growth response 1 1.09436
TOB1 transducer of ERBB2, 1 1.09401
TMPRSS2 transmembrane protease, serine 2 1.09401
RBBP4 retinoblastoma binding protein 4 1.09401
ESR1 estrogen receptor 1 1.09262
PDZK1 PDZ domain containing 1 1.09226
LUM lumican 1.0919
SPAG5 sperm associated antigen 5 1.09154
AHCY adenosylhomocysteinase 1.09154
TFF3 trefoil factor 3 (intestinal) 1.09119
FBLN1 fibulin 1 1.09119
COL1A2 collagen, type I, alpha 2 1.0894
COL5A2 collagen, type V, alpha 2 1.08868
KYNU kynureninase 1.08833
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.08833
AKAP9 A kinase (PRKA) anchor protein 9 1.08833
TTC4 tetratricopeptide repeat domain 4 1.08762
SH2D2A SH2 domain containing 2A 1.0869
PEBP1 phosphatidylethanolamine binding protein 1 1.08619
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.08584
RAD54L2 RAD54-like 2 (S. cerevisiae) 1.08584
SCAMP4 secretory carrier membrane protein 4 1.08549
SRFBP1 serum response factor binding protein 1 1.08513
ZNF655 zinc finger protein 655 1.08513
HMGA2 high mobility group AT-hook 2 1.08407
MLH1 mutL homolog 1 1.08407
CPE carboxypeptidase E 1.08337
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 1.08337
MAPK3 mitogen-activated protein kinase 3 1.08266
ACADL acyl-CoA dehydrogenase, long chain 1.08126
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.08126
GPER1 G protein-coupled estrogen receptor 1 1.08091
TALDO1 transaldolase 1 1.08055
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.07983
MECP2 methyl CpG binding protein 2 1.07947
IL33 interleukin 33 1.07911
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 1.07911
ZMAT3 zinc finger, matrin-type 3 1.07875
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 1.07875
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 1.07875
MVP major vault protein 1.0784
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.0784
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 1.0784
CFH complement factor H 1.07804
DOHH deoxyhypusine hydroxylase/monooxygenase 1.07804
FBXW9 F-box and WD repeat domain containing 9 1.07768
SEC16A SEC16 homolog A (S. cerevisiae) 1.07768
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 1.07768
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.07625
PAH phenylalanine hydroxylase 1.07589
TNF tumor necrosis factor 1.07589
FMO3 flavin containing monooxygenase 3 1.07589
N4BP3 NEDD4 binding protein 3 1.07589
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.07589
MAPK1 mitogen-activated protein kinase 1 1.07589
ZFP36L1 ZFP36 ring finger protein-like 1 1.07553
MXD1 MAX dimerization protein 1 1.07411
ALAS2 5'-aminolevulinate synthase 2 1.07376
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.07376
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 1.07376
IFNGR1 interferon gamma receptor 1 1.07376
IGFBP3 insulin-like growth factor binding protein 3 1.07305
GMNN geminin, DNA replication inhibitor 1.07305
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.07305
IL6 interleukin 6 1.07305
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.07199
LTB lymphotoxin beta (TNF superfamily, member 3) 1.07128
AK4 adenylate kinase 4 1.07128
ECE1 endothelin converting enzyme 1 1.07128
AMPD3 adenosine monophosphate deaminase 3 1.07093
SIRT1 sirtuin 1 1.07093
GSTK1 glutathione S-transferase kappa 1 1.07093
COL6A1 collagen, type VI, alpha 1 1.07093
ERP29 endoplasmic reticulum protein 29 1.07093
XPA xeroderma pigmentosum, complementation group A 1.06952
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.06952
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.06917
RNASE4 ribonuclease, RNase A family, 4 1.06917
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.06917
LYN LYN proto-oncogene, Src family tyrosine kinase 1.06881
RTN4 reticulon 4 1.06881
CDCA8 cell division cycle associated 8 1.06844
CYTH2 cytohesin 2 1.06844
CASKIN1 CASK interacting protein 1 1.06844
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 1.06844
ZCCHC14 zinc finger, CCHC domain containing 14 1.06844
LRP1 low density lipoprotein receptor-related protein 1 1.06844
LAPTM4A lysosomal protein transmembrane 4 alpha 1.06771
FOS FBJ murine osteosarcoma viral oncogene homolog 1.06698
KLHL24 kelch-like family member 24 1.06661
RCAN1 regulator of calcineurin 1 1.06661
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.06625
ALDOB aldolase B, fructose-bisphosphate 1.06625
CSF1R colony stimulating factor 1 receptor 1.06625
TUBB6 tubulin, beta 6 class V 1.06588
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 1.06588
MAT2A methionine adenosyltransferase II, alpha 1.06479
KRT10 keratin 10, type I 1.0637
DBP D site of albumin promoter (albumin D-box) binding protein 1.0637
MAT1A methionine adenosyltransferase I, alpha 1.0637
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.0637
UBD ubiquitin D 1.0637
PPP1R3C protein phosphatase 1, regulatory subunit 3C 1.06188
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.06152
FHL2 four and a half LIM domains 2 1.06152
EGLN3 egl-9 family hypoxia-inducible factor 3 1.06152
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.06116
VMO1 vitelline membrane outer layer 1 homolog (chicken) 1.06044
CCDC132 coiled-coil domain containing 132 1.06008
TMEM55A transmembrane protein 55A 1.06008
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1.05972
ARL6 ADP-ribosylation factor-like 6 1.05936
ACAT1 acetyl-CoA acetyltransferase 1 1.05936
CRP C-reactive protein, pentraxin-related 1.05936
IRS4 insulin receptor substrate 4 1.05936
CISH cytokine inducible SH2-containing protein 1.05936
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene 1.05936
VNN1 vanin 1 1.059
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.059
MKI67 marker of proliferation Ki-67 1.05757
WNT4 wingless-type MMTV integration site family, member 4 1.05757
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.05685
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.05648
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.05648
HSPA8 heat shock 70kDa protein 8 1.05573
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.05498
TGIF1 TGFB-induced factor homeobox 1 1.05461
RORA RAR-related orphan receptor A 1.05423
RGS16 regulator of G-protein signaling 16 1.05423
ZWINT ZW10 interacting kinetochore protein 1.05237
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.05237
PROM1 prominin 1 1.052
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.052
RPSA ribosomal protein SA 1.052
TMEM184B transmembrane protein 184B 1.05163
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 1.05126
GSR glutathione reductase 1.05126
NRIP1 nuclear receptor interacting protein 1 1.05089
GATA6 GATA binding protein 6 1.05089
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.05015
NREP neuronal regeneration related protein 1.04978
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 1.04978
APOA1 apolipoprotein A-I 1.04978
TOP2A topoisomerase (DNA) II alpha 170kDa 1.04941
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.04868
BAD BCL2-associated agonist of cell death 1.04868
PIR pirin (iron-binding nuclear protein) 1.04831
ACOT1 acyl-CoA thioesterase 1 1.04794
KITLG KIT ligand 1.04794
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.04757
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.04757
ALPPL2 alkaline phosphatase, placental-like 2 1.04757
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.04757
LTA lymphotoxin alpha 1.04611
F5 coagulation factor V (proaccelerin, labile factor) 1.04611
ACAT2 acetyl-CoA acetyltransferase 2 1.04574
ADA adenosine deaminase 1.04574
SLC38A2 solute carrier family 38, member 2 1.04574
ACP5 acid phosphatase 5, tartrate resistant 1.04574
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.04538
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.04501
A1CF APOBEC1 complementation factor 1.04465
MSH6 mutS homolog 6 1.04427
UROC1 urocanate hydratase 1 1.04389
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.04389
CLIC2 chloride intracellular channel 2 1.04352
SCGB2A2 secretoglobin, family 2A, member 2 1.04352
RAB11FIP2 RAB11 family interacting protein 2 (class I) 1.04314
SIX3 SIX homeobox 3 1.04314
LITAF lipopolysaccharide-induced TNF factor 1.04163
TKT transketolase 1.04163
VWF von Willebrand factor 1.04163
CBR3 carbonyl reductase 3 1.04163
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.04126
ACTG1 actin gamma 1 1.04126
CTSS cathepsin S 1.04126
CFL1 cofilin 1 (non-muscle) 1.04126
EREG epiregulin 1.03901
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.03901
EPCAM epithelial cell adhesion molecule 1.03901
HSPB8 heat shock 22kDa protein 8 1.03901
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 1.03827
STIP1 stress-induced phosphoprotein 1 1.03752
FMN1 formin 1 1.03715
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 1.03715
RNF170 ring finger protein 170 1.03715
TBC1D7 TBC1 domain family, member 7 1.03715
PDIA4 protein disulfide isomerase family A, member 4 1.03678
CTSC cathepsin C 1.03678
LIPC lipase, hepatic 1.03678
FUT2 fucosyltransferase 2 (secretor status included) 1.03641
GTPBP3 GTP binding protein 3 (mitochondrial) 1.03641
NIPSNAP3A nipsnap homolog 3A (C. elegans) 1.03641
RTN2 reticulon 2 1.03641
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.03641
TMPRSS3 transmembrane protease, serine 3 1.03641
ANXA10 annexin A10 1.03641
ASS1 argininosuccinate synthase 1 1.03493
CFB complement factor B 1.03493
RAD50 RAD50 homolog (S. cerevisiae) 1.03345
FADS1 fatty acid desaturase 1 1.03308
CENPF centromere protein F, 350/400kDa 1.03271
RAN RAN, member RAS oncogene family 1.03271
EMP1 epithelial membrane protein 1 1.03271
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.03159
ZIC2 Zic family member 2 1.03122
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 1.03122
NTF3 neurotrophin 3 1.03122
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.03084
SPHK1 sphingosine kinase 1 1.03084
AKAP17A A kinase (PRKA) anchor protein 17A 1.03046
PRPF4 pre-mRNA processing factor 4 1.03009
PPP1R16B protein phosphatase 1, regulatory subunit 16B 1.03009
ANKRD29 ankyrin repeat domain 29 1.03009
DUSP1 dual specificity phosphatase 1 1.02971
FAM89A family with sequence similarity 89, member A 1.02933
ETNK2 ethanolamine kinase 2 1.02933
VEPH1 ventricular zone expressed PH domain-containing 1 1.02933
LOXL4 lysyl oxidase-like 4 1.02933
MED20 mediator complex subunit 20 1.02933
NCAM2 neural cell adhesion molecule 2 1.02933
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 1.02896
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.02896
MME membrane metallo-endopeptidase 1.02896
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.02858
TAT tyrosine aminotransferase 1.02858
TUBA1A tubulin, alpha 1a 1.02858
CBS cystathionine-beta-synthase 1.02708
ACAA2 acetyl-CoA acyltransferase 2 1.02671
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.02671
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.02634
PPAP2B phosphatidic acid phosphatase type 2B 1.02596
GPNMB glycoprotein (transmembrane) nmb 1.02559
BCL2L1 BCL2-like 1 1.02559
DUSP5 dual specificity phosphatase 5 1.02485
GAS6 growth arrest-specific 6 1.02485
TBPL1 TBP-like 1 1.02485
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 1.02485
PHC1 polyhomeotic homolog 1 (Drosophila) 1.0241
XPO5 exportin 5 1.0241
AMDHD2 amidohydrolase domain containing 2 1.02373
FASN fatty acid synthase 1.02336
DNAAF1 dynein, axonemal, assembly factor 1 1.02336
OLIG1 oligodendrocyte transcription factor 1 1.02336
ZBTB2 zinc finger and BTB domain containing 2 1.02299
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 1.02299
TUB tubby bipartite transcription factor 1.02299
HOOK3 hook microtubule-tethering protein 3 1.02262
IGBP1 immunoglobulin (CD79A) binding protein 1 1.02262
BRI3 brain protein I3 1.02262
MTA3 metastasis associated 1 family, member 3 1.02262
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.02262
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 1.02225
IL1R2 interleukin 1 receptor, type II 1.02188
HSPB1 heat shock 27kDa protein 1 1.02151
LDHB lactate dehydrogenase B 1.02077
SAT1 spermidine/spermine N1-acetyltransferase 1 1.01966
SESN2 sestrin 2 1.01928
MRPS2 mitochondrial ribosomal protein S2 1.0189
GSTP1 glutathione S-transferase pi 1 1.01852
CXCL10 chemokine (C-X-C motif) ligand 10 1.01814
GSTO1 glutathione S-transferase omega 1 1.01776
JAG1 jagged 1 1.01776
PHGDH phosphoglycerate dehydrogenase 1.01739
KLF10 Kruppel-like factor 10 1.01739
MCM3 minichromosome maintenance complex component 3 1.01701
FNDC1 fibronectin type III domain containing 1 1.01701
RAB6B RAB6B, member RAS oncogene family 1.01701
BCL7C B-cell CLL/lymphoma 7C 1.01663
BCAS1 breast carcinoma amplified sequence 1 1.01625
S100A16 S100 calcium binding protein A16 1.01625
PMP22 peripheral myelin protein 22 1.01587
GUSB glucuronidase, beta 1.01549
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.01512
MCM4 minichromosome maintenance complex component 4 1.01512
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.01324
ICAM1 intercellular adhesion molecule 1 1.01249
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.01249
DPP4 dipeptidyl-peptidase 4 1.01174
DCN decorin 1.01174
DESI2 desumoylating isopeptidase 2 1.01137
JAK1 Janus kinase 1 1.01137
MAPK9 mitogen-activated protein kinase 9 1.01099
ZFP37 ZFP37 zinc finger protein 1.01099
CHRDL1 chordin-like 1 1.01099
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 1.01062
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 1.01025
TSPAN1 tetraspanin 1 1.01025
CCBL2 cysteine conjugate-beta lyase 2 1.01025
SEC14L4 SEC14-like 4 (S. cerevisiae) 1.01025
KLHL29 kelch-like family member 29 1.01025
ATP11C ATPase, class VI, type 11C 1.01025